Person:
KIRPINAR, İSMET

Profile Picture
Status
Organizational Units
OrgUnit Logo
Organizational Unit
Job Title
First Name
İSMET
Last Name
KIRPINAR
Name
Email Address
Birth Date

Filters

2013 - 20196
Reset filters

Settings

Author: ÖZTÜRK, AHMET × Type: Article × Item Type: Publication × Has files: false ×

Search Results

Now showing 1 - 6 of 6
  • No Thumbnail Available
    PublicationMetadata only
    Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment
    (2019-01-01) ÖZTÜRK, AHMET; Şahan, Ebru; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMET; ÖZTÜRK, AHMET; ŞAHAN, EBRU; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMET
    Objective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.
  • No Thumbnail Available
    PublicationMetadata only
    Neurocognition in Patients with Acne Vulgaris
    (2014-11-01) DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMET; KOYUNCU, AHMET; ENGİN, İSMAİL; MELİKOĞLU, MEHMET; YILMAZ, ENVER DEMİREL; KOÇER, EMEL; DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMET
  • No Thumbnail Available
    PublicationMetadata only
    Oxidative stress and inflammatory response in patients with psoriasis; is there any relationship with psychiatric comorbidity and cognitive functions?
    (2019-01-01) DEVECİ, ERDEM; Kocacenk, Tuba; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMET; DEVECİ, ERDEM; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMET
  • No Thumbnail Available
    PublicationMetadata only
    Neuro cognitive functioning in young high-risk offspring having a parent with bipolar I disorder
    (2013-01-01) Deveci, ERDEM; Ozan, Erol; Kirpinar, Ismet; ORAL, Meltem; DALOGLU, Ali Gokhan; Aydin, Nazan; Ozturk, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMET; ÖZTÜRK, AHMET
    Aim: To investigate attention, memory, verbal-linguistic ability, and executive functions in symptom-free young offspring having a parent with bipolar I disorder (BD1O) in comparison with healthy controls (CO).
  • No Thumbnail Available
    PublicationMetadata only
    The effects of focused ultrasound pulsation of nucleus accumbens in opioid-dependent rats
    (2019-01-01) Kılıç, Alperen; Yılmaz, Onur; Nabi, Aynur; Ergün, Arif Sanlı; Bozkurt, Ayhan; Kurtulmuş, Ayşe; Öztürk, AHMET; Aydın, Mehmet Şerif; Şahan, Ebru; DEVECİ, ERDEM; ÖZTÜRK, AHMET; EŞREFOĞLU, MUKADDES; KIRPINAR, İSMET
    Background: Deep Brain Stimulation (DBS) is the only modality proven to be effective on selective stimulation of the deep brain structures. It was previously reported that, by using DBS, stimulation of nucleus accumbens (NA), a region that plays a pivotal role in the pathogenesis of substance addiction, is effective for the treatment of substance addiction. Objective: The purpose of the current study was to observe how the morphine-conditioned place preference changed in rats by stimulating NA with a non-invasive method, focused ultrasound (US) and to detect whether there would be any tissue damage caused by US waves. Methods: We used low-intensity focused ultrasound (LIFU), a noninvasive modality, in a place conditioning model to stimulate NA in rats. Results: At the initial stage of our study, we used morphine to induce place preference. As expected, morphine administration caused significant place preference. After the place preference was obtained by morphine, we divided the rats into two groups. One group received LIFU waves to NA and the other group received only sham, that is, no stimulation with US waves. Rats in both groups were continued to receive morphine. Then, we investigated whether LIFU and sham will reduce morphine-induced place preference or not. We observed that morphine-induced place preference had an ongoing raise in the sham group while no raise was detected in the ultrasound group. Although LIFU prevented the rats from the raise, it did not cause a significant reduction of morphine preference. Conclusion: We state that there is a need for future studies to investigate the effects of low-intensity focused ultrasound as an alternative treatment modality in addiction.
  • No Thumbnail Available
    PublicationMetadata only
    Does psychotherapy improve alexithymia? A comparison study among patients with mild or moderate depression
    (2019-11-01) YILMAZ, ONUR; Mircik, Ali Barlas; Kunduz, Merve; Combas, Muge; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMET; YILMAZ, ONUR; MIRÇIK, ALİ BARLAS; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMET
    Background: Alexithymia is reported to be a risk factor for depression. Psychotherapy is efficient for treatment of depression. Yet, the effect of psychotherapies on alexithymia is poorly understood. Objectives: We aimed to compare Cognitive Behavioral Therapy (CBT), Existential Psychotherapy (ExP) and Supportive Counseling (SUP) for therapeutic efficacy and effect on alexithymia in depression. Methods: There were 22 patients for each patient group. Sessions were performed as eight consecutive weekly and following two monthly boosters. Sixty six healthy controls were added. Prior to the sessions, patients received Sociodemographic Data Form, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-1), Hamilton Depression Rating Scale (HDRS) and 20-item Toronto Alexithymia Scale (TAS-20). The control group received Sociodemographic Data Form, SCID-1 and TAS-20. Patients additionally received HDRS and TAS-20 after their weekly and booster sessions. Results: Patients- mean TAS-20 score was greater than of controls, however, it did not have a significant change throughout the study. Mean HDRS scores of ExP and CBT groups were lower than SUP group at the end. Discussion: Alexithymia did not improve with psychotherapy. The exception was effect of ExP on externally oriented thinking. Psychotherapies all improved depression. CBT and ExP were more helpful than SUP.