Person: TORUN, EMEL
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TORUN
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EMEL
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- PublicationOpen AccessThe role of vitamin D receptor gene polymorphisms in Turkish infants with urolithiasis.(2016-01-01T00:00:00Z) Goknar, N; Öktem, F; Torun, EMEL; Gok, O; Demir, AD; Kucukkoc, M; Kilic, U; TORUN, EMEL
- PublicationMetadata onlyÇocuk polikliniklerinde izlenen vulvovalinit olgularının değerlendirilmesi(2019-03-31) BURSAL DURAMAZ B.; USTABAŞ KAHRAMAN F.; TORUN E.; VEHAPOĞLU TÜRKMEN A.; TÜREL Ö.; USTABAŞ KAHRAMAN, FEYZA; TORUN, EMEL; VEHAPOĞLU TÜRKMEN, AYSEL; TÜREL, ÖZDEN
- PublicationMetadata onlyChildhood pulmonary tuberculosis and contribution of bronchoscopy to diagnosis: Analysis of 204 cases(2011-06-11T00:00:00Z) Çakır, Erkan; Kut, Arif; Çakır, Fatma Betül; Torun, Emel; ÇAKIR, ERKAN; ÇAKIR, FATMA BETÜL; TORUN, EMEL
- PublicationMetadata onlyBrown Sendromu: Olgu sunusu(2014-04-11) TORUN E.; ORUÇLU Ş.; USTABAŞ KAHRAMAN F.; ARUÇİ N.; AKKAN J. C.; TORUN, EMEL; USTABAŞ KAHRAMAN, FEYZA
- PublicationOpen AccessRenal tubular function and urinary N-acetyl-beta-d-glucosaminidase and kidney injury molecule-1 levels in asthmatic children(2016-12-01) DEMIR, Aysegul Dogan; GOKNAR, Nilufer; OKTEM, Faruk; Ozkaya, EMİN; Yazici, MEBRURE; Torun, EMEL; Vehapoglu, Aysel; KUCUKKOC, Mehmet; ÖZKAYA, EMİN; YAZICI, MEBRURE; TORUN, EMEL; VEHAPOĞLU TÜRKMEN, AYSELBackground: Asthma is a chronic inflammatory disorder of the airways which results in chronic hypoxia. Chronic hypoxia and inflammation can affect renal tubular function. Objectives: The aim of this study was to investigate renal tubular function and early kidney injury molecules such as urinary N-acetyl-betaglucosaminidase (NAG) and kidney injury molecule-1 (KIM-1) excretion in children with asthma. Methods: Enrolled in the study were 73 children diagnosed with asthma and 65 healthy age- and gender-matched control subjects. Urine pH, sodium, phosphorus, potassium, microalbumin, creatinine, NAG, KIM-1, and serum creatinine, sodium, phosphorus were evaluated. The diagnosis of asthma and classification of mild or moderate were done according to the Global Initiative for Asthma guidelines. Results: Serum sodium, phosphorus, creatinine, and urinary microalbumin were within normal levels in the both groups. Urinary pH, sodium, potassium, phosphorus, microalbumin, and KIM-1 excretions were similar between the control and study groups. Tubular phosphorus reabsorption was within normal limits in two groups. Urine NAG was elevated in the study group (P = 0.001). Urinary KIM-1 and NAG levels were positively correlated (r = 0.837; P = 0.001). When children with mild and moderate asthma were compared, all of the parameters were similar (P >0.05). Conclusions: This study showed that chronic asthma can lead to subtle renal impacts. We suggest that in children with asthma, urinary NAG level is a more valuable parameter to show degree of renal tubular injury than markers such as microalbumin and KIM-1. Chronic hypoxy and inflammation probably contributes to these subclinical renal effects.
- PublicationMetadata onlyTotal oxidative stress, total antioxidant status and paraoxonase activity in pediatric patients with bronchiolitis obliterans(2014-09-07T00:00:00Z) Gedik, Ahmet Hakan; Çakır, Erkan; Gökdemir, Yasemin; Uyan, Seda; Koçyiğit, Abdürrahim; Torun, Emel; Karadağ, Bülent Taner; Ersu, Refika; Karakoç, Fazilet; ÇAKIR, ERKAN; KOÇYİĞİT, ABDÜRRAHİM; TORUN, EMEL
- PublicationMetadata onlyManganese superoxide dismutase Ala16Val gene polymorphism in obese children with metabolic syndrome(2013-09-22) ÖZGEN, İLKER TOLGA; TORUN, EMEL; ERGEN, ARZU; KARAGEDIK, HANDE; CESUR, YAŞAR; AKSU, MEHMET ŞIRIN; ÖKTEM, FATMA BETÜL; ZEYBEK, UMIT; ÖZGEN, İLKER TOLGA; TORUN, EMEL; CESUR, YAŞAR; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIR, FATMA BETÜL
- PublicationOpen AccessA case of severe combined immunodeficiency caused by adenosine deaminase deficiency with a new mutation.(2018-02-01) Turel, O; AYGUN, D; KARDAS, M; TORUN, EMEL; HERSHFIELD, M; CAMCıOGLU, Y; TÜREL, ÖZDEN; TORUN, EMELAdenosine deaminase (ADA) deficiency is among the most common causes of severe combined immunodeficiency, characterized by dysfunction of the T, B, and natural killer (NK) cells (T-B-NK-SCID) and severe lymphopenia.1 ADA is a key enzyme in the purine salvage pathway, the absence of which causes lymph-toxic deoxyadenosine triphospate (dATP) accumulation, inhibiting ribonucleotide reductase, a critical enzyme for DNA replication and repair. This effect impairs the lymphocyte development and function resulting in severe combined immune deficiency (SCID).1,2 ADA deficiency is autosomal recessively inherited through mutations in the ADA gene, which is located on chromosome 20q13.12. Herein, we will describe the identification of a novel splicing mutation in the ADA gene in a patient with SCID
- PublicationMetadata onlyAssociation of Myeloperoxidase Gene Polymorphism With Iron Deficiency Anemia in Turkish Children(2021-10-01T00:00:00Z) USTABAŞ KAHRAMAN, Feyza; ÇAKIR, FATMA BETÜL; BUHUR PİRİMOĞLU, MELTEM; TORUN, EMEL; Ergen, Hayriye Arzu; DOĞAN DEMİR, AYŞEGÜL; USTABAŞ KAHRAMAN, FEYZA; ÇAKIR, FATMA BETÜL; TORUN, EMEL; DOĞAN DEMİR, AYŞEGÜLThis study was performed to investigate the gene polymorphisms of the myeloperoxidase (MPO) enzyme and to determine whether MPO gene polymorphisms influence the response to iron therapy in pediatric patients with iron deficiency anemia (IDA). In this case-control study, 50 Turkish children with IDA and 50 healthy controls were enrolled. Three MPO gene alleles were selected for genotyping in the study: GG, AG, and AA. The relationships of alleles with IDA were analyzed and compared in patients and controls. Pretreatment and posttreatment laboratory parameters and gene polymorphisms were compared in the patient group. There was a significant difference between patients with IDA and controls regarding genotype frequencies of the AA, GG, and AG alleles (P=0.005). However, the AG allele was found to be associated with variations in hemoglobin, red blood cell, hematocrit, mean corpuscular volumes, and mean corpuscular Hb concentrations levels. The frequency of AA, GG, and AG alleles of the MPO gene was potentially associated with changes in iron metabolism and the AG allele led to variations in various hemogram parameters.
- PublicationMetadata onlySkin temperature measurement using an infrared thermometer on patients who have been exposed to cold.(2013-12-01) ERENBERK, UFUK; TORUN, EMEL; OZKAYA, EMİN; Uzuner, SELÇUK; DEMIR, AD; DUNDAROZ, R; ERENBERK, UFUK; TORUN, EMEL; ÖZKAYA, EMİN; UZUNER, SELÇUK