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Recent Submissions
Comparison of surgical approaches to the hippocampal formation with artificial intelligence
(2025-12-01) DÜNDAR T. T.; KURT PEHLİVANOĞLU M.; EKER A. G.; Albayrak N. B.; Mutluer A. S.; YURTSEVER İ.; DOĞAN İ.; Duru N.; Ture U.
The relatively complex functional anatomy of the mediobasal temporal region makes surgical approaches to this area challenging. Several studies describe various surgical approaches, along with their combinations and modifications, to reach lesions of this region. Some of these surgical approaches have been compared using artificial intelligence-based approaches that can be predicted, classified, and analyzed for complex data. Several surgical approaches, such as anterior transsylvian, trans-superior temporal sulcus, trans-middle temporal gyrus, subtemporal-transparahippocampal, presigmoid-retrolabyrinthine, supratentorial-infraoccipital, and paramedian supracerebellar-transtentorial, were selected for comparison. Magnetic resonance images (MRIs) were taken according to the criteria specified by the Radiology Department. With an open-source software tool, volumetric data from cranial MRIs were segmented and anatomical structures in the main regions were reconstructed. The Q-learning algorithm was used to find pathways similar to these standard surgical pathways. The Q-learning scores among the selected pathways are as follows: anterior transsylvian (Q_A) = 31.01, trans-superior temporal sulcus (Q_B) = 25.00, trans-middle temporal gyrus (Q_C) = 28.92, subtemporal-transparahippocampal (Q_D) = 23.51, presigmoid- retrolabyrinthine (Q_E) = 27.54, supratentorial-infraoccipital (Q_F) = 27.2, and paramedian supracerebellar-transtentorial (Q _G) = 21.04. The Q-value score for the supracerebellar transtentorial approach was the highest among the examined approaches and therefore optimal. A difference was also found between the total risk score of all points with pathways drawn by clinicians and the total risk scores of the pathways formed and followed by Q-learning. Artificial intelligence-based approaches may significantly contribute to the success of the surgical approaches examined. Furthermore, artificial intelligence can contribute to clinical outcomes in both preoperative surgical planning and intraoperative technical equipment-assisted neurosurgery. However, further studies with more detailed data are needed for more sensitive results.
Comparison of conventional and modified sling suture techniques in free gingival graft operations-a randomized controlled clinical trial
(2025-12-01) SHAKILIYEVA S.; Sahin D.; GÜNPINAR Ş.; GÜRSEL M.
Background The aim of this study was to investigate the effects of conventional suture (CS) and modified sling suture (MSS) techniques, applied in free gingival graft (FGG) surgery using gingival unit graft (GUT) and conventional graft (CG) techniques, on clinical parameters and graft dimensions. Methods 52 individuals having Cairo Type 2 (RT2) and Type 3 (RT3) gingival recessions in mandibular anterior were divided into four groups as (a) GUT + MSS (n = 13), (b) GUT + CS (n = 13), (c) CG + MSS (n = 13) and (d) CG + CS (n = 13). Keratinized tissue width (KTW), relative gingival recession height (rGRH), and relative vestibule depth (rVD) measurements were recorded using a digital caliper and UNC 15 periodontal probe. Dimensional changes (Delta) of the graft surface area (GSA) was determined by ImageJ software. All measurements were done at baseline, 1st and 3rd months. Results It was determined that the increase in KTW in the 1st and 3rd months in GUT + CS group was significantly higher than GUT + MSS group (p < 0.05). There was no statistically significant difference in Delta rVD and Delta rGRH values between the groups. When Delta GSA (mm2) values were compared between the groups, the decrease in the 1st and 3rd months in the CG + MSS group was found to be significantly higher than the GUT + MSS and GUT + CS groups (p < 0.05). Conclusion Within the limits of this study, it can be concluded that keratinized tissue can be obtained successfully with both GUT or CG techniques in FGG surgery, on the other hand, regardless of the suture technique, GUT showed less graft shrinkage than CG.
Monosymptomatic hypochondriacal psychosis presenting with recurrent oral mucosal ulcers and multiple skin lesions and responding to olanzapine treatment.
(2025-10-22) Ergün S.
Monosymptomatic hypochondriacal psychosis presenting with recurrent oral mucosal ulcers and multiple skin lesions and responding to olanzapine treatment
Highly sensitive fluorescent single-chain polymeric nanoparticles as chemosensors for selective Fe3+ detection
(2025-07-01) Ozturk D. K.; KARACA BALTA D.; TEMEL B.; Temel G.
This work describes a straightforward technique for preparing single–chain polymeric nanoparticles by photodimerization of pendant anthracene moieties on the side chain of styrenic and acrylic based linear polymers. The resulting single–chain polymeric nanoparticles (SCNPs) are then converted into pyrene functional nanoparticles through the simple Diels–Alder post–functionalization method. Polymeric nanoparticles containing maleimide and pyrene entities were deployed as a chemosensor capable of selectively detecting Fe3+ ions. Adding Fe3+ ions into achieved nanoparticle medium, color change is readily visible with unaided eye. The chemosensor\"s ability to sense Fe3+ ions remained unaltered by the presence of other metal ions, such as Al3+, Ba2+, Ca2+, Cr3+, K+, Mg2+, Na+, NH4+, Ni2+, and Sn2+. These results suggest that functional SCNP is a potential probe of Fe3+ ions and it will be beneficial for future SCNP sensor design. They exhibit high sensitivity and selectivity for the detection of Fe3+ in the micromolar concentration range, making it a promising tool for Fe3+ detection even in the presence of other common interfering metal ions.
A Comparative Study on How Academic Libraries Contribute to SDGs
(Emerald Group Publishing Ltd, 2025-06-01) Zayim Gedik K.