Person: KIRPINAR, İSMET
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Publication Metadata only Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment(2019-01-01) ÖZTÜRK, AHMET; Şahan, Ebru; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMET; ÖZTÜRK, AHMET; ŞAHAN, EBRU; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMETObjective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.Publication Metadata only Şiddetli Nörolojik Belirtilerle Giden Lityum İntoksikasyonunun Sağaltımı Bir Olgu Sunumu(2014-11-30) BAKAY, BETÜL; DEVECİ, ERDEM; ZİHNİ, DEMET; DURSUN, ALİ EMRE; ÖZTÜRK, AHMET; KIRPINAR, İSMET; DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Metadata only Neurocognition in Patients with Acne Vulgaris(2014-11-01) DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMET; KOYUNCU, AHMET; ENGİN, İSMAİL; MELİKOĞLU, MEHMET; YILMAZ, ENVER DEMİREL; KOÇER, EMEL; DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Metadata only Oxidative stress and inflammatory response in patients with psoriasis; is there any relationship with psychiatric comorbidity and cognitive functions?(2019-01-01) DEVECİ, ERDEM; Kocacenk, Tuba; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMET; DEVECİ, ERDEM; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Metadata only Mirtazapinin Neden Olduğu Halüsinasyonlar Bir olgu sunumu(2015-11-29) KILIÇ, ALPEREN; ÖZTÜRK, AHMET; YILMAZ, ONUR; KIRPINAR, İSMET; ÖZTÜRK, AHMET; YILMAZ, ONUR; KIRPINAR, İSMETPublication Metadata only Comparing remitted unipolar and bipolar depressive disorder according to the clinical features(2014-12-01) SOYUÇOK, ETEM; ÖZTÜRK, AHMET; AYDIN, NAZAN; KIRPINAR, İSMET; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Open Access Development of Hyperprolactinemia Induced by the Addition of Bupropion to Venlafaxine XR Treatment(2018-04-01) KILIÇ, Alperen; Ozturk, AHMET; Deveci, ERDEM; Kirpinar, Ismet; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMETHyperprolactinemia is characterized by abnormally increased serum prolactin levels. Menstrual irregularities and hyperprolactinemia can be caused by a variety of medical conditions as well as due to the use of some psychopharmacological drugs, namely antipsychotics; it can also develop during antidepressant treatment. Bupropion is an antidepressant functioning via the inhibition of noradrenaline and dopamine reuptake. The endocrine and sexual adverse events of this agent are rare. In the literature, only one case reporting hyperprolactinemia or galactorrhea caused by bupropion use is available. Here, we present the case of a patient diagnosed with depressive disorder and receiving venlafaxine, who developed hyperprolactinemia and oligomenorrhea after the addition of bupropion the ongoing treatment and showed serum prolactin levels decreased to normal ranges shortly after the discontinuation of bupropion.Publication Metadata only Depersonalization Associated with Kallman s Syndrome a Case Report(2015-04-19) ÖZTÜRK, AHMET; KILIÇ, ALPEREN; DURSUN, ALİ EMRE; DEVECİ, ERDEM; KIRPINAR, İSMET; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMETPublication Metadata only Bupropion induced Hyperprolactonamia: A case report. Bulletin of Clinical Psychopharmacology(2015-04-19) KIRPINAR, İSMET; Kılıç, Alperen; Öztürk, AHMET; KIRPINAR, İSMET; ÖZTÜRK, AHMETPublication Metadata only Bupropion induced hyperprolactinemia a case report(2015-04-19) KILIÇ, ALPEREN; ÖZTÜRK, AHMET; KIRPINAR, İSMET; ÖZTÜRK, AHMET; KIRPINAR, İSMET