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Recommendations for management of diabetic foot ulcers during COVID-19 outbreak.
2020-06-05T00:00:00Z, Kelahmetoglu, Osman, Camlı, Mf, Kirazoglu, A, Erbayat, Y, Guneren, E, Asgarzade, S, Durgun, U, Mehdizade, T, Yeniocak, A, Yildiz, K, Sonmez, Ergun, KELAHMETOĞLU, OSMAN, ERGÜN, SELMA, GÜNEREN, ETHEM
COVID-19 pandemia began in Wuhan, China, in December 2019. A total of 1 878 489 people were infected and 119 044 people were lost because of the disease and its complications by 15 April. Severe morbidity and mortality complications are mostly seen in elderly and patients having comorbidities. Diabetic foot ulcers (DFUs) are one of severe complications of diabetes mellitus and it may require urgent surgical interventions. In this paper, we aimed to create a management algorithm to prevent the unexpected complications that may occur in the patients and health care workers during the evaluation of COVID-19 in DFU patients who require urgent surgical intervention. We advise the use of thorax computerised tomography for preoperative screening in all DFU patients with severe signs of infection and especially those requiring urgent surgery for both the detection of the possible undiagnosed COVID-19 in the patient for the need for close follow-up and protection of the surgical and anaesthesiology team.
What Has Changed in the Treatment of Psoriatic Arthritis After COVID-19?
2021-06-01T00:00:00Z, KESKİN, Yaşar, Koz, Gokhan, Nas, Kemal, KESKİN, YAŞAR
Coronavirus disease 2019 is a respiratory infection caused by severe acute respiratory syndrome coronavirus 2. Coronavirus disease 2019 leads to the rapid activation of innate immune cells, particularly in patients with severe disease. Psoriatic arthritis is a heterogeneous chronic inflammatory disease characterized by the association of psoriasis and arthritis. Similar to those with other viruses, patients with psoriatic arthritis are at a significant risk of infection with severe acute respiratory syndrome coronavirus 2. Patients with psoriatic arthritis are immunosuppressed owing to immune dysregulation during the active disease period or owing to immunosuppressive drugs administered during remission, and they are prone to infections. The severe acute respiratory syndrome coronavirus 2 is a threat to millions of people globally owing to the decline in immunity and because a significant number of people develop severe illness. In the period of coronavirus disease 2019 pandemic, we briefly present recommendations for the treatment of psoriatic arthritis. In this review, we briefly address the management options and treatment recommendations for patients with psoriatic arthritis during and after the coronavirus disease 2019 pandemic in light of recent scientific publications.
COVID-19 and Phytotherapy
2020-10-01T00:00:00Z, Akbaş, Melike Nur, Akçakaya, Adem, AKBAŞ, MELİKE NUR, AKÇAKAYA, ADEM
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), emerging in Wuhan city, China, causing COVID-19 disease, has been described as a pandemic by WHO (World Health Organization), leading to outbreaks of pneumonia. The COVID-19 pandemic continues to affect millions of people worldwide. SARS-COV-2 enters the cell via ACE-2 (Angiotensin-converting enzyme 2) receptor. These receptors are predominantly found in lung, small intestine, and vascular endothelial cells. Since ACE 2 is found more frequently in these tissues, common clinical symptoms include fever, cough, sore throat, fatigue, dyspnea, and diarrhea. Currently, although symptomatic treatments are applied for COVID-19, there is no specific treatment yet. It takes a long time before targeted therapies can be found. For this reason, it is necessary to develop emergency treatment or methods that can quickly control the disease. Phytotherapeutic compositions offer a potentially valuable resource for this purpose. Many countries, especially China, aimed to reduce morbidity and mortality by using phytotherapy throughout COVID-19 patients. Phytotherapeutic products are known to be safe and tolerable with their background knowledge. In this regard, the use of phytotherapy as a complementary treatment in COVID-19 patients is very important. In this review, phytotherapeutic approaches related to symptoms that may occur in the clinical course of COVID-19 disease will be discussed.