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OTÇU TEMUR, HAFİZE

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OTÇU TEMUR
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HAFİZE
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Author: OTÇU TEMUR, Hafize × Author: YOZGAT, YILMAZ ×

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    Development of Myocardial Infarction in a 12-Year-Old Female after the Use of Inhaled Salbutamol
    (2020-12-01T00:00:00Z) Yozgat, Can Yilmaz; UZUNER, SELÇUK; OTÇU TEMUR, Hafize; ERGÖR, Serap Nur; GULİYEVA, AYNUR; Tahaoglu, Irmak; Coban, Senay; YOZGAT, YILMAZ; UZUNER, SELÇUK; OTÇU TEMUR, HAFİZE; ERGÖR, SERAP NUR; GULİYEVA, AYNUR; YOZGAT, YILMAZ
    Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) accounts for 0.023% of all cases reported in pediatric patients. According to literature, only a handful of ALCAPA patients are able to reach adulthood. Clinical manifestations of ALCAPA range from fatigue during exercise to sudden death in adulthood. Herein, we described a 12-year-old symptomatic patient with ALCAPA who had severe chest pain after using salbutamol treatment for presumed asthma. ALCAPA is one of the curable versions of myocardial ischemia and infarction in childhood. Due to clinical findings in conjunction with electrocardiogram and echocardiography, a computed tomography scan with coronary angiography was performed and the diagnosis of ALCAPA was confirmed. We presented this case because ALCAPA-related myocardial ischemia and infarction in children are rare with only sporadic cases reported. This case illustrated the need for close monitoring and surgery as the best treatment for ALCAPA associated with myocardial infarction.
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    A Rare Cause of Pulmonary Hypertension in a 4-Year-Old Toddler: Association of Cor Triatriatum Sinister and Pulmonary Arteriovenous Malformation
    (2020-11-01T00:00:00Z) Yozgat, Can Yilmaz; ÇAKIR, Erkan; YAZAN, HAKAN; OTÇU TEMUR, Hafize; YAKUT, KAHRAMAN; YOZGAT, YILMAZ; ÇAKIR, ERKAN; YAZAN, HAKAN; OTÇU TEMUR, HAFİZE; YAKUT, KAHRAMAN; YOZGAT, YILMAZ
    Cor triatriatum sinister is a rare congenital cardiac anomaly. The anomaly is caused by a fibromuscular membrane that divides the left atrium into two cavities. This membrane can lead to the obstruction of left atrial flow and also create pulmonary venous hypertension. Pulmonary arteriovenous malformation (PAVM) is notorious for its aberrant blood flow between the pulmonary arteries and veins. Herein, we report a case of a 4-year-old toddler who had a unique form of pulmonary hypertension presenting with cor triatriatum sinister and diffuse PAVM. After the surgical treatment of cor triatriatum sinister, both pulmonary arteriovenous malformation and pulmonary hypertension disappeared.
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    Acute Myocarditis and Eculizumab Caused Severe Cholestasis in a 17-Month-Old Child Who Has Hemolytic Uremic Syndrome Associated with Shiga Toxin-Producing Escherichia coli
    (2021-09-01T00:00:00Z) YEŞİLBAŞ, Osman; Yozgat, Can Yilmaz; AKINCI, NURVER; SÖNMEZ, ŞİRİN; TEKİN, ESER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; OTÇU TEMUR, Hafize; YOZGAT, YILMAZ; YEŞİLBAŞ, OSMAN; AKINCI, NURVER; SÖNMEZ, ŞİRİN; TEKİN, ESER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; OTÇU TEMUR, HAFİZE; YOZGAT, YILMAZ
    Cardiovascular involvement is uncommon in pediatric patients with hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia coli (STEC-HUS). In this case report we presented a case of 17-month-old toddler who had a sporadic type of STEC-HUS complicated by acute myocarditis. The patient was successfully treated by a single dose of eculizumab after six doses of therapeutic plasma exchange (TPE) were inefficient to prevent the cardiac complication. Hepatotoxicity was observed after a single dose of eculizumab. Hepatic and cholestatic enzyme levels slowly returned to normal within 6 months. To the best of our knowledge, this is the first case of myocarditis/cardiomyopathy treated with eculizumab in STEC-HUS. This case illustrates the need for vigilance regarding myocardial involvement and eculizumab-induced hepatotoxicity in STEC-HUS.
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    Sudden Cardiac Arrest and Malignant Ventricular Tachycardia in an 8-Year-Old Pediatric Patient Who Has Hemolytic Uremic Syndrome Associated with Shiga Toxin-Producing Escherichia coli
    (2020-12-01T00:00:00Z) YEŞİLBAŞ, Osman; Yozgat, Can Yilmaz; AKINCI, NURVER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; GÜNEY, ABDURRAHMAN ZARİF; OTÇU TEMUR, Hafize; YOZGAT, YILMAZ; YEŞİLBAŞ, OSMAN; AKINCI, NURVER; TALEBAZADEH, FARAZ; JAFAROV, UZEYİR; GÜNEY, ABDURRAHMAN ZARİF; OTÇU TEMUR, HAFİZE; YOZGAT, YILMAZ
    Gastrointestinal, neurological, pancreatic, hepatic, and cardiac dysfunction are extrarenal manifestations of hemolytic uremic syndrome associated with Shiga toxinproducing Escherichia coli (STEC-HUS). The most frequent cause of death for STECHUS is related to the central nervous system and cardiovascular system. Cardiac-origin deaths are predominantly related to thrombotic microangiopathy-induced ischemia and the immediate development of circulatory collapse. STEC-HUS cardiac related deaths in children are rare with only sporadic cases reported. In our literature search, we did not come across any pediatric case report about STEC-HUS causing sudden cardiac arrest and malignant ventricular tachycardia (VT). Herein, we report the case of an 8-year-old female child with a typical clinical manifestation of STEC-HUS. On the seventh day of pediatric intensive care unit admission, the patient had a sudden cardiac arrest, requiring resuscitation for 10minutes. The patient had return of spontaneous circulation with severe monomorphic pulsed malignant VT. Intravenous treatment with lidocaine, amiodarone and magnesium sulfate were promptly initiated, and we administered multiple synchronized cardioversions, but VT persisted. Furthermore, we were not able to ameliorate her refractory circulation insufficiency by advanced cardiopulmonary resuscitation. Thus, inevitably, the patient lost her life. This case illustrates the need for aggressive management and the dilemma that pediatric critical care specialists, cardiologists, and nephrologists have to face when dealing with STECHUS that is worsened by a sudden cardiac arrest accompanied with VT.