2021-08-01T00:00:00Z, Erçin, Esin, Dincel, Demet, DİNCEL, DEMET

2017-04-29, Babalı, Fatmanur, DİNCEL, DEMET, TOPÇU, GÜLAÇTI, DİNCEL, DEMET, TOPÇU, GÜLAÇTI

2013-12-01, Tekkeli, Şerife Evrim, Kızıltas, M. V., Dincel, Demet, TEKKELİ, ŞERİFE EVRİM, DİNCEL, DEMET

2019-03-17, DİNCEL, DEMET, UÇKAYA, FATİH, Özer, Ö.F., TOPÇU, GÜLAÇTI, DİNCEL, DEMET, UÇKAYA, FATİH, ÖZER, ÖMER FARUK, TOPÇU, GÜLAÇTI

2015-06-12, Aslan, Esin, DİNCEL, DEMET, Çakar, Begüm, TOPÇU, GÜLAÇTI, DİNCEL, DEMET, TOPÇU, GÜLAÇTI

2015-06-12, Ertaş, Abdülselam, Boğa, Mehmet, DİNCEL, DEMET, BÜTÜN, BURCU, Yeşil, Yeter, Soruhan, H.F., TOPÇU, GÜLAÇTI, KUŞMAN, TUBA, DİNCEL, DEMET, BÜTÜN, BURCU, TOPÇU, GÜLAÇTI

2023-01-08, Dincel D., DİNCEL, DEMET

2020-03-01T00:00:00Z, ASRAM SAĞIROĞLU, ALİ, Onal, Cem, DİNCEL, DEMET, Onal, Armagan, ASRAM SAĞIROĞLU, ALİ, TEKKELİ, ŞERİFE EVRİM, DİNCEL, DEMET

Polybrominated diphenyl ethers (PBDEs), which are used as flame retardants, are widely used additives so many different kind of materials that are consumed by public. Current researches reveal a significant increase in the levels of PBDEs in human biological fluids all around the world. According to International Agency for Research on Cancer (IARC), PBDEs are declarated as carcinogenic agents and additionally a considerable risks have been shown in animal studies such as liver damage, alteration of thyroid hormone levels, neurotoxicity and hazardous effects on development of fetus. Due to the simplicity of human exposure routes such as ingestion, inhalation or dermal contact, it gains high importance to quantify PBDEs in biological fluids. The exposure to PBDEs is critic aspecially during pregnancy, fetus development and infancy. Excretion of PBDEs in human milk is the focus area for researchers in recent years.

2011-12-01, Topcu, GÜLAÇTI, Ertas, Abdulselam, Ozturk, Mehmet, Dincel, Demet, Kilic, Turgut, Halfon, Belkis, TOPÇU, GÜLAÇTI, DİNCEL, DEMET

A new ent-kaurane diterpenoid, together with eight known ent-kauranes, were isolated from the petroleum ether and acetone extracts of the whole plant of Sideritis congesta P. H. Davis & Hub.-Mor. and their structures were elucidated as the new compound ent-7 alpha-acetoxy-16 beta, 18-dihydroxy-kaurane (7-acetyldistanol) (1) and the known compounds ent-3 beta,7 alpha-dihydroxy, 18-acetoxy-15 beta,16 beta-epoxykaurane (epoxyisolinearol) (2), sideroxol (3), sideridiol (4), siderol (5), 7-epicandicandiol (6), foliol (7), linearol (8) and sidol (9). Characterization of compounds 1-9 was based on spectral analyses and comparison with reported data, particularly the new compound 1 was identified by 1D- and 2D-NMR and mass spectroscopic analyses. The antioxidant potential of the extracts, and also of the ent-kauranes except for 7, was investigated by three methods including beta-carotene bleaching method, free radical scavenging activity and superoxide anion scavenging activity. The anticholinesterase activity was also evaluated for the ent-kauranes except for 7, and most of the diterpenes exhibited weak acetylcholinesterase inhibitory activity. However, almost all diterpenes exhibited some inhibitory activity against butyrylcholinesterase; particularly, compounds 3 and 6 exhibited better BChE inhibitory activity than the standard compound galanthamine. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.

2019-10-01T00:00:00Z, Dincel, Demet, Sağırlı, Ahmet Olcay, Topçu, Gülaçtı, DİNCEL, DEMET, TOPÇU, GÜLAÇTI