Person: KIRPINAR, İSMET
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Publication Metadata only Anxiety and depression levels and personality traits of mastalgia patients(2014-01-01) Yılmaz, Enver Demirel; Deveci, ERDEM; Kadıoğlu, HÜSEYİN; Gençe, Ali Görkem; Ünal, Özge; Koçer, Emel; KIRPINAR, İSMET; DEVECİ, ERDEM; KADIOĞLU, HÜSEYİN; KIRPINAR, İSMETPublication Metadata only Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment(2019-01-01) ÖZTÜRK, AHMET; Şahan, Ebru; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMET; ÖZTÜRK, AHMET; ŞAHAN, EBRU; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMETObjective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.Publication Metadata only Somatoform Bozukluğu Olan Hastalarda Erken Dönem Uyumsuz Şemalar(2014-04-01) KIRPINAR, İSMET; DEVECİ, ERDEM; ZİHNİ, DEMET; KILIÇ, ALPEREN; KIRPINAR, İSMET; DEVECİ, ERDEMPublication Metadata only Neurocognition in Patients with Acne Vulgaris(2014-11-01) DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMET; KOYUNCU, AHMET; ENGİN, İSMAİL; MELİKOĞLU, MEHMET; YILMAZ, ENVER DEMİREL; KOÇER, EMEL; DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Metadata only Oxidative stress and inflammatory response in patients with psoriasis; is there any relationship with psychiatric comorbidity and cognitive functions?(2019-01-01) DEVECİ, ERDEM; Kocacenk, Tuba; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMET; DEVECİ, ERDEM; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Metadata only The relationship between nine types temperament model with psychobiological personality model and affective temperament model(2015-04-01) YILMAZ, Enver Demirel; GENCER, Gorkem; UNAL, Ozge; OREK, Alp; Aydemir, Omer; Deveci, ERDEM; Kirpinar, Ismet; DEVECİ, ERDEM; KIRPINAR, İSMETObjective: This study aims to determine Nine Types Temperament Model (NTTM), which is a new temperament model, with Psychobiological Personality Model (PPM) and Affective Temperament Model (ATM) and define the possible relations between categories and dimensions and their degrees of predicting each other. Methods: The sample group consists of 206 healthy volunteers who did not receive any psychiatric treatment in their life and do not have any chronic disease. Structured Clinical Interview for DSM-IV (SCID-I), Structured Clinical Interview for DSM-III-R personality disorders (SCID-II), Temperament and Character Inventory (TCI), Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire Version (TEMPS-A) and Nine Type Temperament Scale (NTTS) were used to collect data. Results: Except for NTM3, NTM8 and NTM9 temperament categories, all NTTS categories have significant correlation with various TCI dimensions at a level r=0.40 and above. Except for NTM1, NTM5 and NTM9 temperament categories, all NTTS categories have significant correlation with various TEMPS-A categories at a level r=0.40 and above. According to the results of regression analyses, it is found that TCI dimensions and TEMPS-A categories can explain 29-63% of variance of NTTS temperament categories. Conclusion: This study indicates that although there are consistent and significant correlations between dimensions and categories of NTTS and the two scales widely used in psychiatry, there are conceptual differences between NTTM, PPM and ATM and temperament categories of NTTM have unique features.Publication Metadata only Early Maladaptive Schemas in the Patients with Somatoform Disorders(2014-02-01) KIRPINAR, İSMET; Deveci, ERDEM; Zihni Çamur, Demet; Kılıç, Alperen; KIRPINAR, İSMET; DEVECİ, ERDEMPublication Metadata only Somatization disorder and hypochondriasis: As like as two peas? Somatizasyon bozukluğu ve hipokondriyazis: Bir elmanın iki yarısı mı?(2016-01-01) KIRPINAR, İSMET; DEVECİ, ERDEM; KILIÇ, Alperen; ZIHNI ÇAMUR, Demet; KIRPINAR, İSMET; DEVECİ, ERDEMObjective: Although the DSM-IV has provided some criteria for differential diagnosis of Hypochondriasis and Somatization Disorder, the differences between these disorders have rarely been studied. This study aimed to compare demographic and psychometric properties between hypochondriasis and somatization disorder. Methods: We investigated a sample of 100 patients aged 18-65 years who had been consecutively diagnosed as having hypochondriasis or somatization disorder via the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). The patients completed a battery of scales to measure anxiety, depression, dissociation, and somatosensorial amplification levels. Results: The only statistically significant difference between the two groups was in terms of health anxiety. The mean Health Anxiety Inventory (HAI) score was higher in the hypochondriasis group. No differences arose between the two groups in terms of other psychometric properties. Conclusions: Our results show that except for health anxiety levels, hypochondriasis and somatization disorder are similar in terms of psychological variables. The higher health anxiety levels in the hypochondriasis group support the opinions about the necessity of new categorization in these disorders.Publication Metadata only Is anxiety and depression related with personality in caregivers for patients with bipolar disorder?(2014-01-01T00:00:00Z) Yilmaz, Enver Demirel; DEVECİ, ERDEM; Güleç, Hüseyin; Gençer, Ali Görkem; Ünal, Özge; Koçer, Emel; KIRPINAR, İSMET; DEVECİ, ERDEM; KIRPINAR, İSMETPublication Metadata only The effects of focused ultrasound pulsation of nucleus accumbens in opioid-dependent rats(2019-01-01) Kılıç, Alperen; Yılmaz, Onur; Nabi, Aynur; Ergün, Arif Sanlı; Bozkurt, Ayhan; Kurtulmuş, Ayşe; Öztürk, AHMET; Aydın, Mehmet Şerif; Şahan, Ebru; DEVECİ, ERDEM; ÖZTÜRK, AHMET; EŞREFOĞLU, MUKADDES; KIRPINAR, İSMETBackground: Deep Brain Stimulation (DBS) is the only modality proven to be effective on selective stimulation of the deep brain structures. It was previously reported that, by using DBS, stimulation of nucleus accumbens (NA), a region that plays a pivotal role in the pathogenesis of substance addiction, is effective for the treatment of substance addiction. Objective: The purpose of the current study was to observe how the morphine-conditioned place preference changed in rats by stimulating NA with a non-invasive method, focused ultrasound (US) and to detect whether there would be any tissue damage caused by US waves. Methods: We used low-intensity focused ultrasound (LIFU), a noninvasive modality, in a place conditioning model to stimulate NA in rats. Results: At the initial stage of our study, we used morphine to induce place preference. As expected, morphine administration caused significant place preference. After the place preference was obtained by morphine, we divided the rats into two groups. One group received LIFU waves to NA and the other group received only sham, that is, no stimulation with US waves. Rats in both groups were continued to receive morphine. Then, we investigated whether LIFU and sham will reduce morphine-induced place preference or not. We observed that morphine-induced place preference had an ongoing raise in the sham group while no raise was detected in the ultrasound group. Although LIFU prevented the rats from the raise, it did not cause a significant reduction of morphine preference. Conclusion: We state that there is a need for future studies to investigate the effects of low-intensity focused ultrasound as an alternative treatment modality in addiction.