Person: KILIÇOĞLU DANE, PAKİZER BANU
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Publication Open Access Vitamin D status in the first-trimester: effects of Vitamin D deficiency on pregnancy outcomes(2016-01-01) Ates, SEDA; Sevket, OSMAN; ÖZCAN, PINAR; ÖZKAL, Fulya; Kaya, MEHMET ONUR; Dane, Banu; ATEŞ, SEDA; ŞEVKET, OSMAN; ÖZCAN, PINAR; KAYA, MEHMET ONUR; KILIÇOĞLU DANE, PAKİZER BANUObjective: To assess serum levels of 25-hydroxyvitamin D [25(OH)D] in the first trimester and to determine the factors affecting deficiency levels and its association with pregnancy outcomes. Methods: Serum 25(OH)D concentrations were measured at 11-14 weeks' gestation in 229 singleton pregnancies using liquid chromatography-tandem mass spectrometry. Results: The median serum 25(OH)D concentration was 10.8 ng/mL and 45.9% of women had severe vitamin D deficiency with concentrations of <10 ng/mL. Logistic regression analysis revealed that covered dressing style, lack of multivitamin intake, season of blood sampling (November-April) were factors associated with 25(OH)D deficiency. There was a negative correlation between 25(OH)D levels and gestational age at sampling. Low 25(OH)D levels were not associated with adverse pregnancy outcomes. Higher rate of cesarean section (CS) was noted in women with 25(OH)D ≥10 ng/mL compared to those with 25(OH)D < 10mg/ml (p= 0.01). Conclusion: A high prevalence of vitamin D deficiency was observed in early pregnancy which was related to dress code, use of multi-vitamins and season at sampling. Low 25(OH)D levels were not related with adverse pregnancy outcomes. Women with severe vitamin D deficiency were more likely to deliver vaginally.Publication Open Access Retrospective analysis of patients with placenta previa Plasenta previa olgularının retrospektif incelemesi(2015-12-01) BATMAZ, Gonca; MOLLA, Fulya; MOLLA, Taner; ÖZCAN, PINAR; Dansuk, RAMAZAN; Dane, Banu; ÖZCAN, PINAR; DANSUK, RAMAZAN; KILIÇOĞLU DANE, PAKİZER BANUAim: To evaluate risk factors of patients with placenta previa and investigate management strategies. Methods: A retrospective review of medical records of 41 cases with placenta previa who were followed up in our center. The cases were evaluated according to demographic features, presence of placental invasion of the uterus, and necessity of blood transfusion. Requirement for a peripartum hysterectomy, relaparotomy rates and neonatal outcomes were also addressed. All patients with placenta previa were considered for elective surgery. Results: Eighteen patients, who did not have any sign of uterine invasion in their antenatal sonographic evaluations, were observed alike during cesarean section. In 23 patients, uterine invasion was detected by antenatal sonographic evaluations, 15 patients underwent hysterectomy due to invasion. Subsequent laparotomy was needed in four patients in whom hysterectomy was performed. Out of 15 patients, who underwent hysterectomy, 9 had placenta accreata, 2 had placenta percreata, and 2 had placenta increata. Organ-preserving treatment was performed in 8 patients who had a suspicious uterine invasion owing to their antenatal sonographic evaluations. Conclusion: In our study, abnormal placental invasion was predicted by antenatal sonographic findings. Multidisciplinary approach is required for patients with placenta previa to determine appropriate mode and timing of delivery.Publication Open Access Effects of altitude changes on Doppler flow parameters for uterine, umbilical, and mid-cerebral arteries in term pregnancy: A pilot study(2015-12-01T00:00:00Z) Aksoy, Ayse Nur; Batmaz, Gonca; Dane, Banu; Kucur, Suna Kabil; Gozukara, Ilay; KILIÇOĞLU DANE, PAKİZER BANUObjective: We hypothesized that maternal and fetal circulations may be affected by moderately high altitudes. Therefore, we compared the differences in maternal and fetal Doppler flow parameters in women with term pregnancy living at a moderately high altitude (1890 m in Erzurum) with those of women living at the sea level (31 m in Istanbul).