Person: KIRPINAR, İSMET
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Publication Open Access Development of Hyperprolactinemia Induced by the Addition of Bupropion to Venlafaxine XR Treatment(2018-04-01) KILIÇ, Alperen; Ozturk, AHMET; Deveci, ERDEM; Kirpinar, Ismet; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMETHyperprolactinemia is characterized by abnormally increased serum prolactin levels. Menstrual irregularities and hyperprolactinemia can be caused by a variety of medical conditions as well as due to the use of some psychopharmacological drugs, namely antipsychotics; it can also develop during antidepressant treatment. Bupropion is an antidepressant functioning via the inhibition of noradrenaline and dopamine reuptake. The endocrine and sexual adverse events of this agent are rare. In the literature, only one case reporting hyperprolactinemia or galactorrhea caused by bupropion use is available. Here, we present the case of a patient diagnosed with depressive disorder and receiving venlafaxine, who developed hyperprolactinemia and oligomenorrhea after the addition of bupropion the ongoing treatment and showed serum prolactin levels decreased to normal ranges shortly after the discontinuation of bupropion.Publication Metadata only The psychiatric assessment schedule for adults with developmental disability checklist: reliability and validity of Turkish version(2017-01-01) GORMEZ, Aynur; Kirpinar, Ismet; KIRPINAR, İSMETAim/background: There is a lack of psychometric instruments to measure psychopathology in people with intellectual disabilities (ID). This may lead to underdiagnosis of treatable psychiatric comorbidities in this population. Psychiatric assessment schedule for adults with developmental disabilities (PAS-ADD) Checklist was developed as a screening tool designed for lay people. The PAS-ADD Checklist was created in English and was later on validated for other languages, including French and German. There is no psychometric measure available in Turkish to screen for or detect psychiatric symptoms in adults with ID. The aim of the present study was to present a psychometric evidence of the Turkish language version of the PAS-ADD Checklist. This is the first study aiming to present and validate a psychiatric screening instrument for adults with ID in Turkey.Publication Metadata only Psychiatric disorders in adults with mental retardation: prevalence and associated factors(2017-08-01) GÖRMEZ, AYNUR; Kirpinar, Ismet; KIRPINAR, İSMETObjective: Mental retardation (MR) is a spectrum of disorders characterized by deficits in intellectual and adaptive functioning which could result from several different etiological factors. Studies have shown that people with MR develop mental illness at rates similar to or higher than general population. We have not found any previous study carried out on adults with MR in Turkey. The aim of this study to determine the prevalence of mental disorders in Turkish population and to investigate associated factors. Methods: Participants aged 18 years and above and with a confirmed diagnosis of were recruited from care homes, rehabilitation centers and from people attending to outpatients for the first time for psychiatric assessment. A structured purpose designed Sociodemographic Form was used. Each participant underwent face to face assessment by a psychiatrist and their previous reports were also seen where available. Collateral history was provided by their families or caregivers who had known the person for at least 6 months. Diagnoses were established according to the DSM-5 criteria. Point prevalence of disorders were calculated and associated factors were investigated. Results: 63.5% of the participants met the criteria for one psychiatric disorder, whilst 21% received more than one diagnoses. The most common disorders were as follows: challenging behavior (34%), autism spectrum disorders (13.9%), anxiety-related disorders (13.9%) and attention deficit hyperactivity disorder (10.6%). Living in a care home and being young seemed to be associated with ill mental health. Conclusion: Our study demonstrates high psychiatric comorbidity in adults with MR. Young age and being in a care home seemed to be the only risk factors in our sample. These results highlight a need for increased awareness of mental health professionals and service providers about mental health of adults with MR for early diagnosis and interventions.Publication Metadata only Iron metabolism and haematological changes in anorexia nervosa: an adult case report(2018-06-01) GÖRMEZ, AYNUR; Kurtulmus, AYŞE; Kirpinar, Ismet; KURTULMUŞ, AYŞE; KIRPINAR, İSMETPublication Open Access Assessing and Managing Delirium in Surgical and Internal Medicine: an Overview(2016-12-01) Kirpinar, Ismet; KIRPINAR, İSMETDelirium is most common neuropsychiatric disorder that affects patients in surgical and internal medicine clinics. It is defined as a transient, usually reversible organic mental disorder that has a rapid onset and fluctuating course. Clinically, delirium is an acute or subacute organic mental syndrome that is characterized by a disturbance in attention (reduced ability to direct, focus, sustain, and shift attention), awareness (reduced orientation to the environment), and other cognitive abilities (e.g., memory deficit and disorientation) and is not better explained by preexisting, established, or other evolving neurocognitive disorders. Studies have found that between 10% and 20% of all adult inpatients are diagnosed with delirium and that it occurs in up to 50% of elderly inpatients. Delirium itself is not a disease but rather a clinical syndrome, which results from an underlying disease. There is evidence from the history, physical examination, or laboratory findings that the disturbance is a physiological consequence of an underlying medical condition, substance intoxication or withdrawal, use of a medication, or a toxin exposure, or it is a combination of these factors. Accurate identification of underlying causes and risk factors is essential in early stage diagnosis and treatment. Treatment of delirium requires the treatment of the underlying causes. Psychotropic medications are used to comfort patients or enable better patient management. This study aims to review the clinical characteristics, etiological and risk factors, and different methods to obtain an accurate diagnosis and treatment of delirium.