Publication:
Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence

Loading...
Thumbnail Image
Date
2014-04-01
Authors
ÖZSÜTÇÜ, Mustafa
AYINTAP, Emre
Akkan, JÜLİDE CANAN
KOYTAK, Arif
ARAS, Cengiz
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue

Metrics

Search on Google Scholar

Abstract
Aims: To evaluate the efficacy of repeated bevacizumab injection in rotational conjunctival flap surgery versus rotational conjunctival flap with adjunctive mitomycin C (MMC) or rotational conjunctival flap alone. Materials and methods: Ninety eyes of 90 patients who underwent primary pterygium surgery with rotational flap were evaluated. Patients were randomly assigned to undergo conjunctival rotational flap alone (Group A) or conjunctival rotational flap with either 0.02% MMC application (Group B) or adjunctive subconjunctival 2.5 mg/0.1 ml bevacizumab injection (Group C). Each group consisted of 30 eyes. Recurrence rates at 9 months were evaluated. Results: There were no statistically significant differences in mean size of the pterygium across the limbus in terms of length (P > 0.5). The recurrence rates at 9 months were 26.6% (n = 8) in Group A, 13.3% (n = 4) in Group B, and 10% (n = 3) in Group C. The recurrence rates in Group B and C were significantly lower than in Group A (P = 0.1806). The recurrence rates were similar in Group B and C (P > 0.05). Conclusions: Subconjunctival bevacizumab injection may decrease the recurrence rate of primary pterygium surgery with rotational conjunctival flap. Further studies with a larger population and longer follow-up period are needed to supplement this study.
Description
Keywords
Citation
ÖZSÜTÇÜ M., AYINTAP E., Akkan J. C. , KOYTAK A., ARAS C., -Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence-, INDIAN JOURNAL OF OPHTHALMOLOGY, cilt.62, ss.407-411, 2014
Page Views

0

File Downloads

0

Sustainable Development Goals