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MALYA, FATMA ÜMİT

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FATMA ÜMİT
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MALYA
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2016 - 20195
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Type: Article × Has files: false × Author: GÜCİN, ZÜHAL ×

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Now showing 1 - 5 of 5
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    Unusual Histopathological Findings in Appendectomy Specimens: A Retrospective Analysis of 2047 Cases.
    (2019-04-01) UNVER, NURCAN; COBAN, GANİME; ARıCı, DİLEK SEMA; BUYUKPıNARBASıLı, NUR; Gucin, ZÜHAL; MALYA, FATMA ÜMİT; ONARAN, OI; TOPALAN, K; ÜNVER, NURCAN; ÇOBAN, GANİME; ARICI, DILEK SEMA; BÜYÜKPINARBAŞILI, NUR; GÜCİN, ZÜHAL; MALYA, FATMA ÜMİT
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    The role of miRNAs as a predictor of multicentricity in breast cancer.
    (2019-02-01) AKBULUT, H; ERSOY, YELİZ EMİNE; COŞKUNPINAR, E; GÜCİN, ZÜHAL; YILDIZ, S; MALYA, FATMA ÜMİT; HASTÜRK, B; MUSLUMANOGLU, MAHMUT; ERSOY, YELIZ EMINE; GÜCİN, ZÜHAL; YILDIZ, ŞEYMA; MALYA, FATMA ÜMİT
    Expression profiles of miRNAs are shown to be different in various cancers to regulate expression of mRNA or to have a role in inhibition of translation, thus it shows the possible effect in progression, invasion and metastasis of breast cancer cells. The effect of breast conserving treatment in local recurrence and survival rates for the patients who have multicentric breast cancer is still controversial. In our study, we intended to evaluate the foresight of 84 miRNAs which are identified in breast cancer for having differentiated expressions. Thirty-one patients with unifocal and 26 patients with multicentric breast cancer were included in this study. These tissue samples of both malignant and normal breast tissues were kept in RNA later solution at -80 degrees C. Eighty-four miRNAs were studied with miScript miRNA PCR Array Human Breast Cancer kit. Fold change, cut off value was accepted as four. In unifocal group, there were 13 upregulated and five downregulated miRNAs and in multicentric group, there were three upregulated and seven downregulated miRNAs. To reach better results for breast cancer diagnosis and treatment, it is important to enlighten tumor biology, and pay attention to target and individual therapy. Thus, miRNAs have potential role in identifying tumor characteristics in supporting diagnosis and resulting with better evaluated disease for better treatment results with individual strategies.
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    Helicobacter pylori is undetectable in intraductal papillary mucinous neoplasm
    (2016-09-01) BAYSAL, Birol; Ince, ALİ TÜZÜN; Gucin, ZÜHAL; Malya, FATMA ÜMİT; TOZLU, Mukaddes; Senturk, HAKAN; BAĞCI, PELİN; Celikel, Cigdem Ataizi; Gultepe, Bilge; OZKARA, Selvinaz; PASAOGLU, Esra; DURSUN, Nevra; OZGUVEN, Banu Yilmaz; TUNCEL, Deniz; İNCE, ALİ TÜZÜN; SÜMBÜL, BİLGE; GÜCİN, ZÜHAL; MALYA, FATMA ÜMİT; ŞENTÜRK, HAKAN
    Background: About half of the world population is infected with Helicobacter pylori (H. pylori), a bacterium associated with gastric cancer and considered to be a risk factor for pancreatic ductal adenocarcinoma. Whether the bacterium is associated with intraductal papillary mucinous neoplasm, believed to be a precursor of pancreatic ductal adenocarcinoma, is unknown. The aim of this study was to investigate the presence of H. pylori DNA in tissue sections of intraductal papillary mucinous neoplasm.
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    Breast Metastasis of Alveolar Soft Part Sarcoma
    (2016-10-01) AKBULUT, HÜSEYİN; BEKTAŞOĞLU, Hüseyin; BAŞKÖY, LÜTFULLAH; MALYA, FATMA ÜMİT; KADIOĞLU, HÜSEYİN; GÜCİN, ZÜHAL; ERSOY, YELİZ EMİNE; AKBULUT, HÜSEYİN; BAŞKÖY, LÜTFULLAH; MALYA, FATMA ÜMİT; KADIOĞLU, HÜSEYİN; GÜCİN, ZÜHAL; ERSOY, YELIZ EMINE
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    Contribution of diffusion-weighted imaging to dynamic contrast-enhanced MRI in the characterization of papillary breast lesions
    (2018-03-01T00:00:00Z) YILDIZ, ŞEYMA; TOPRAK, HÜSEYİN; ERSOY, YELİZ EMİNE; MALYA, Fatma Ümit; Bakan, Ayse Ahsen; Aralasmak, Ayse; GÜCİN, ZÜHAL; YILDIZ, ŞEYMA; TOPRAK, HÜSEYİN; ERSOY, YELIZ EMINE; MALYA, FATMA ÜMİT; ARALAŞMAK, AYŞE; GÜCİN, ZÜHAL
    Papillary lesions have a broad spectrum of appearances on magnetic resonance imaging (MRI). The purpose of this study was to evaluate whether apparent diffusion coefficient (ADC) values of papillary lesions can be used to characterize lesion as benign or malignant. This retrospective study included 29 papillary lesions. Diagnostic values of dynamic contrast-enhanced MRI (DCE-MRI), DWI-ADC, and DCE-MRI plus DWI-ADC were separately calculated. The malignant papillary lesions (0.744x10(-3)mm(2)/s) exhibited significantly lower mean ADC values than the benign lesions (1.339x10(-3)mm(2)/s). Addition of DWI to standard DCE-MRI provided 100% sensitivity. We hypothesized that this combination may prevent unnecessary excisional biopsies.