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A case of cerebral phaeohyphomycosis caused by Fonsecaea monophora, a neurotropic dematiaceous fungus, and a review of the literature

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dc.contributor.authorDoymaz, Mehmet Z.
dc.contributor.authorGultepe, Bilge S.
dc.contributor.authorHakyemez, Ismail
dc.contributor.authorCEVIK, Serdar
dc.contributor.authorASLAN, Turan
dc.contributor.institutionauthorDOYMAZ, MEHMET ZIYA
dc.contributor.institutionauthorSEYİTHANOĞLU, MEHMET HAKAN
dc.contributor.institutionauthorHAKYEMEZ, İSMAİL NECATİ
dc.contributor.institutionauthorSÜMBÜL, BİLGE
dc.date.accessioned2019-10-05T14:30:18Z
dc.date.available2019-10-05T14:30:18Z
dc.date.issued2015-03-01
dc.description.abstractThe Fonsecaea species, which are the leading causes of chromoblastomycosis, are not considered neurotropic fungal agents. Fonsecaea pedrosoi is the primary species in the genus and is usually isolated from chromoblastomycosis cases. However, the recently distinguished species F. monophora has been reported in a few cerebral phaeohyphomycosis cases. Here, a case of cerebral phaeohyphomycosis caused by Fonsecaea monophora is presented in a 71-year-old female subject with chronic diabetes mellitus and hypertension. The identification of F. monophora was made through mycological and molecular analysis, and an isolate was differentiated from the closely related F.pedrosoi by sequence data on key bases on the ribosomal internal transcribed spacer region. The case was successfully treated with surgical and medical approaches, and the patient has remained healthy and stable after a ten-month follow up. Given the increasing incidence of this type of infection of the central nervous system (CNS), this case provides further support for the consideration that F. monophora might represent a neurotropic agent.
dc.identifier10.2174/1389557517666170425102827
dc.identifier.citationDoymaz M. Z. , Seyithanoglu M. F. , Hakyemez I., Gultepe B. S. , CEVIK S., ASLAN T., -A case of cerebral phaeohyphomycosis caused by Fonsecaea monophora, a neurotropic dematiaceous fungus, and a review of the literature-, MYCOSES, cilt.58, ss.187-192, 2015
dc.identifier.pubmed25591071
dc.identifier.urihttps://hdl.handle.net/20.500.12645/4068
dc.language.isoen
dc.titleA case of cerebral phaeohyphomycosis caused by Fonsecaea monophora, a neurotropic dematiaceous fungus, and a review of the literature
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameMini-Reviews in Medicinal Chemistry
local.avesis.id62e98e8e-e1a2-4401-98ec-9d79850786ba
local.avesis.response3938
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
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