Person: TUĞCU, BETÜL
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Publication Sensoryal şaşılıkta botulinum toksin ile kombine edilen horizontal kas cerrrahisinin sonuçları.(2015-11-05T00:00:00Z) Tuğcu, Betül; Öner, E; Özdemir, Mehmet Hakan; TUĞCU, BETÜL; ÖZDEMİR, MEHMET HAKANPublication Spectral domain optical coherence tomography for early detection of retinal alterations in patients using hydroxychloroquine(2013-04-01T00:00:00Z) ULVIYE, Yigit; Betul, Tugcu; NUR, Tarakcioglu; SELDA, Celik; TUĞCU, BETÜLPublication Botulinum toxin A for the treatment of strabismus in children with neurological impairment.(2023-03-23T21:00:00Z) Tugcu, Betul; Araz-Ersan, Bilge; Özkan, Seyhan B; TUĞCU, BETÜLPurposes: To assess the efficacy of botulinum toxin A injection in the treatment of strabismus in patients with neurological impairment and evaluate the factors associated with treatment success. Methods: The study included 50 patients with strabismus and neurological impairment. In all children, botulinum toxin injection was performed into the appropriate extraocular muscle. The relationship between demographic features, clinical characteristics, and treatment success were analyzed. Results: In the study group, 34 patients had esotropia, and 16 patients had exotropia. As neurological problems, 36 patients had cerebral palsy, and 14 had hydrocephalus. The average follow-up period was 15.3 ± 7.3 months. The mean number of injections was 1.4 ± 0.6. The mean angle of deviation was 42.5 ± 13.2 PD before the treatment, which decreased to 12.8 ± 11.9 PD after the treatment. Successful motor alignment (orthotropia within 10 PD) was achieved in 60% of the patients. Binary logistic regression analysis revealed that esotropic misalignment and shorter duration of strabismus was significantly associated with treatment success in the study group. Patients with esotropia and lower angles of misalignment were more likely to be treated with a single injection. Conclusion: The use of botulinum toxin A for the treatment of strabismus in children with neurological impairment is a good alternative to conventional surgical therapy with a lower risk of overcorrection. The treatment outcome is better in esodeviations and shorter duration of strabismus, implying an advantage of early treatment.Publication Rehabilitation outcomes of children with cerebral palsy.(2014-02-01T00:00:00Z) YALCINKAYA, EY; CAGLAR, NS; Tugcu, BETÜL; TONBAKLAR, A; TUĞCU, BETÜLPublication Evaluation of amblyopic eyes with optical coherence tomography angiography and electrophysiological tests(2021-01-01T00:00:00Z) Hamurcu, Mualla; EKİNCİ, CANSU; Koca, Semra; TUĞCU, Betül; EKİNCİ, CANSU; TUĞCU, BETÜLPurpose: To investigate the structural and functional changes of the retina and optic nerve in amblyopia. Methods: Eighteen patients with unilateral anisometropic amblyopia and 27 age-matched healthy controls were involved in this study. All patients underwent optical coherence tomography angiography (OCTA), pattern visual evoked potential (pVEP), and flash electroretinogram (fERG). Results: There was no statistically significant difference in terms of the fovea] avascular zone (FAZ), perifoveal superficial density, whole superficial density, parafoveal deep density, perifoveal deep density among the eyes (P > 0 0.05). Significant differences were found only in superficial capillary plexus (SCP) vessel density in whole (P = 0.029) and parafoveal (P = 0.008) image. In electrophysiological tests, while VEP latencies of the amblyopic eyes increased compared to nonamblyopic eyes and controls (P = 0.027), VEP amplitudes decreased in amblyopic and nonamblyopic eyes compared to controls (P = 0.01), amplitudes of the rod (P = 0.027) and cones (P < 0.001) also decreased in amblyopic eyes compared to nonamblyopic and healthy eyes. When we assessed the correlation between the parameters of OCTA and electrophysiological test, only a significant correlation was found between parafoveal SCP vessel density and VEP amplitudes (r = 0.341). Conclusion: We found a significant decrease only in SCP vessel density of the OCTA parameters in amblyopic eyes compared to healthy eyes. We detected a significant relationship between parafoveal SCP vessel density and VEP parameters, which might be associated with the underlying pathophysiology of the amblyopia.Publication Effectiveness of Titanium-Platelet-Rich Autograft: A Preliminary Report(2018-08-01) Nuhoglu, FADİME; Tugcu, Betul Cakmak; Tunali, MUSTAFA; Ozdemir, Hakan; NUHOĞLU, FADİME; TUĞCU, BETÜL; TUNALI, MUSTAFAObjective: The present study aimed to evaluate the effectiveness and reliability of titanium-platelet-rich fibrin (T-PRF) autograft implantation in patients who underwent this treatment method.Publication Tear nitric oxide levels in Behçet-s disease.(2012-01-01T00:00:00Z) İŞCAN, Y; YIGIT, U; Tuğcu, BETÜL; ERDOĞAN, M; ERDOĞAN, DA; ÖNER, V; TAŞ, M; ÖZYAZGAN, Y; TUĞCU, BETÜLPublication Botulinum toxin A for the treatment of strabismus in children with neurological impairment Toxına botulínica tipo A para o tratamento de estrabısmo em crianças neurologicamente comprometidas(2023-01-01) TUĞCU B.; Araz-Ersan B.; Özkan S. B.; TUĞCU, BETÜLPurposes: To assess the efficacy of botulinum toxin A injection in the treatment of strabismus in patients with neurological impairment and evaluate the factors associated with treatment success. Methods: The study included 50 patients with strabismus and neurological impairment. In all children, botulinum toxin injection was performed into the appropriate extraocular muscle. The relationship between demographic features, clinical characteristics, and treatment success were analyzed. Results: In the study group, 34 patients had esotropia, and 16 patients had exotropia. As neurological problems, 36 patients had cerebral palsy, and 14 had hydrocephalus. The average follow-up period was 15.3 ± 7.3 months. The mean number of injections was 1.4 ± 0.6. The mean angle of deviation was 42.5 ± 13.2 PD before the treatment, which decreased to 12.8 ± 11.9 PD after the treatment. Successful motor alignment (orthotropia within 10 PD) was achieved in 60% of the patients. Binary logistic regression analysis revealed that esotropic misalignment and shorter duration of strabismus was significantly associated with treatment success in the study group. Patients with esotropia and lower angles of misalignment were more likely to be treated with a single injection. Conclusion: The use of botulinum toxin A for the treatment of strabismus in children with neurological impairment is a good alternative to conventional surgical therapy with a lower risk of over-correction. The treatment outcome is better in esodeviations and shorter duration of strabismus, implying an advantage of early treatment.Publication Adie-Holmes syndrome associated with COVID-19 infection: A case report(2021-03-01T00:00:00Z) Tutar, Nurhan Kaya; Kale, Nilufer; TUĞCU, Betül; TUĞCU, BETÜLWith increasing experience, it has been suggested that the SARS-CoV-2 virus has a neurotropic effect. Here, we present a case of a tonic pupil who developed after COVID-19 infection. A 36-year-old woman presented with progressive photophobia and blurred vision. On neurological examination, loss of deep tendon reflexes accompanying a tonic pupil was detected and brain MR imaging was normal. With this case, we aimed to describe a rare pattern of neurological involvement caused by the possible SARS-CoV-2 virus.Publication Botulinum toxin as an adjunct to monocular recession-resection surgery for large-angle sensory strabismus.(2017-04-01) Tuğcu, BETÜL; SÖNMEZAY, E; Nuhoğlu, FADİME; ÖZDEMIR, HÜSEYİN; ÖZKAN, SB; TUĞCU, BETÜL; NUHOĞLU, FADİME; ÖZDEMİR, MEHMET HAKAN