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Now showing 1 - 10 of 34
  • PublicationMetadata only
    Effectiveness of Titanium-Platelet-Rich Autograft: A Preliminary Report
    (2018-08-01) Nuhoglu, FADİME; Tugcu, Betul Cakmak; Tunali, MUSTAFA; Ozdemir, Hakan; NUHOĞLU, FADİME; TUĞCU, BETÜL; TUNALI, MUSTAFA
    Objective: The present study aimed to evaluate the effectiveness and reliability of titanium-platelet-rich fibrin (T-PRF) autograft implantation in patients who underwent this treatment method.
  • PublicationMetadata only
    Spectral domain optical coherence tomography for early detection of retinal alterations in patients using hydroxychloroquine
    (2013-04-01T00:00:00Z) ULVIYE, Yigit; Betul, Tugcu; NUR, Tarakcioglu; SELDA, Celik; TUĞCU, BETÜL
  • PublicationMetadata only
    Sensoryal şaşılıkta botulinum toksin ile kombine edilen horizontal kas cerrrahisinin sonuçları.
    (2015-11-05T00:00:00Z) Tuğcu, Betül; Öner, E; Özdemir, Mehmet Hakan; TUĞCU, BETÜL; ÖZDEMİR, MEHMET HAKAN
  • PublicationMetadata only
    Rehabilitation outcomes of children with cerebral palsy.
  • PublicationOpen Access
    Evaluation of amblyopic eyes with optical coherence tomography angiography and electrophysiological tests
    (2021-01-01T00:00:00Z) Hamurcu, Mualla; EKİNCİ, CANSU; Koca, Semra; TUĞCU, Betül; EKİNCİ, CANSU; TUĞCU, BETÜL
    Purpose: To investigate the structural and functional changes of the retina and optic nerve in amblyopia. Methods: Eighteen patients with unilateral anisometropic amblyopia and 27 age-matched healthy controls were involved in this study. All patients underwent optical coherence tomography angiography (OCTA), pattern visual evoked potential (pVEP), and flash electroretinogram (fERG). Results: There was no statistically significant difference in terms of the fovea] avascular zone (FAZ), perifoveal superficial density, whole superficial density, parafoveal deep density, perifoveal deep density among the eyes (P > 0 0.05). Significant differences were found only in superficial capillary plexus (SCP) vessel density in whole (P = 0.029) and parafoveal (P = 0.008) image. In electrophysiological tests, while VEP latencies of the amblyopic eyes increased compared to nonamblyopic eyes and controls (P = 0.027), VEP amplitudes decreased in amblyopic and nonamblyopic eyes compared to controls (P = 0.01), amplitudes of the rod (P = 0.027) and cones (P < 0.001) also decreased in amblyopic eyes compared to nonamblyopic and healthy eyes. When we assessed the correlation between the parameters of OCTA and electrophysiological test, only a significant correlation was found between parafoveal SCP vessel density and VEP amplitudes (r = 0.341). Conclusion: We found a significant decrease only in SCP vessel density of the OCTA parameters in amblyopic eyes compared to healthy eyes. We detected a significant relationship between parafoveal SCP vessel density and VEP parameters, which might be associated with the underlying pathophysiology of the amblyopia.
  • PublicationMetadata only
    Use of Botulinum Toxin A in the Treatment of Intermittent Exotropia: Factors Affecting Treatment Outcome
    (2022-01-01) Kunduracı M. S.; Kantarcı B.; Araz Erşan H. B.; Tuğcu B.; TUĞCU, BETÜL
    © 2022 Taylor & Francis.Purpose: To evaluate the efficiency of botulinum toxin A (BTA) injection in the treatment of intermittent exotropia (IXT) and determine factors affecting treatment outcome. Materials and methods: A total of 74 patients diagnosed with any type of IXT were included in the study. BTA injection was administered into both lateral rectus muscles. Gender, refractive error, age, pre- and post-injection measurements of ocular deviation, age at the time of the first BTA injection, number of injections, duration of misalignment, age at the onset of misalignment, presence of amblyopia, presence of anisometropia, preterm birth history, type of delivery, presence of any neurological disorder, follow-up period, postoperative ptosis, and vertical deviation were recorded. The final angle of deviation was used in the statistical analysis. Successful motor alignment was defined as a deviation of ≤10 prism diopters (PD) at distance. The relationship of all factors with treatment success was analyzed using the binary logistic regression analysis. Results: A total of 74 patients, 40 female and 34 male, were included in the study. All the patients were followed up for six to 53 months after the first BTA injection, and the mean follow-up was 16.1 ± 11.1 months. Before the first BTA injection of the patients, the mean amount of deviation was measured as 25.7 ± 14.2 (range, 0–60) PD at near and 37.1 ± 10.9 (range, 16–65) PD at distance. According to the most recent examination of the patients, the mean amount of deviation was 10.6 ± 9.8 (range, 0–45) PD at near and 16.4 ± 10.2 (range, 0–45) PD at distance. There was a statistically significant difference between the first and last examinations of the patients in relation to the amount of deviations measured at both near and distance (p < .001). Successful motor alignment (orthotropia within 10 PD for exodeviation) was achieved in 42 patients (56.7%). Thesuccess of treatment increased with the decreased amount of deviation at distance before the BTA injection. Conclusions: In patients with IXT, BTA injection into the lateral rectus muscles is an effective procedure, which is also less invasive and taking shorter time than surgery, and it can be considered as an alternative treatment option in those with small-medium angle IXT.
  • PublicationMetadata only
    Assessment of structural and functıonal vısual outcomes ın relapsıng remıttıng multıple sclerosıs wıth vısual evoked potentıals and optıcal coherence tomography.
    (2013-12-15T00:00:00Z) Tugcu, BETÜL; SOYSAL, A; KILIC, M; YUKSEL, B; KALE, N; YIGIT, U; ARPACI, B; TUĞCU, BETÜL
  • PublicationMetadata only
    Evaluation of retinal alterations in Parkinson disease and tremor diseases.
    (2019-11-02T00:00:00Z) TUĞCU, BETÜL; Arif, Melikov; Babacan, Yildiz Gulsen; Gokcal, Elif; Ercan, Rukiye; UYSAL, ÖMER; Ozdemir, Hakan; TUĞCU, BETÜL; BABACAN YILDIZ, GÜLSEN; GÖKÇAL, ELİF; ERCAN, RUKIYE; UYSAL, ÖMER; ÖZDEMİR, MEHMET HAKAN
    Optical coherence tomography (OCT) has been suggested as a method for detection of retinal alterations in neurodegenerative diseases. The usefulness of OCT as a diagnostic tool to differentiate Parkinson-s disease (PD) from other tremor diseases, remains unknown. We aimed to evaluate morphological changes of the retina in patients with PD, essential tremor (ET), essential tremor-Parkinson-s disease (ET-PD) using OCT. Forty-two eyes of 21 patients with PD, 24 eyes of 12 patients with ET, 24 eyes of 12 patients with ET-PD and 44 eyes of 22 age-matched healthy controls were included in the study. All participants underwent detailed neurological and ophthalmological examination. Measurements in all quadrants of macula and retinal nerve fiber layer (RNFL) thickness using OCT were recorded. There was no significant difference among the groups regarding age, sex. The average RNFL thickness was thinner in PD patients than that of ET (p = 0.032). The RNFL thickness in superior quadrant was lower in PD group compared with the ET and control group (p = 0.001, p = 0.016). Significant differences were observed in most of the macular thickness parameters excluding foveolar and foveal thickness (p = 0.865, 0.394). Correlations were found among several OCT parameters and disease duration or severity in all patient groups (p > 0.05). Retinal alterations were found in PD patients compared to ET. However, no significant retinal changes were detected by OCT in patients with ET and ET-PD compared to controls. According to our data, retinal assessments by OCT do not seem to be satisfactory for differentiation of these disorders.
  • PublicationMetadata only
    Anjioid çatlaklı bir Çocukta Bilateral Optik Disk Druseni ve Travmatik Koroid Rüptürü.
    (2016-03-01T00:00:00Z) Toklu, Enes; Özdemir, Mehmet Hakan; Tuğcu, Betül; Sezer, Taha; ÖZDEMİR, MEHMET HAKAN; TUĞCU, BETÜL
  • PublicationMetadata only
    Effects of levodopa on retina in Parkinson disease.