Person: KIRPINAR, İSMET
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İSMET
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KIRPINAR
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Publication Metadata only Akut dönemdeki kronik şizofreni hastasında yüksek doz n asetilsistein uygulaması Olgu sunumu(2014-11-16) ÖNÜR, NAFİYE SELCAN; BOYRAZ, RABİA KEVSER; KOÇER, EMEL; DEVECİ, ERDEM; KIRPINAR, İSMET; ÖNÜR, NAFIYE SELCAN; BOYRAZ, RABIA KEVSER; DEVECİ, ERDEM; KIRPINAR, İSMETPublication Metadata only Neurocognition in Patients with Acne Vulgaris(2014-11-01) DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMET; KOYUNCU, AHMET; ENGİN, İSMAİL; MELİKOĞLU, MEHMET; YILMAZ, ENVER DEMİREL; KOÇER, EMEL; DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Metadata only Is postpartum depression a specific diagnosis? A prospective study(2012-03-01T00:00:00Z) Kirpinar, Ismet; TEPELI, Isik Ozturk; GÖZÜM, SEBAHAT; Pasinlioglu, Turkan; KIRPINAR, İSMETObjective: The studies investigating the prevalence and incidence of postpartum depression (PPD), as well as its nosologic status have controversial results. This article is part of a prospective, epidemiological study concerning postpartum depression in Erzurum City, Eastern Turkey. The present study focuses on the prevalence and incidence of PPD at sixth weeks after delivery and its diagnostic distribution according to DSM-IV. Methods: Four hundred and seventy-nine pregnant women in their third trimester were arranged to be visited by trained community midwives at 7-10 days and sixth weeks after delivery. Data were collected by use of the questionnaires on detailed sociodemographic and health information at each visit and the participitants filled out the Edinburgh Postpartum Depression Scale (EPDS) at six weeks after delivery. Finally, mothers who had PPD diagnosis according to EPDS were visited by a psychiatrist in their homes where the SCID was administered to make a DSM-IV diagnosis and determine whether the depression occurred before or after delivery. Results: The prevalence rate of PPD measured by EPDS was 14% in this population. The incidence of PPD was estimated as 6% with clinical interviews. Most of the depressed mothers (74.0%) were diagnosed as major depressive disorder according to DSM-IV, but there were some other depressive states too. Conclusion: The prevalence and incidence rates of PPD do not appear to be significantly different from those of non-childbearing women. PPD should not be seen as a specific clinical entity as far as its diagnostic distribution is concerned. (Anatolian Journal of Psychiatry 2012;13:16-23)Publication Metadata only BRS:Neuroanatomy Nöroanatomi(2018-01-01) KIRPINAR, İSMET; KIRPINAR, İSMETPublication Metadata only Behavioral and molecular effects of perinatal music on rat pups(2016-11-16) Yanık, Hilal; CAN, BİRSEN; KIRPINAR, İSMET; BEKER, MERVE; ELİBOL, BİRSEN; KIRPINAR, İSMET; BEKER, MERVEPublication Open Access COVID-19 infection, vaccine status, and avoidance behaviors in adults with attention deficit and hyperactivity disorder: A cross-sectional study(2022-08-01) KILIÇ Ö.; BOYLU M. E.; Karakaya-Erdur S.; Suma-Berberoglu M.; Gudjonsson G.; Young S.; Deveci E.; KIRPINAR İ.; KILIÇ, ÖZGE; BOYLU, MUHAMMED EMİN; DEVECİ, ERDEM; KIRPINAR, İSMETObjective: We aim to examine infection risk and vaccine status of COVID-19 in attention deficit and hyperactivity disorder and evaluate the impact of demographic, clinical, and COVID-19-related factors on the infection status and behavioral avoidance of COVID-19. Methods: This cross-sectional study assessed adults with attention deficit and hyperactivity disorder recruited from an outpatient psychiatry clinic. Patients and healthy controls completed a survey on sociodemographic data, COVID-19 infection status, and vaccine status. COVID-19 Disease Perception Scale, COVID-19 Avoidance Attitudes Scale, Attitudes toward COVID-19 Vaccine Scale, Adult Attention Deficit and Hyperactivity Disorder Self-report Screening Scale for DSM-5, Adult Attention Deficit and Hyperactivity Disorder Self-Report Scale Symptoms Checklist, Patient Health Questionnaire-9, and State-Trait Anxiety Inventory were applied. Results: Ninety patients and 40 healthy controls participated. Patients did not differ from controls in COVID-19 infection and vaccine status, and behavioral avoidance of COVID-19. No demographic and clinical factor significantly affected the COVID-19 infection status. Patients scored higher than controls in the perception of COVID-19 as contagious (p = 0.038), cognitive avoidance of COVID-19 (p = 0.008), and positive attitudes toward the COVID-19 vaccine (p = 0.024). After adjustment of possible factors, a positive perception of the COVID-19 vaccine and a perception of COVID-19 as dangerous were the two factors significantly affecting behavioral avoidance of COVID-19 [R 2 = 0. 17, F(2) = 13.189, p < 0.0001]. Conclusion: Infection and vaccine status of COVID-19 in patients did not significantly differ from controls. No demographic and clinical factor significantly affected the COVID-19 infection status. Approximately four-fifths of the patients were fully vaccinated as recommended by national and global health organizations. This has increased the knowledge base showing that the COVID-19 vaccine is acceptable and receiving the vaccine is endorsed by ADHD patients. Attention deficit and hyperactivity disorder itself may provoke no kind of mental disturbance in sense of perception of the danger of this disease. Our findings have increased the knowledge base showing that the COVID-19 vaccine is acceptable and the actual practice of receiving the vaccine is endorsed in this population. Our message for practice would be to take into account not only the core symptoms and the comorbidities of the disorder but also the perception of the disease while exploring its link with COVID-19.Publication Metadata only ARE CHARACTER AND TEMPERAMENT TRAITS DETERMINANTS OF QUALITY OF LIFE IN HEALTY SUBJECTS?(2010-01-01T00:00:00Z) Yazici, E.; YAZICI, A. B.; AYDIN, Nurullah; Kirpinar, I.; KIRPINAR, İSMETPublication Unknown Reduced regulatory T cells with increased proinflammatory response in patients with schizophrenia(2020-06-01T00:00:00Z) Sahbaz, Cigdem; Zibandey, Noushin; KURTULMUŞ, AYŞE; Duran, Yazgul; Gokalp, Muazzez; KIRPINAR, İSMET; ŞAHİN, FİKRETTİN; Guloksuz, Sinan; AKKOÇ, TUNÇ; ŞAHBAZ, ÇIĞDEM DILEK; KURTULMUŞ, AYŞE; KIRPINAR, İSMETAim To investigate whether circulating T cells including regulatory T cells (Treg) and derived cytokines contribute to the immune imbalance observed in schizophrenia. Methods Forty patients with schizophrenia and 40 age, sex, body mass index, education, and smoking status-matched healthy controls (HC) are included in the study. We stained cells with anti-CD14, anti-CD3, anti-CD4, anti-CD8, anti-CD19, anti-CD20, and anti-CD16/56. Peripheral blood mononuclear cells (PBMCs) were isolated and stained with the human FoxP3 kit containing anti-CD4/anti-CD25 and intracellular anti-Foxp3. PBMCs were cultured for 72 h and stimulated with anti-CD3/anti-CD28. Cytokines (IL-2, IL-4, IL-6, IL-10, IFN-gamma, TNF-alpha, and IL-17A) were measured from the culture supernatant and plasma using the Th1/Th2/Th17 cytokine bead array kit. Results In comparison with HC, Treg percentages in schizophrenia were higher (1.17 +/- 0.63 vs 0.81 +/- 0.53, P = 0.005) in unstimulated but lower in the stimulated condition (0.73 +/- 0.69 vs 0.97 +/- 0.55, P = 0.011). Activated T cell percentages were higher in schizophrenia than HC in unstimulated (2.22 +/- 0.78 vs 1.64 +/- 0.89, P = 0.001) and stimulated (2.25 +/- 1.01 vs 1.72 +/- 1.00, P = 0.010) conditions. The culture supernatant levels of IL-6 (7505.17 +/- 5170.07 vs 1787.81 +/- 1363.32, P < 0.001), IL-17A (191.73 +/- 212.49 vs 46.43 +/- 23.99, P < 0.001), TNF-alpha (1557 +/- 1059.69 vs 426.57 +/- 174.62, P = 0.023), and IFN-gamma (3204.13 +/- 1397.06 vs 447.79 +/- 270.13, P < 0.001); and plasma levels of IL-6 (3.83 +/- 3.41vs 1.89 +/- 1.14, P = 0.003) and IL-17A (1.20 +/- 0.84 vs 0.83 +/- 0.53, P = 0.033) were higher in patients with schizophrenia than HC. Conclusion Our explorative study shows reduced level of Foxp3 expressing Treg in a stimulated condition with induced levels of proinflammatory cytokines in patients with schizophrenia.Publication Unknown Mirtazapinin Neden Olduğu Halüsinasyonlar Bir olgu sunumu(2015-11-29) KILIÇ, ALPEREN; ÖZTÜRK, AHMET; YILMAZ, ONUR; KIRPINAR, İSMET; ÖZTÜRK, AHMET; YILMAZ, ONUR; KIRPINAR, İSMETPublication Metadata only Problematic Patient(2021-06-01T00:00:00Z) KIRPINAR, İSMET; Ayhan, M. Suhan; GÜNEREN, Ethem; KIRPINAR, İSMET; GÜNEREN, ETHEMThe group of patients defined as -problematic patient- in aesthetic plastic surgical practice has distinctive features. The -problematic patient- is the patient who blocks the establishment of a therapeutic relationship with him/her. In other words, the patient who does not adapt to the patient role that the health-care professional expects, has different values, beliefs, or personal characteristics than he/she expects to see, and sometimes causes the professional to even suspect himself/herself. They are not good candidates for esthetic surgery, and they should definitely not be operated, so to speak, these patients should be removed from the game by removing a red card, and somehow be disqualified from the process.