Person: KIRPINAR, İSMET
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Publication Open Access Clozapine Treatment and Thrombocytopenia: a Case Report(2014-09-01) Ozturk, AHMET; Deveci, ERDEM; DURSUN, Ali Emre; Soyucok, Etem; Kirpinar, Ismet; DEVECİ, ERDEM; KIRPINAR, İSMETPublication Open Access Development of Hyperprolactinemia Induced by the Addition of Bupropion to Venlafaxine XR Treatment(2018-04-01) KILIÇ, Alperen; Ozturk, AHMET; Deveci, ERDEM; Kirpinar, Ismet; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMETHyperprolactinemia is characterized by abnormally increased serum prolactin levels. Menstrual irregularities and hyperprolactinemia can be caused by a variety of medical conditions as well as due to the use of some psychopharmacological drugs, namely antipsychotics; it can also develop during antidepressant treatment. Bupropion is an antidepressant functioning via the inhibition of noradrenaline and dopamine reuptake. The endocrine and sexual adverse events of this agent are rare. In the literature, only one case reporting hyperprolactinemia or galactorrhea caused by bupropion use is available. Here, we present the case of a patient diagnosed with depressive disorder and receiving venlafaxine, who developed hyperprolactinemia and oligomenorrhea after the addition of bupropion the ongoing treatment and showed serum prolactin levels decreased to normal ranges shortly after the discontinuation of bupropion.Publication Metadata only The psychiatric assessment schedule for adults with developmental disability checklist: reliability and validity of Turkish version(2017-01-01) GORMEZ, Aynur; Kirpinar, Ismet; KIRPINAR, İSMETAim/background: There is a lack of psychometric instruments to measure psychopathology in people with intellectual disabilities (ID). This may lead to underdiagnosis of treatable psychiatric comorbidities in this population. Psychiatric assessment schedule for adults with developmental disabilities (PAS-ADD) Checklist was developed as a screening tool designed for lay people. The PAS-ADD Checklist was created in English and was later on validated for other languages, including French and German. There is no psychometric measure available in Turkish to screen for or detect psychiatric symptoms in adults with ID. The aim of the present study was to present a psychometric evidence of the Turkish language version of the PAS-ADD Checklist. This is the first study aiming to present and validate a psychiatric screening instrument for adults with ID in Turkey.Publication Metadata only The relationship between nine types temperament model with psychobiological personality model and affective temperament model(2015-04-01) YILMAZ, Enver Demirel; GENCER, Gorkem; UNAL, Ozge; OREK, Alp; Aydemir, Omer; Deveci, ERDEM; Kirpinar, Ismet; DEVECİ, ERDEM; KIRPINAR, İSMETObjective: This study aims to determine Nine Types Temperament Model (NTTM), which is a new temperament model, with Psychobiological Personality Model (PPM) and Affective Temperament Model (ATM) and define the possible relations between categories and dimensions and their degrees of predicting each other. Methods: The sample group consists of 206 healthy volunteers who did not receive any psychiatric treatment in their life and do not have any chronic disease. Structured Clinical Interview for DSM-IV (SCID-I), Structured Clinical Interview for DSM-III-R personality disorders (SCID-II), Temperament and Character Inventory (TCI), Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire Version (TEMPS-A) and Nine Type Temperament Scale (NTTS) were used to collect data. Results: Except for NTM3, NTM8 and NTM9 temperament categories, all NTTS categories have significant correlation with various TCI dimensions at a level r=0.40 and above. Except for NTM1, NTM5 and NTM9 temperament categories, all NTTS categories have significant correlation with various TEMPS-A categories at a level r=0.40 and above. According to the results of regression analyses, it is found that TCI dimensions and TEMPS-A categories can explain 29-63% of variance of NTTS temperament categories. Conclusion: This study indicates that although there are consistent and significant correlations between dimensions and categories of NTTS and the two scales widely used in psychiatry, there are conceptual differences between NTTM, PPM and ATM and temperament categories of NTTM have unique features.Publication Metadata only Reliability and Validity of the Turkish Version of the Health Anxiety Inventory(2013-01-01) Aydemir, Omer; Kirpinar, Ismet; Sati, Tulay; Uykur, Burak; Cengisiz, Cengiz; KIRPINAR, İSMETIntroduction: Health anxiety is seen in the clinical presentation of both somatoform disorders, especially hypochondriasis and anxiety disorders. In this study, we aimed to perform the reliability and validity analyses of the Turkish version of the Health Anxiety Inventory which is used in the assessment of health anxiety.Publication Metadata only Neuro cognitive functioning in young high-risk offspring having a parent with bipolar I disorder(2013-01-01) Deveci, ERDEM; Ozan, Erol; Kirpinar, Ismet; ORAL, Meltem; DALOGLU, Ali Gokhan; Aydin, Nazan; Ozturk, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMET; ÖZTÜRK, AHMETAim: To investigate attention, memory, verbal-linguistic ability, and executive functions in symptom-free young offspring having a parent with bipolar I disorder (BD1O) in comparison with healthy controls (CO).Publication Metadata only Role of Lymphocyte Subsets and T-Cell Profiles in the Immune Dysfunction of Schizophrenia(2018-05-01) SAHBAZ, Cigdem; Zibandeyeh, Noushin; Kurtulmus, AYŞE; AVAROGLU, Gamze; Kirpinar, Ismet; Sahin, Fikrettin; AKKOÇ, TUNÇ; ŞAHBAZ, ÇIĞDEM DILEK; KURTULMUŞ, AYŞE; KIRPINAR, İSMETPublication Metadata only Psychiatric disorders in adults with mental retardation: prevalence and associated factors(2017-08-01) GÖRMEZ, AYNUR; Kirpinar, Ismet; KIRPINAR, İSMETObjective: Mental retardation (MR) is a spectrum of disorders characterized by deficits in intellectual and adaptive functioning which could result from several different etiological factors. Studies have shown that people with MR develop mental illness at rates similar to or higher than general population. We have not found any previous study carried out on adults with MR in Turkey. The aim of this study to determine the prevalence of mental disorders in Turkish population and to investigate associated factors. Methods: Participants aged 18 years and above and with a confirmed diagnosis of were recruited from care homes, rehabilitation centers and from people attending to outpatients for the first time for psychiatric assessment. A structured purpose designed Sociodemographic Form was used. Each participant underwent face to face assessment by a psychiatrist and their previous reports were also seen where available. Collateral history was provided by their families or caregivers who had known the person for at least 6 months. Diagnoses were established according to the DSM-5 criteria. Point prevalence of disorders were calculated and associated factors were investigated. Results: 63.5% of the participants met the criteria for one psychiatric disorder, whilst 21% received more than one diagnoses. The most common disorders were as follows: challenging behavior (34%), autism spectrum disorders (13.9%), anxiety-related disorders (13.9%) and attention deficit hyperactivity disorder (10.6%). Living in a care home and being young seemed to be associated with ill mental health. Conclusion: Our study demonstrates high psychiatric comorbidity in adults with MR. Young age and being in a care home seemed to be the only risk factors in our sample. These results highlight a need for increased awareness of mental health professionals and service providers about mental health of adults with MR for early diagnosis and interventions.Publication Open Access Improvement in attention and executive functions during isotretinoin treatment in patients with acne(2013-06-01) Deveci, ERDEM; Ozturk, AHMET; Kirpinar, Ismet; ENGIN, Ragip Ismail; MELIKOGLU, Mehmet; SAKAT, Selcen Caferoglu; DEMIR, Muhammet; CANPOLAT, Serpil; DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMETBackground and Design: We assessed attention, memory, verbal-linguistic ability, and executive functions in acne vulgaris patients before and during isotretinoin treatment.Publication Metadata only Comparing ECT data of two different inpatient clinics: propofol or thiopental?(2013-10-01) YAZICI, Esra; BOSGELMEZ, Sukriye; Tas, Halil Ibrahim; KARABULUT, Umit; YAZICI, Ahmet Bulent; YILDIZ, MUSTAFA; Kirpinar, Ismet; KIRPINAR, İSMETObjective. This study compares the data of (modified) electroconvulsive theraphy (ECT) applications from two different inpatient clinics in Turkey: Kocaeli Derince Training and Research Hospital (Clinic-I) and Kocaeli University (Clinic-II). Methods. Recorded files of patients from the two clinics were compared in terms of ECT indications, number and duration of seizures, and anesthetic agents used (propofol vs. thiopental). ECT applications occurring between January 2011 and January 2013 were included in the study. Results. A total of 86 patients (9.5% of the inpatients) received ECT in Clinic-I and 103 patients (21.1% of the inpatients) in Clinic-II during the period studied. The yearly ECT rate (treated person rate per 10,000 per year) was 0.59/10,000 for Kocaeli (Turkey) as a whole. The overall number of ECT applications was 539 in Clinic-I and 999 in Clinic-II, and the average number of ECT sessions for each patient was 6.4 +/- 2.33 in Clinic-I and 9.69 +/- 4.66 in Clinic-II. The majority of indications were depressive disorders and insufficient response to medicine. Patients in the clinic which utilized thiopental as the anesthetic agent experienced more cardiovascular and respiratory side effects than the one which used propofol. The number of ECT sessions required was greater for patients with schizoaffective disorder than for others. Conclusions. The administration of ECT was considered to be a reliable method of treatment in these clinics. With respect to specific anesthetic agents, propofol was found to have less hemodynamic side effects and shorter seizure durations than thiopental.