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Sit-to-stand test in children with bronchiectasis: Does it measure functional exercise capacity?

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dc.contributor.authorZeren, Melih
dc.contributor.authorGürses, Hülya Nilgün
dc.contributor.authorDenizoğlu Külli, Hilal
dc.contributor.authorUçgun, Hikmet
dc.contributor.authorÇakır, Erkan
dc.contributor.institutionauthorGÜRSES, HÜLYA NILGÜN
dc.contributor.institutionauthorDENİZOĞLU KÜLLİ, HİLAL
dc.contributor.institutionauthorUÇGUN, HİKMET
dc.contributor.institutionauthorÇAKIR, ERKAN
dc.date.accessioned2020-10-01T20:59:07Z
dc.date.available2020-10-01T20:59:07Z
dc.date.issued2020-09-01T00:00:00Z
dc.description.abstractBackground Similar to six-minute walk test (6MWT), sit-to-stand test (STST) is a self-paced test which elicits sub-maximal effort; therefore, it is suggested as an alternative measurement for functional exercise capacity in various pulmonary conditions including COPD and cystic fibrosis. We aimed to investigate the association between 30-second STST (30s-STST) and 6MWT in both children with bronchiectasis (BE) and their healthy counterparts, as well as exploring cardiorespiratory burden and discriminative properties of both tests. Methods Sixty children (6 to 18-year-old) diagnosed with non-cystic fibrosis BE and 20 age-matched healthy controls were included. Both groups performed 30s-STST and 6MWT. Test results, and heart rate, SpO2 and dyspnea responses to tests were recorded. Results Univariate analysis revealed that 30s-STST was able to explain 52% of variance in 6MWT (r = 0.718, p<0.001) in BE group, whereas 20% of variance in healthy controls (r = 0.453, p = 0.045). 6MWT elicited higher changes in heart rate and dyspnea level compared to 30s-STST, indicating it was more physically demanding. Both 30s-STST (21.65±5.28 vs 26.55±3.56 repetitions) and 6MWT (538±85 vs 596±54 m) were significantly lower in BE group compared to healthy controls (p<0.01). Receiver operating characteristic (ROC) curve analysis revealed an area under the ROC curve (UAC) of 0.765 for 30s-STST and 0.693 for 6MWT in identifying the individuals with or without BE (p<0.05). Comparison between AUCs of 30s-STST and 6MWT yielded no significant difference (p = 0.466), indicating both tests had similar discriminative properties. Conclusions 30s-STST is found to be a valid alternative measurement for functional exercise capacity in children with BE.en
dc.identifier.citationZeren M., Gürses H. N. , Denizoğlu Külli H., Uçgun H., Çakır E., -Sit-to-stand test in children with bronchiectasis: Does it measure functional exercise capacity?-, Heart & Lung, cilt.6, no.49, ss.796-802, 2020
dc.identifier.doi10.1016/j.hrtlng.2020.09.017
dc.identifier.pubmed33010517
dc.identifier.urihttp://hdl.handle.net/20.500.12645/20157
dc.identifier.urihttps://doi.org/10.1016/j.hrtlng.2020.09.017
dc.subjectBronchiectasis
dc.subjectChildren
dc.subjectFunctional exercise capacity
dc.subjectValidity
dc.subjectSix-minute walk test
dc.subjectSit-to-stand test
dc.titleSit-to-stand test in children with bronchiectasis: Does it measure functional exercise capacity?
dc.typeArticle
dspace.entity.typePublication
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