Person: SOYSAL, PINAR
20 results
Search Results
Now showing 1 - 10 of 20
Publication Metadata only Ethnic Differences in Magnesium Intake in US Older Adults: Findings from NHANES 2005-2016(2018-12-01) Jackson S. E.; Smith L.; Grabovac I.; Haider S.; Demurtas J.; Lopez-Sanchez G. F.; SOYSAL P.; Redsell S.; IŞIK A. T.; Yang L.; SOYSAL, PINARMagnesium plays a crucial role in hundreds of bodily processes relevant to aging, but consumption of dietary magnesium intake has been shown to be inadequate in a large proportion of older adults. Identifying groups at risk of low magnesium intake is important for informing targeted advice. Using data from the National Health and Nutrition Examination Survey (NHANES) 2005-2016, we examined the association between ethnicity (Caucasian/African American/Hispanic/other) and magnesium intake in a large representative sample of U.S. older adults (65 y, n = 5682, mean (SD) 72.9 (0.10) y). Analyses adjusted for total energy intake and a range of relevant covariates. Overall, 83.3% of participants were not meeting the recommended level of dietary magnesium intake, ranging from 78.1% of other ethnic groups to 90.6% of African Americans. In the fully adjusted model, magnesium intake was lower among African American older adults (-13.0 mg/d, 95% CI: -18.8 to -7.2), and higher among Hispanics (14.0 mg/d, 95% CI: 7.5 to 20.5) and those from other ethnic groups (17.2, 95% CI: 3.8 to 30.5) compared with Caucasian older adults. These results highlight the need for targeted interventions to increase magnesium intake in U.S. older adults, with a focus on African Americans, in order to reduce the burden of morbidity and ethnic inequalities in health in later life.Publication Metadata only Which Cholinesterase Inhibitor is the Safest for the Heart in Elderly Patients With Alzheimer-s Disease?(2012-05-01T00:00:00Z) ISIK, Ahmet Turan; BOZOGLU, Ergun; YAY, Adnan; Soysal, PINAR; ATESKAN, Umit; SOYSAL, PINARObjective: Cholinesterase inhibitors (ChEIs) are widely used for the treatment of Alzheimer-s disease (AD); however, their cholinergic side effects on the cardiovascular system are still unclear. In this study, we aimed to examine the side effects caused by donepezil, rivastigmine, and galantamine on cardiac rhythm and postural blood pressure changes in elderly patients with AD. Methods: Of 204 consecutive elderly patients who were newly diagnosed with AD, 162 were enrolled and underwent comprehensive geriatric assessments. The electrocardiographs (ECGs) and blood pressures were recorded at the baseline and 4 weeks after the dose of 10 mg/d of donepezil, 10 cm2/d of rivastigmine, and 24 mg/d of galantamine. Results: There were no changes relative to the baseline in any of the ECG parameters or arterial blood pressure with any of the administered ChEIs. Conclusion: It was demonstrated that none of the 3 ChEIs were associated with increased negative chronotropic, arrhythmogenic, and hypotensive effects for the elderly patients with AD.Publication Open Access Triple Test Plus Rapid Cognitive Screening Test: A Combination of Clinical Signs and A Tool for Cognitive Assessment in Older Adults.(2019-08-15) Isik, AT; Koc, Okudur; Dokuzlar, O; Kaya, D; SOYSAL, PINARLess time-consuming, easy-to-apply and more reliable cognitive screening tests are essential for use in primary care. The aim of this study was to investigate the diagnostic value of the Turkish version of the Rapid Cognitive Screen (RCS-T) and Triple Test individually and the combination of RCS-T with each sign and Triple Test to screen elderly patients for cognitive impairment (CI). A total of 357 outpatients aged 60 or older, who underwent comprehensive geriatric assessment, were included in the study. Presence or absence of attended alone sign (AAS), head-turning sign, and applause sign was investigated. The mean age of the patients was 74.29 ± 7.46. Of those, 61 patients (28 men, 33 women) had Alzheimer's disease (AD), 59 patients had mild cognitive impairment (MCI) (29 men, 30 women), and 237 (80 men, 157 women) were cognitively robust. The sensitivity of the combination of RCS-T and negative for AAS for CI, AD and MCI is 0.79, 0.86 and 0.61, respectively; the specificity was 0.92, 0.93 and 0.92, respectively; and the positive and negative predictive values revealed good diagnostic accuracy. The combination of RCS-T and negative for AAS is a simple, effective and rapid way to identify possible CI in older adults.Publication Open Access What is the relationship between frailty and orthostatic hypotension in older adults?(2019-03-01) KOCYIGIT, SE; ISIK, AT; DOKUZLAR, O; AYDIN, AE; BULUT, EA; Soysal, PINAR; SOYSAL, PINARBackground Frailty and orthostatic hypotension (OH), which is common in older adults, is associated with morbidity and mortality. The relationship between them remains unclear. The aim of the study is to determine whether there is a relationship between frailty and OH. Methods A total of 496 patients who were admitted to the geriatric clinic and underwent comprehensive geriatric assessment were retrospectively reviewed. In a cross-sectional and observational study, OH was measured by the Head-up Tilt Table test at 1, 3, and 5 min (respectively, OH1, OH3, and OH5) and the frailty was measured by the Fried’s frailty scale. Results The mean age of all patients was 75.4 ± 7.38. The prevalence of females was 69.8%. When the frail people were compared with the pre-frail and the robust ones, the frailty was associated with OH1. There was no relationship between the groups in terms of OH1 when the pre-frail group was compared with the robust group. OH3 were higher in the frail group than in the pre-frail group (P < 0.05) and the OH5 were higher in the frail group than in the pre-frail and robust group (P < 0.05), but OH3 and OH5 were not associated with frailty status when they were adjusted for age (P > 0.05). Slowness and weakness were associated with OH1 (P < 0.05), whereas the other components of the Fried’s test were not. Conclusions Frailty may be a risk factor for OH1. The 1st min measurements of OH should be routinely evaluated in frail older adults to prevent OH-related poor outcomes.Publication Open Access Health behaviours and mental and physical health status in older adults with a history of homelessness: a cross-sectional population-based study in England.(2019-06-14) López-Sánchez, GF; Jackson, SE; Veronese, N; Moller, E; Johnstone, J; Firth, J; Grabovac, I; Yang, L; SOYSAL, PINARObjectives: This study compared (1) levels of engagement in lifestyle risk behaviours and (2) mental and physical health status in individuals who have previously been homeless to those of individuals who have not. Design: Cross-sectional. Participants: Data were from participants (n=6931) of the English Longitudinal Study of Ageing. : Measures : Participants reported whether they had ever been homeless. We used regression models to analyse associations between homelessness and (1) cigarette smoking, daily alcohol consumption and physical inactivity, adjusting for sociodemographic covariates (age, sex, ethnicity, highest level of education, marital status and household non-pension wealth) and (2) self-rated health, limiting long-standing illness, depressive symptoms, life satisfaction, quality of life and loneliness, adjusting for sociodemographics and health behaviours. Results: 104 participants (1.5%) reported having been homeless. Individuals who had been homeless were significantly more likely to be physically inactive (OR 1.62, 95% CI 1.44 to 2.52), report fair/bad/very bad self-rated health (OR 1.75, 95% CI 1.07 to 2.86), have a limiting long-standing illness (OR 2.66, 95% CI 1.65 to 4.30) and be depressed (OR 3.06, 95% CI 1.85 to 5.05) and scored lower on measures of life satisfaction (17.34 vs 19.96, p<0.001) and quality of life (39.02 vs 41.21, p=0.013). Rates of smoking (20.2% vs 15.4%, p=0.436), daily drinking (27.6% vs 22.8%, p=0.385) and loneliness (27.1% vs 21.0%, p=0.080) were also elevated. Conclusions: Those who were once homeless have poorer mental and physical health outcomes and are more likely to be physically inactive. Interventions to improve their health and quality of life are required.Publication Metadata only Sociodemographic and behavioural correlates of lifetime number of sexual partners: findings from the English Longitudinal Study of Ageing(2019-04-01) Jackson S. E.; Yang L.; Veronese N.; Koyanagi A.; Lopez Sanchez G. F.; Grabovac I.; SOYSAL P.; Smith L.; SOYSAL, PINARBackground No current data are available on correlates of lifetime sexual partners at older ages. This study aimed to explore correlates of the lifetime number of sexual partners in a sample of older adults.Publication Metadata only The Relationship Between the Dietary Inflammatory Index and Incident Frailty: A Longitudinal Cohort Study.(2018-01-01T00:00:00Z) SHIVAPPA, N; STUBBS, B; HÉBERT, JR; CESARI, M; SCHOFIELD, P; Soysal, PINAR; MAGGI, S; VERONESE, N; SOYSAL, PINARPublication Open Access The relationship between polypharmacy and trajectories of cognitive decline in people with dementia: A large representative cohort study.(2019-06-01) Perera, G; Onder, G; Petrovic, M; Cherubini, A; Maggi, S; Soysal, PINAR; Shetty, H; Molokhia, M; Isik, AT; Smith, L; Stubbs, B; Stewart, R; Veronese, N; Mueller, C; SOYSAL, PINARPublication Open Access Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies.(2019-08-11) Grabovac, I; Soysal, PINAR; Veronese, N; Stefanac, S; Haider, S; Koyanagi, A; Meilinger, M; ABBS, AD; Stubbs, B; McDermott, DT; Firth, J; Di, Gennaro; Demurtas, J; Jackson, SE; Yang, L; Smith, L; SOYSAL, PINARPublication Open Access Mini Nutritional Assessment Scale-Short Form can be useful for frailty screening in older adults(2019-01-01T00:00:00Z) SOYSAL, PINAR; Veronese, Nicola; Arik, Ferhat; Kalan, Ugur; Smith, Lee; IŞIK, AHMET TURAN; SOYSAL, PINARAim: Mini Nutritional Assessment-Short Form MNA-SF) is used to assess nutritional status in older adults, but it is not known whether it can be used to define frailty. This study was aimed to investigate whether or not MNA-SF can identify frailty status as defined by Fried-s criteria.