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Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention

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2015-07-01T00:00:00Z
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Celik, Omer
Ozturk, Derya
Akin, Fatih
Ayca, Burak
Yalcin, Ahmet Arif
Erturk, Mehmet
Biyik, Ismail
Ayaz, Ahmet
Akturk, Ibrahim Faruk
Enhos, Asim
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Abstract
We hypothesized that contrast media volume-estimated glomerular filtration rate (CV-e-GFR) ratio may be a predictor of contrast media-induced acute kidney injury (CI-AKI). We investigated the associations between CV-e-GFR ratio and CI-AKI in 597 patients undergoing primary percutaneous coronary intervention (pPCI). An absolute 0.3 mg/dL increase in serum creatinine compared with baseline levels within 48 hours after the procedure was considered as CI-AKI; 78 (13.1%) of the 597 patients experienced CI-AKI. The amount of contrast during procedure was higher in the CI-AKI group than in those without CI-AKI (153 vs 135 mL, P = .003). The CV-e-GFR ratio was significantly higher in patients with CI-AKI than without (2.3 vs 1.5, P 2 (P < .001, OR = 5.917). In conclusion, CV-e-GFR ratio is significantly associated with CI-AKI after pPCI.
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Celik O., Ozturk D., Akin F., Ayca B., Yalcin A. A. , Erturk M., Biyik I., Ayaz A., Akturk I. F. , Enhos A., et al., -Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention-, ANGIOLOGY, cilt.66, ss.519-524, 2015
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