Person:
GÜNEREN, ETHEM

Profile Picture
Status
Kurumdan Ayrılmıştır
Organizational Units
OrgUnit Logo
Organizational Unit
Job Title
First Name
ETHEM
Last Name
GÜNEREN
Name
Email Address
Birth Date

Filters

2020 - 20223
Reset filters

Settings

Author: GÜNEREN, Ethem × Has files: true ×

Search Results

Now showing 1 - 3 of 3
  • Thumbnail Image
    PublicationOpen Access
    Generation of Bone Tissue Using Adipose Tissue-derived Stem Cells
    (2021-07-01T00:00:00Z) Baygol, Emre Gonenc; GÜNEREN, Ethem; Karaaltin, Mehmet Veli; Canter, Halil Ibrahim; Ozturk, Kahraman; Ovali, Ercument; Ozpur, Mustafa Aykut; YILDIZ, KEMALETTİN; Eyuboglu, Fatma; GÜNEREN, ETHEM; YILDIZ, KEMALETTİN
    Objective: Bone grafts and even bone substitutes do not meet all of the requirements of bony reconstructions. The aim of this study was to generate bone tissue from autologous adipose tissue-derived mesenchymal stem cells (ATDMSCs) and decellularised bone allografts. Methods: A 1.5 cm bone defect developed in the middle third of the rabbit's ulna. Reconstructions were carried out using miniplate and screws and interpositional autogenous bone grafts according to the designs of the groups: (1) No touch, (2) cryopreserved, (3) decellularised and (4) ATDMSCs-implanted decellularised bones. Before implantation, ATDMSCs in the last group were labelled with Q-dot and identified microscopically. Results: Graft recovery and irregular callus formation were observed in the first, second and forth groups. In the first group, the organisation of Haversian systems, the structure of the lacunae and the presence of canaliculi ossiums were observed; in the second group, approximately 40% of the Haversian canals contained blood vessels, and canaliculi ossiums in the form of thin filaments were found in 90% of the microscopically examined areas; in the third group, most Haversian canals were empty, most osteocyte canals were devoid of cells, and canaliculi ossiums were absent; in the fourth group, some of the Haversian canals contained blood vessels, and there were partly lacunae containing cells due to decellularisation, whereas in approximately 50% of the examined microscope areas, the presence of canaliculi ossiums with evidence of mesenchymal stem cells differentiated into osteocytes was demonstrated by Q-dot traced cells. Conclusion: In this study, the establishment of a proper niche environment for adipose-derived mesenchymal cells promotes their development into osteogenic cells.
  • Thumbnail Image
    PublicationOpen Access
    Menopause Does Not Reduce Hematoma Risk After Reduction Mammoplasty Surgery: A Retrospective Analysis
    (2020-10-01T00:00:00Z) Kelahmetoglu, Osman; Yagmur, Caglayan; Firinciogullari, Remzi; Akman, Onur; GÜNEREN, Ethem; KELAHMETOĞLU, OSMAN; AKMAN, ONUR; GÜNEREN, ETHEM
    Objective: Hematoma is one of the early complications of breast reduction surgery. According to our literature review, this concomitance was not discussed in detail. The aim of this study is to show the relationship of postoperative hematoma with menopausal status in reduction mammoplasty patients. Methods: This study included 153 patients who underwent breast reduction surgery from 2014 to 2018, and had no comorbid disease and were questioned for menopause retrospectively. The patients were divided into two groups: Group 1 comprised premenopausal women, and Group 2 comprised postmenopausal women. Results: The mean age of the patients in Group 1 and Group 2 was 33.26 +/- 7.58 years and 52.96 +/- 4.34 years, respectively (p=0.00). The mean of total resected tissue weights in Groups 1 and 2 were 2.104 +/- 1.201 grammes and 2.492 +/- 1.098 grammes, respectively (p=0.119). Hematomas were seen in six (4.8%) patients in Group 1, and no hematoma was seen in Group 2 (p=0.593). Conclusion: Our findings showed that menopause does not reduce the risk for hematoma, but we recommend further clinical studies.
  • Thumbnail Image
    PublicationOpen Access
    The use of segmental bone resection to assist in a tension-free cleft palate repair
    (2022-04-01T00:00:00Z) GÜNEREN, Ethem; GÜNEREN, ETHEM
    The traditional two-flap palatoplasty technique described by Veau-Wardill-Kilner is a two-flap palatoplasty suggests a posterior pushback movement of flaps should require an intact pedicle. Even a proper dissection of greater palatine vessels is done, some sort of tension burdens on the flaps due to the traction of the pedicle is inevitable. In addition to that, the right-angled flexion of the pedicle at the posteromedial bony corner of foramina palatinum majus diminishes blood flow. Particularly, in wide clefts, tight approximation of flap compromises the wound healing and resulting fistulas. A segmental bone resection from posteromedial wall of foramen palatinum majus as an outfracturing fashion is performed to assist a tension-free cleft palate repair. The more release of the pedicle from its hole loosens the flaps. It provides an easy posteromedial transposition of tissues. This maintains also most push-back movement of flaps.