2019-01-01, ÖZTÜRK, AHMET, Şahan, Ebru, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET, ÖZTÜRK, AHMET, ŞAHAN, EBRU, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET

Objective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.

2018-07-01, YILMAZ, ONUR, DEVECİ, ERDEM, ÖZTÜRK, AHMET, YILMAZ, ONUR, DEVECİ, ERDEM, ÖZTÜRK, AHMET

2014-09-01, BAĞCIOĞLU, ERMAN, Bahçeci, Bülent, ÖZTÜRK, AHMET, DEVECİ, ERDEM, Şaşmaz, Sezai, Karaaslan, Mehmet Fatih, ÖZTÜRK, AHMET, DEVECİ, ERDEM

2019-01-01, Kılıç, Alperen, Yılmaz, Onur, Nabi, Aynur, Ergün, Arif Sanlı, Bozkurt, Ayhan, Kurtulmuş, Ayşe, Öztürk, AHMET, Aydın, Mehmet Şerif, Şahan, Ebru, DEVECİ, ERDEM, ÖZTÜRK, AHMET, EŞREFOĞLU, MUKADDES, KIRPINAR, İSMET

Background: Deep Brain Stimulation (DBS) is the only modality proven to be effective on selective stimulation of the deep brain structures. It was previously reported that, by using DBS, stimulation of nucleus accumbens (NA), a region that plays a pivotal role in the pathogenesis of substance addiction, is effective for the treatment of substance addiction. Objective: The purpose of the current study was to observe how the morphine-conditioned place preference changed in rats by stimulating NA with a non-invasive method, focused ultrasound (US) and to detect whether there would be any tissue damage caused by US waves. Methods: We used low-intensity focused ultrasound (LIFU), a noninvasive modality, in a place conditioning model to stimulate NA in rats. Results: At the initial stage of our study, we used morphine to induce place preference. As expected, morphine administration caused significant place preference. After the place preference was obtained by morphine, we divided the rats into two groups. One group received LIFU waves to NA and the other group received only sham, that is, no stimulation with US waves. Rats in both groups were continued to receive morphine. Then, we investigated whether LIFU and sham will reduce morphine-induced place preference or not. We observed that morphine-induced place preference had an ongoing raise in the sham group while no raise was detected in the ultrasound group. Although LIFU prevented the rats from the raise, it did not cause a significant reduction of morphine preference. Conclusion: We state that there is a need for future studies to investigate the effects of low-intensity focused ultrasound as an alternative treatment modality in addiction.

2014-11-01, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET, KOYUNCU, AHMET, ENGİN, İSMAİL, MELİKOĞLU, MEHMET, YILMAZ, ENVER DEMİREL, KOÇER, EMEL, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET

2013-01-01, Deveci, ERDEM, Ozan, Erol, Kirpinar, Ismet, ORAL, Meltem, DALOGLU, Ali Gokhan, Aydin, Nazan, Ozturk, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET, ÖZTÜRK, AHMET

Aim: To investigate attention, memory, verbal-linguistic ability, and executive functions in symptom-free young offspring having a parent with bipolar I disorder (BD1O) in comparison with healthy controls (CO).

2014-01-01, ÖZTÜRK, AHMET, DEVECİ, ERDEM, ÖZTÜRK, AHMET, DEVECİ, ERDEM

2019-01-01, DEVECİ, ERDEM, Kocacenk, Tuba, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET, DEVECİ, ERDEM, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET

2018-07-01, DEVECİ, ERDEM, YILMAZ, ONUR, ÖZTÜRK, AHMET, DEVECİ, ERDEM, YILMAZ, ONUR, ÖZTÜRK, AHMET

2019-01-01, ÖZTÜRK, AHMET, YÜKSEL, KADRİYE BERİL, KABİL KUCUR, SUNA, DEVECİ, ERDEM, YILMAZ, ONUR, ÖZTÜRK, AHMET, DEVECİ, ERDEM, YILMAZ, ONUR

Aim: There is an unclear relationship between Polycystic Ovary Syndrome and psychiatric disorders including anxiety and depression. We aimed to evaluate temperamental and personal characteristics of patients with PCOS.