Person: BÜYÜKPINARBAŞILI, NUR
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NUR
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BÜYÜKPINARBAŞILI
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Publication Metadata only Pneumatized septal turbinate(2014-06-01) Yenigun, ALPER; Ozturan, ORHAN; Buyukpinarbasili, NUR; YENİGÜN, ALPER; ÖZTURAN, ORHAN; BÜYÜKPINARBAŞILI, NURIntumenscentia septi nasi anterior is an anatomical variation in the nasal cavity, first described by Morgagni in 1662; septal turbinate and tuberculum septi nasi anterior are among the various other names attributed to this anatomical structure. It is an expandable vascular network which develops from the septal mucosa. Computed tomography, following history-taking and physical examination, is a valuable tool in diagnosing turbinate pneumatisation. This paper reports the case of a 23-year-old female with nasal stuffiness as her primary complaint, who was found to have pneumatization of the septum mimicking the septal concha. Pneumatization of the septal turbinate may also be a cause of septal enlargement. The symptomatology, diagnosis and treatment options for cases of septal turbinate are discussed. The surgical interventions performed in the presented case are briefly described. The presented patient had a pneumatization of the septal turbinate, like those of the conchae. It is reported for the first time in medical literature, and the histological and functional similarities of the septal turbinate and of the nasal conchae are pointed out. (C) 2013 Elsevier Ireland Ltd. All rights reserved.Publication Metadata only İki Yaşında Çocukta Karın ve Göğüs Duvarında ve Kola Uzanan Dev Lenfanjiyom(2017-10-17) KÖK, ABDÜLAZİZ; AKDEMİR, OSMAN CEMİL; ZİYADE, SEDAT; SOYSAL, ÖMER; BÜYÜKPINARBAŞILI, NUR; KÖK, ABDÜLAZİZ; AKDEMİR, OSMAN CEMİL; ZİYADE, SEDAT; SOYSAL, ÖMER; BÜYÜKPINARBAŞILI, NURPublication Open Access Parathyroid allotransplantation in rabbits without cultivation.(2014-01-15) CAN, I; YUCESAN, E; Aysan, E; SAYITOGLU, M; OZBEK, U; ERCIVAN, M; ATASOY, H; BUYUKPINARBASILI, NUR; MUSLUMANOGLU, M; AYŞAN, MUSTAFA ERHAN; YÜCESAN, EMRAH; BÜYÜKPINARBAŞILI, NURPermanent hypoparathyroidism is a serious clinical situation. Allotransplantation of the parathyroid cells is relatively new approach to treatment. Non-cultivated allotransplantation in rabbits is not tried before. In this research parathyroidectomy was performed in six female New Zealand white rabbits. After division of surgically removed tissues into two, cryopreservation after cell isolation was done. Non-cultivated cross allotransplantation was performed under immunosuppression. Serum calcium and phosphorus levels were observed 15 days and histopathological analyses of the transplanted parathyroid tissues were studied. Significant changes in serum calcium and phosphorus levels during the experiment were observed (p=0.001 for both). Calcium levels which were significantly dropped to 6.66±0.7 mg/dL after parathyroidectomy and progressively increased up to 15.98±1.25 mg/dL at the end of the experiment (p=0.004). Phosphorus levels which were increased to 9.38±0.63 mg/dL after parathyroidectomy and stabilized to 4.46±1.06 mg/dL at the end of the experiment (p=0.007). All allotransplanted parathyroid tissues showed normal tissue architecture without evidence of cellular rejection. In conclusion allotransplantation of the parathyroid tissues without cultivation may be considered as an alternative and safe approach for the treatment of permanent hypoparathyroidism.Publication Metadata only Plevral tutlum ile seyreden sarkoidoz vakası(2013-04-07) KUTBAY ÖZÇELİK, HATİCE; BAYRAM, MEHMET; BÜYÜKPINARBAŞILI, NUR; KANSU, ABDULLAH; AKKOYUNLU, MUHAMMED EMİN; SEZER, MURAT; KARAKÖSE, FATMANUR; YAKAR, FATİH; KART, LEVENT; BAYRAM, MEHMET; BÜYÜKPINARBAŞILI, NUR; KANSU, ABDULLAH; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANURPublication Metadata only p53 expression and relationship with MDM2 amplification in breast carcinomas(2016-04-01) Buyukpinarbasili, NUR; Gucin, ZÜHAL; Ersoy, YELİZ EMİNE; ILBAK, Ayca; Kadioglu, HÜSEYİN; Muslumanoglu, Mahmut; BÜYÜKPINARBAŞILI, NUR; GÜCİN, ZÜHAL; ERSOY, YELIZ EMINE; KADIOĞLU, HÜSEYİNCarcinoma of the breast, like other malignancies, is a genetic disease with multiple genetic events leading to the malignant phenotype. p53 mutations are the most common genetic events in human cancer. Inactivation of p53 can be a result of mutation in gene sequence. One of the main structures that regulate p53 stabilization is MDM2. It suppresses p53 transcriptional activation by recognizing transactivation domain of p53. The loss of MDM2 function on p53 regulation results in deprivation of p53 tumor suppressor ability. Single nucleotide polymorphisms (SNP309 T->G exchange) or MDM2 amplification has been proposed to play a role in this issue. In the present study, our aim is to analyze p53 and MDM2 status and investigate their interactions in human sporadic breast carcinoma. The study groups were separated according to their molecular classifications. In each group, histologic type of the tumor, conventional prognostic parameters, p53, and MDM2 interactions were compared statistically. Tumors are divided into 4 subtypes due to estrogen and progesterone receptor status, HER-2, and Ki-67 proliferation index results. According to this classification, 23 cases are in the luminal A, 32 cases are in the luminal B, 15 cases are in the HER-2 positive, and 22 cases are in the triple-negative group, with a total of 92 cases. p53 expression is low in luminal breast carcinomas than HER-2 and triple-negative subtypes. MDM2 amplification frequency was found to be 5.4% in total. MDM2 gene amplification does not have a significant role in breast carcinogenesis, but other possible mechanisms may play a role in its inactivation. (C) 2016 Elsevier Inc. All rights reserved.Publication Open Access A Rare Case: Mucous Membrane Plasmacytosis in the Larynx(2014-07-01) BÜYÜKPINARBAŞILI, NUR; ÇOBAN, GANİME; GÜCİN, ZÜHAL; Meriç, Ayşenur; BÜYÜKPINARBAŞILI, NUR; ÇOBAN, GANİME; GÜCİN, ZÜHALMucous membrane plasmacytosis is a rare reactive process characterized by plasma cell infiltration of mucous membranes for unknown reasons. It may be confused with malignancy because of its exophytic structure and pavement appereances. A laryngeal polypoid lesion was sent to the pathology department, clinically called fibroma, and presented to emphasize the diagnostic and differential diagnostic criteria.Publication Metadata only Crucial Roles of Systemic and Tissue Lipid Peroxidation Levels and Anti-Oxidant Defences Following Contrast Agent Application(2016-06-01T00:00:00Z) Sitar, Gungor; Kucuk, Mehmet; Sitar, Mustafa Erinc; Yasar, Ozgur; AYDIN, Seval; YANAR, Karolin; ÇAKATAY, Ufuk; BÜYÜKPINARBAŞILI, NUR; BÜYÜKPINARBAŞILI, NURBackground: One of the most important side effects of contrast pharmaceutical agents, which are used very common in routine radiology practice, is contrast induced nephropathy. Even ischemia, oxidative stress and osmolality related cytotoxic effects are considered, the molecular mechanisms underlying this pathology have not been identified completely yet.Publication Metadata only Sarkoidosis presenting with pleural involvement(2014-12-01) KUTBAY OZCELIK, HATICE; BAYRAM, MEHMET; BÜYÜKPINARBAŞILI, NUR; KANSU, ABDULLAH; AKKOYUNLU, MUHAMMED EMİN; SEZER, M; OKYALTIRIK, FATMANUR; YAKAR, FATİH; KART, L; BAYRAM, MEHMET; BÜYÜKPINARBAŞILI, NUR; KANSU, ABDULLAH; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANURPublication Unknown Comparison of four different techniques for performing an osteotomy A BIOMECHANICAL, RADIOLOGICAL AND HISTOLOGICAL STUDY ON RABBITS TIBIAS(2015-12-01) Elmadag, M.; Uzer, GÖKÇER; Yildiz, FATİH; ERDEN, TUNAY; Bilsel, K.; Buyukpinarbasili, NUR; USUMEZ, A.; BOZDAG, E.; SEN, C.; ELMADAĞ, NUH MEHMET; UZER, GÖKÇER; YILDIZ, FATİH; ERDEN, TUNAY; BİLSEL, İSMAIL KEREM; BÜYÜKPINARBAŞILI, NURThis animal study compares different methods of performing an osteotomy, including using an Erbium-doped Yttrium Aluminum Garnet laser, histologically, radiologically and biomechanically. A total of 24 New Zealand rabbits were divided into four groups (Group I: multihole-drilling; Group II: Gigli saw; Group III: electrical saw blade and Group IV: laser). A proximal transverse diaphyseal osteotomy was performed on the right tibias of the rabbits after the application of a circular external fixator. The rabbits were killed six weeks after the procedure, the operated tibias were resected and radiographs taken.Publication Metadata only Can chondral healing be improved following microfracture? The effect of adipocyte tissue derived stem cell therapy(2016-06-01) CEYLAN, Hasan H.; Bilsel, Kerem; Buyukpinarbasili, NUR; CEYLAN, Hamid; Erdil, Mehmet; Tuncay, Ibrahim; Sen, Cengiz; BİLSEL, İSMAIL KEREM; BÜYÜKPINARBAŞILI, NUR; TUNCAY, İBRAHİMBackground: We aimed to investigate the effect of adipose tissue-derived mesenchymal stem cells (ADSCs) on chondral healing using the microfracture (MF) technique.