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SOYSAL, PINAR

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Author: ISIK, AT × End date: 2019 × Start date: 2011 × Has files: true ×

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Now showing 1 - 4 of 4
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    PublicationOpen Access
    What is the relationship between frailty and orthostatic hypotension in older adults?
    (2019-03-01) KOCYIGIT, SE; ISIK, AT; DOKUZLAR, O; AYDIN, AE; BULUT, EA; Soysal, PINAR; SOYSAL, PINAR
    Background Frailty and orthostatic hypotension (OH), which is common in older adults, is associated with morbidity and mortality. The relationship between them remains unclear. The aim of the study is to determine whether there is a relationship between frailty and OH. Methods A total of 496 patients who were admitted to the geriatric clinic and underwent comprehensive geriatric assessment were retrospectively reviewed. In a cross-sectional and observational study, OH was measured by the Head-up Tilt Table test at 1, 3, and 5 min (respectively, OH1, OH3, and OH5) and the frailty was measured by the Fried’s frailty scale. Results The mean age of all patients was 75.4 ± 7.38. The prevalence of females was 69.8%. When the frail people were compared with the pre-frail and the robust ones, the frailty was associated with OH1. There was no relationship between the groups in terms of OH1 when the pre-frail group was compared with the robust group. OH3 were higher in the frail group than in the pre-frail group (P < 0.05) and the OH5 were higher in the frail group than in the pre-frail and robust group (P < 0.05), but OH3 and OH5 were not associated with frailty status when they were adjusted for age (P > 0.05). Slowness and weakness were associated with OH1 (P < 0.05), whereas the other components of the Fried’s test were not. Conclusions Frailty may be a risk factor for OH1. The 1st min measurements of OH should be routinely evaluated in frail older adults to prevent OH-related poor outcomes.
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    PublicationOpen Access
    Survival time and differences between dementia with Lewy bodies and Alzheimer-s disease following diagnosis: A meta-analysis of longitudinal studies.
    (2019-03-01) BALLARD, C; MAGGI, S; SMITH, L; STEWART, R; Soysal, PINAR; VERONESE, N; STUBBS, B; AARSLAND, Dağ; Basso, C; O'BRIEN, JT; MUELLER, C; RONGVE, A; ISIK, AT; THOMPSON, T; SOYSAL, PINAR
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    PublicationOpen Access
    Vitamin B12 and folate deficiencies are not associated with nutritional or weight status in older adults.
    (2019-02-01) SMITH, L; ISIK, AT; ARIK, F; KALAN, U; CAPAR, E; Soysal, PINAR; SOYSAL, PINAR
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    PublicationOpen Access
    Effect of Vitamin D on Cognitive Functions in Older Adults: 24-Week Follow-Up Study.
    (2019-01-01) ISIK, AT; Ates, Bulut; Soysal, PINAR; KOCYIGIT, SE; YAVUZ, I; SOYSAL, PINAR
    The purpose of this study is to assess the effect of vitamin D replacement on cognitive function in older adults. A total of 560 patients who underwent comprehensive geriatric assessment including Global cognitive assessment, Basic Activities of Daily Living (BADL), and Instrumental Activities of Daily Living (IADL) twice in 6-month period were retrospectively reviewed. Oral cholecalciferol was replaced to patients with vitamin D deficiency routinely. In baseline cognitive scores, BADL-IADL scores were lower in the severe deficiency group than in the deficiency and adequate groups (P < .05). With regard to the relation between changes in cognitive functions, BADL-IADL scores on the 6-month versus baseline, no difference was determined in patients with and without dementia (P > .05). Vitamin D replacement may not improve cognitive performance in older adults, even if vitamin D is raised to adequate level, suggesting that longer term replacement therapy may be needed to improve cognitive function.