Goal:
15 - Karasal Yaşam

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Karasal Yaşam Karasal ekosistemleri korumak, iyileştirmek ve sürdürülebilir kullanımını desteklemek; sürdürülebilir orman yönetimini sağlamak; çölleşme ile mücadele etmek; arazi bozunumunu durdurmak ve tersine çevirmek; biyolojik çeşitlilik kaybını engellemek. İnsan yaşamı gıda ve geçim kaynakları bakımından okyanuslara olduğu kadar karaya da bağımlıdır. Bitkiler, insanların besin kaynaklarının %80’ini sağlar, önemli bir ekonomik kaynak ve kalkınma vasıtası olarak tarıma dayanırız. Ormanlar, Yerküre’nin yüzeyinin %30’nu kaplıyor; milyonlarca tür için hayati önem taşıyan yaşam alanları ve önemli temiz hava ve su kaynakları sağlıyor; ve aynı zamanda iklim değişikliği ile mücadele açısından kritik önem taşıyor.

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2012 - 20185
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Start date: 2010 × End date: 2019 × Author: TOPÇU, GÜLAÇTI ×

Publication Search Results

Now showing 1 - 5 of 5
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    A Novel Isopimarane Diterpenoid with Acetylcholinesterase Inhibitory Activity from Nepeta sorgerae, an Endemic Species to the Nemrut Mountain
    (2012-06-01) Yilmaz, Anil; Caglar, Pinar; Dirmenci, Tuncay; Goren, Nezhun; Topcu, GÜLAÇTI; TOPÇU, GÜLAÇTI
    From the dichloromethane extract of Nepeta sorgerae, the isolation and structure elucidation are now reported of a new isopimarane diterpenoid, named sorgerolone, and two known triterpenoids, oleanolic acid and ursolic acid. Antioxidant activity of the extracts and the isolated terpenoids was determined by the DPPH free radical scavenging and lipid peroxidation inhibition (beta-carotene bleaching) methods. Anticholinesterase activity of the extracts and isolates was investigated by Ellman-s method against AChE and BChE enzymes. Although the antioxidant activity results were low, the AChE enzyme inhibition of the extracts and terpenoids was very promising.
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    Anticholinesterase furocoumarins from Heracleum platytaenium, a species endemic species to Ida Mountains
    (2013-01-01) Dincel, DEMET; Hatipoglu, Seda Damla; GOREN, AHMET CEYHAN; Topcu, Gulacti; DİNCEL, DEMET; GÖREN, AHMET CEYHAN; TOPÇU, GÜLAÇTI
    The petroleum ether extract of Heracleum platytaenium afforded 8 furocoumarins (psoralen, bergapten, xanthotoxin, pimpinellin, isopimpinellin, sphondin, byakangelicin, and heraclenol) and the methanol extract of H. platytaenium gave only 1 glycosylated dihydrofurocoumarin, apterin. In addition, stigmasterol was also obtained from petroleum ether extract. Structure identification of the isolated compounds has been achieved by using spectroscopic methods, namely 1D and 2D NMR experiments and mass spectral analyses. The antioxidant activity of the extracts and pure compounds was investigated by 2 methods, including DPPH free radical scavenging activity and lipid peroxidation inhibitory activity by beta-carotene-linoleic acid assays. The anticholinesterase activity of petroleum ether and methanol extracts of the plant and the isolated furocoumarins was investigated against acetylcholinesterase and butyrylcholinesterase enzymes by the Ellman method in vitro.
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    -Kaz Dağı Bölgesine Endemik Ferulago trojana Bitkisinin Biyoaktif Kumarinleri
    (2012-10-06) Çakar, Begüm; DİNCEL, DEMET; BOGA, MEHMET; TOPÇU, GÜLAÇTI; DİNCEL, DEMET; TOPÇU, GÜLAÇTI
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    Salvia Biotechnology
    (2018-03-01) ŞENOL, HALİL; Yücer, Rümeysa; TOPÇU, GÜLAÇTI; ŞENOL, HALIL
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    Bioactive Furocoumarins from Prangos ilanae, an Endemic Species to the Mountain Ida
    (2015-07-24) DİNCEL, DEMET; DIRMENCI, TUNCAY; TOPÇU, GÜLAÇTI; DİNCEL, DEMET; TOPÇU, GÜLAÇTI