Person: SOYSAL, PINAR
12 results
Search Results
Now showing 1 - 10 of 12
Publication Open Access Triple Test Plus Rapid Cognitive Screening Test: A Combination of Clinical Signs and A Tool for Cognitive Assessment in Older Adults.(2019-08-15) Isik, AT; Koc, Okudur; Dokuzlar, O; Kaya, D; SOYSAL, PINARLess time-consuming, easy-to-apply and more reliable cognitive screening tests are essential for use in primary care. The aim of this study was to investigate the diagnostic value of the Turkish version of the Rapid Cognitive Screen (RCS-T) and Triple Test individually and the combination of RCS-T with each sign and Triple Test to screen elderly patients for cognitive impairment (CI). A total of 357 outpatients aged 60 or older, who underwent comprehensive geriatric assessment, were included in the study. Presence or absence of attended alone sign (AAS), head-turning sign, and applause sign was investigated. The mean age of the patients was 74.29 ± 7.46. Of those, 61 patients (28 men, 33 women) had Alzheimer's disease (AD), 59 patients had mild cognitive impairment (MCI) (29 men, 30 women), and 237 (80 men, 157 women) were cognitively robust. The sensitivity of the combination of RCS-T and negative for AAS for CI, AD and MCI is 0.79, 0.86 and 0.61, respectively; the specificity was 0.92, 0.93 and 0.92, respectively; and the positive and negative predictive values revealed good diagnostic accuracy. The combination of RCS-T and negative for AAS is a simple, effective and rapid way to identify possible CI in older adults.Publication Open Access What is the relationship between frailty and orthostatic hypotension in older adults?(2019-03-01) KOCYIGIT, SE; ISIK, AT; DOKUZLAR, O; AYDIN, AE; BULUT, EA; Soysal, PINAR; SOYSAL, PINARBackground Frailty and orthostatic hypotension (OH), which is common in older adults, is associated with morbidity and mortality. The relationship between them remains unclear. The aim of the study is to determine whether there is a relationship between frailty and OH. Methods A total of 496 patients who were admitted to the geriatric clinic and underwent comprehensive geriatric assessment were retrospectively reviewed. In a cross-sectional and observational study, OH was measured by the Head-up Tilt Table test at 1, 3, and 5 min (respectively, OH1, OH3, and OH5) and the frailty was measured by the Fried’s frailty scale. Results The mean age of all patients was 75.4 ± 7.38. The prevalence of females was 69.8%. When the frail people were compared with the pre-frail and the robust ones, the frailty was associated with OH1. There was no relationship between the groups in terms of OH1 when the pre-frail group was compared with the robust group. OH3 were higher in the frail group than in the pre-frail group (P < 0.05) and the OH5 were higher in the frail group than in the pre-frail and robust group (P < 0.05), but OH3 and OH5 were not associated with frailty status when they were adjusted for age (P > 0.05). Slowness and weakness were associated with OH1 (P < 0.05), whereas the other components of the Fried’s test were not. Conclusions Frailty may be a risk factor for OH1. The 1st min measurements of OH should be routinely evaluated in frail older adults to prevent OH-related poor outcomes.Publication Open Access Health behaviours and mental and physical health status in older adults with a history of homelessness: a cross-sectional population-based study in England.(2019-06-14) López-Sánchez, GF; Jackson, SE; Veronese, N; Moller, E; Johnstone, J; Firth, J; Grabovac, I; Yang, L; SOYSAL, PINARObjectives: This study compared (1) levels of engagement in lifestyle risk behaviours and (2) mental and physical health status in individuals who have previously been homeless to those of individuals who have not. Design: Cross-sectional. Participants: Data were from participants (n=6931) of the English Longitudinal Study of Ageing. : Measures : Participants reported whether they had ever been homeless. We used regression models to analyse associations between homelessness and (1) cigarette smoking, daily alcohol consumption and physical inactivity, adjusting for sociodemographic covariates (age, sex, ethnicity, highest level of education, marital status and household non-pension wealth) and (2) self-rated health, limiting long-standing illness, depressive symptoms, life satisfaction, quality of life and loneliness, adjusting for sociodemographics and health behaviours. Results: 104 participants (1.5%) reported having been homeless. Individuals who had been homeless were significantly more likely to be physically inactive (OR 1.62, 95% CI 1.44 to 2.52), report fair/bad/very bad self-rated health (OR 1.75, 95% CI 1.07 to 2.86), have a limiting long-standing illness (OR 2.66, 95% CI 1.65 to 4.30) and be depressed (OR 3.06, 95% CI 1.85 to 5.05) and scored lower on measures of life satisfaction (17.34 vs 19.96, p<0.001) and quality of life (39.02 vs 41.21, p=0.013). Rates of smoking (20.2% vs 15.4%, p=0.436), daily drinking (27.6% vs 22.8%, p=0.385) and loneliness (27.1% vs 21.0%, p=0.080) were also elevated. Conclusions: Those who were once homeless have poorer mental and physical health outcomes and are more likely to be physically inactive. Interventions to improve their health and quality of life are required.Publication Open Access The relationship between polypharmacy and trajectories of cognitive decline in people with dementia: A large representative cohort study.(2019-06-01) Perera, G; Onder, G; Petrovic, M; Cherubini, A; Maggi, S; Soysal, PINAR; Shetty, H; Molokhia, M; Isik, AT; Smith, L; Stubbs, B; Stewart, R; Veronese, N; Mueller, C; SOYSAL, PINARPublication Open Access Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies.(2019-08-11) Grabovac, I; Soysal, PINAR; Veronese, N; Stefanac, S; Haider, S; Koyanagi, A; Meilinger, M; ABBS, AD; Stubbs, B; McDermott, DT; Firth, J; Di, Gennaro; Demurtas, J; Jackson, SE; Yang, L; Smith, L; SOYSAL, PINARPublication Open Access Mini Nutritional Assessment Scale-Short Form can be useful for frailty screening in older adults(2019-01-01T00:00:00Z) SOYSAL, PINAR; Veronese, Nicola; Arik, Ferhat; Kalan, Ugur; Smith, Lee; IŞIK, AHMET TURAN; SOYSAL, PINARAim: Mini Nutritional Assessment-Short Form MNA-SF) is used to assess nutritional status in older adults, but it is not known whether it can be used to define frailty. This study was aimed to investigate whether or not MNA-SF can identify frailty status as defined by Fried-s criteria.Publication Open Access Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis.(2019-11-01) Soysal, PINAR; Pizzol, D; Demurtas, J; Stubbs, B; Mason, C; Isik, AT; Smith, L; Veronese, N; SOYSAL, PINARGlobally, there is increasing usage and legalization of cannabis. In addition to its reported therapeutic effects, cannabis has several health risks which are not clearly defined. Erectile dysfunction (ED) is the most common male sexual disorder and there are plausible mechanisms linking cannabis use to ED. No attempt has been made to collate the literature on this topic. The aim of this review was to summarize the prevalence and risk of ED in cannabis users compared to controls. A systematic review of major databases from inception to January 1, 2019, without language restriction, was undertaken to identify studies investigating cannabis use and presence of ED. The analysis compared the prevalence of ED in cannabis users versus controls. Consequently, the odds ratio (OR) with 95% confidence intervals (CI) was calculated, applying a random-effect model. Five case–control studies were included with data from 3,395 healthy men, 1,035 using cannabis (smoking) and 2,360 nonusers. The overall prevalence of ED in cannabis users was 69.1% (95% CI: 38.0–89.1), whilst the correspondent figure in controls was 34.7% (95% CI: 20.3–52.7). The OR of ED in cannabis users was almost four times that of controls (OR = 3.83; 95% CI: 1.30–11.28; p = .02), even if characterized by high heterogeneity (I2 = 90%) and the prediction intervals overlapped 1.00 (95% CI: 0.35–7.26). Data suggest that ED is twice as high in cannabis users compared to controls. Future longitudinal research is needed to confirm/refute this and explore if a dose–response relationship between cannabis and ED may be evident.Publication Open Access Sexual Activity is Associated with Greater Enjoyment of Life in Older Adults.(2019-03-01) SMITH, L; Soysal, PINAR; JACKSON, SE; STUBBS, B; VERONESE, N; YANG, L; SOYSAL, PINARBackground: Relationships among sexual activity, problems and concerns, and well-being among older adults have not been fully explored. Aim: To investigate associations among sexual activity, problems and concerns, and experienced well-being in a representative sample of older adults. Methods: In this cross-sectional analysis from the English Longitudinal Study of Ageing, sexual behavior, problems, and concerns were assessed via a self-completed questionnaire. Covariates included age, partnership status, socioeconomic status, smoking status, alcohol intake, limiting long-standing illness, and depressive symptoms. Data were analyzed using 1-way independent analysis of variance. Main Outcome Measure: Enjoyment of life was assessed with the pleasure subscale of the CASP-19 (Control, Autonomy, Self-realization, and Pleasure), a validated measure of quality of life specific to older age. Results: Data on sexual activity and enjoyment of life were available for a total of 3,045 men and 3,834 women (mean age 64.4 years in men and 65.3 years in women). Men and women who reported any sexual activity in the past year had significantly higher mean enjoyment of life scores compared with those who were not sexually active (men, 9.75 vs 9.44 [P < .001]; women, 9.86 vs 9.67 [P ¼ .003]). Among sexually active men, frequent ( 2 times a month) sexual intercourse (P < .001) and frequent kissing, petting, or fondling (P < .001) were associated with greater enjoyment of life. Among sexually active women, frequent kissing, petting, or fondling was also associated with greater enjoyment of life (P < .001), but there was no significant association with frequent intercourse (P ¼ .101). Concerns about one’s sex life and problems with sexual function were strongly associated with lower levels of enjoyment of life in men and to a lesser extent in women. Conclusion: This is among the first studies to show that well-being is higher among older adults when they are sexually active. Preferences regarding the expression of sexual activity differed between the sexes. Further longitudinal research is needed to confirm a causal association between sexual activity and well-being.Publication Open Access Associations between sexual activity and weight status: Findings from the English Longitudinal Study of Ageing(2019-09-01T00:00:00Z) Smith, Lee; Yang, Lin; Forwood, Suzanna; Lopez-Sanchez, Guillermo; Koyanagi, Ai; Veronese, Nicola; SOYSAL, PINAR; Grabovac, Igor; Jackson, Sarah; SOYSAL, PINARObjectivePublication Open Access Frequency and coincidence of geriatric syndromes according to age groups: single-center experience in Turkey between 2013 and 2017.(2018-10-04T00:00:00Z) Ates, Bulut; Soysal, Pınar; Isık, At; SOYSAL, PINAR