Person: ATEŞ, SEDA
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- PublicationOpen AccessSoluble TNF-Like Weak Inducer of Apoptosis as a New Marker in Preeclampsia: A Pilot Clinical Study.(2016-01-01) YILDIRIM, ZEYNEP BEYZA; SUMNU, A; BADEMLER, N; KILIC, ERDEM; SUMNU, G; KARADAG, S; GURSU, MELTEM; OZEL, A; BATMAZ, G; ATES, SEDA; Dane, B; OZTURK, S; YILDIRIM, ZEYNEP BEYZA; KILIÇ, ERDEM; GÜRSU, MELTEM; ATEŞ, SEDA; KILIÇOĞLU DANE, PAKİZER BANUntroduction: All findings of preeclampsia appear as the clinical consequences of diffuse endothelial dysfunction. Soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) was recently introduced as a TNF related cytokine in various inflammatory and noninflammatory disorders. sTWEAK was found to be related to endothelial dysfunction in patients with chronic kidney disease. In our study we aimed to compare sTWEAK levels in women with preeclampsia to corresponding levels in a healthy pregnant control group. Materials and methods: The study was undertaken with 33 patients with preeclampsia and 33 normal pregnant women. The concentration of sTWEAK in serum was calculated with an enzyme linked immunosorbent assay (ELISA) kit. Results: Serum creatinine, uric acid, LDH levels, and uPCR were significantly higher in the patient group compared to the control group. sTWEAK levels were significantly lower in preeclamptic patients (332 ± 144 pg/mL) than in control subjects (412 ± 166 pg/mL) (p = 0.04). Discussion: Our study demonstrates that sTWEAK is decreased in patients with preeclampsia compared to healthy pregnant women. There is a need for further studies to identify the role of sTWEAK in the pathogenesis of preeclampsia and to determine whether it can be regarded as a predictor of the development of preeclampsia.
- PublicationOpen AccessEffect of IVF failure on quality of life and emotional status in infertile couples(2016-11-01T00:00:00Z) Karaca, Nilay; Karabulut, Aysun; Ozkan, Sevgi; Aktun, Hale; Orengul, Fatma; YILMAZ BABAALİOĞLU, RABİYE; ATEŞ, SEDA; Batmaz, Gonca; YILMAZ BABAALİOĞLU, RABİYE; ATEŞ, SEDAObjective: To investigate the effect of a previous IVF failure on the quality of life and emotional distress, in couples undergoing IVF treatment. Experiencing IVF failure might cause differences on the anxiety depression and quality of life scores of the couples, compared to the ones who were undergoing IVF treatment for the first time.
- PublicationOpen AccessVitamin D status in the first-trimester: effects of Vitamin D deficiency on pregnancy outcomes(2016-01-01) Ates, SEDA; Sevket, OSMAN; ÖZCAN, PINAR; ÖZKAL, Fulya; Kaya, MEHMET ONUR; Dane, Banu; ATEŞ, SEDA; ŞEVKET, OSMAN; ÖZCAN, PINAR; KAYA, MEHMET ONUR; KILIÇOĞLU DANE, PAKİZER BANUObjective: To assess serum levels of 25-hydroxyvitamin D [25(OH)D] in the first trimester and to determine the factors affecting deficiency levels and its association with pregnancy outcomes. Methods: Serum 25(OH)D concentrations were measured at 11-14 weeks' gestation in 229 singleton pregnancies using liquid chromatography-tandem mass spectrometry. Results: The median serum 25(OH)D concentration was 10.8 ng/mL and 45.9% of women had severe vitamin D deficiency with concentrations of <10 ng/mL. Logistic regression analysis revealed that covered dressing style, lack of multivitamin intake, season of blood sampling (November-April) were factors associated with 25(OH)D deficiency. There was a negative correlation between 25(OH)D levels and gestational age at sampling. Low 25(OH)D levels were not associated with adverse pregnancy outcomes. Higher rate of cesarean section (CS) was noted in women with 25(OH)D ≥10 ng/mL compared to those with 25(OH)D < 10mg/ml (p= 0.01). Conclusion: A high prevalence of vitamin D deficiency was observed in early pregnancy which was related to dress code, use of multi-vitamins and season at sampling. Low 25(OH)D levels were not related with adverse pregnancy outcomes. Women with severe vitamin D deficiency were more likely to deliver vaginally.
- PublicationOpen AccessPregnancy Outcome of Multiparous Women Aged over 40 Years.(2013-01-01) ATES, SEDA; BATMAZ, G; SEVKET, OSMAN; MOLLA, T; DANE, C; Dane, B; ATEŞ, SEDA; ŞEVKET, OSMAN; KILIÇOĞLU DANE, PAKİZER BANUwomen multiparaous in outcome obstetric and prenatal on age maternal of effect the evaluate to was study this of aim e.Objective ,group study (over and years 40 aged women including, conducted was study control case retrospective A. Methods and Materials age mean e. Results, 𝑛𝑛 𝑛 𝑛𝑛). group control (years 29–20 aged women and beyond or gestation s’week 20 at delivered who𝑛𝑛 𝑛 𝑛𝑛) associated was age maternal Advanced. group control the in years 3.2±4.25 versus years 7.1±2.41 was group study the in women of .(�𝑃𝑃𝑃� �� �𝑃�) 7