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KILIÇOĞLU DANE, PAKİZER BANU

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PAKİZER BANU
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KILIÇOĞLU DANE
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  • PublicationOpen Access
    Pregnancy Outcome of Multiparous Women Aged over 40 Years.
    (2013-01-01) ATES, SEDA; BATMAZ, G; SEVKET, OSMAN; MOLLA, T; DANE, C; Dane, B; ATEŞ, SEDA; ŞEVKET, OSMAN; KILIÇOĞLU DANE, PAKİZER BANU
    women multiparaous in outcome obstetric and prenatal on age maternal of effect the evaluate to was study this of aim e.Objective ,group study (over and years 40 aged women including, conducted was study control case retrospective A. Methods and Materials age mean e. Results, 𝑛𝑛 𝑛 𝑛𝑛). group control (years 29–20 aged women and beyond or gestation s’week 20 at delivered who𝑛𝑛 𝑛 𝑛𝑛) associated was age maternal Advanced. group control the in years 3.2±4.25 versus years 7.1±2.41 was group study the in women of .(�𝑃𝑃𝑃� �� �𝑃�) 7
  • PublicationOpen Access
    Soluble TNF-Like Weak Inducer of Apoptosis as a New Marker in Preeclampsia: A Pilot Clinical Study.
    (2016-01-01) YILDIRIM, ZEYNEP BEYZA; SUMNU, A; BADEMLER, N; KILIC, ERDEM; SUMNU, G; KARADAG, S; GURSU, MELTEM; OZEL, A; BATMAZ, G; ATES, SEDA; Dane, B; OZTURK, S; YILDIRIM, ZEYNEP BEYZA; KILIÇ, ERDEM; GÜRSU, MELTEM; ATEŞ, SEDA; KILIÇOĞLU DANE, PAKİZER BANU
    ntroduction: All findings of preeclampsia appear as the clinical consequences of diffuse endothelial dysfunction. Soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) was recently introduced as a TNF related cytokine in various inflammatory and noninflammatory disorders. sTWEAK was found to be related to endothelial dysfunction in patients with chronic kidney disease. In our study we aimed to compare sTWEAK levels in women with preeclampsia to corresponding levels in a healthy pregnant control group. Materials and methods: The study was undertaken with 33 patients with preeclampsia and 33 normal pregnant women. The concentration of sTWEAK in serum was calculated with an enzyme linked immunosorbent assay (ELISA) kit. Results: Serum creatinine, uric acid, LDH levels, and uPCR were significantly higher in the patient group compared to the control group. sTWEAK levels were significantly lower in preeclamptic patients (332 ± 144 pg/mL) than in control subjects (412 ± 166 pg/mL) (p = 0.04). Discussion: Our study demonstrates that sTWEAK is decreased in patients with preeclampsia compared to healthy pregnant women. There is a need for further studies to identify the role of sTWEAK in the pathogenesis of preeclampsia and to determine whether it can be regarded as a predictor of the development of preeclampsia.
  • PublicationOpen Access
    Follicular variant of papillary thyroid carcinoma arising from a dermoid cyst: a rare malignancy in young women and review of the literature
    (2012-09-01) DANE, C; EKMEZ, M; KARACA, A; AK, A; Dane, B; KILIÇOĞLU DANE, PAKİZER BANU
    Objective Benign or mature cystic teratomas, also known as dermoid cysts, are composed of mature tissues, which can contain elements of all three germ cell layers. Malignant transformation of a mature cystic teratoma is more common in postmenopausal women, however, it can also, rarely, be identified in younger women. We present a case of a 19-year-old woman with malignant transformation of an ovarian mature cystic teratoma. Case Report Our case was a 19-year-old woman, who was diagnosed postoperatively with follicular variant of papillary thyroid carcinoma in a mature cystic teratoma. She underwent right cystectomy for adnexal mass. Postoperative metastatic workup revealed a non-metastatic disease and the patient did not undergo any further treatment. After 2 months, a near-total thyroidectomy was performed. Serum thyroglobulin levels were monitored on follow-up and the patient is asymptomatic. Conclusion Malignant transformation of a dermoid cyst is a rare ovarian neoplasm. We believe that unilateral oophorectomy or cystectomy is a reasonable treatment option for cases in which there is no evidence of capsular invasion, vascular invasion or gross metastasis, and preservation of fertility is desired. Total thyroidectomy was diagnosed in selected cases. Serial serum thyroglobulin should be used as a tumor marker for follow-up.