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Comparison of ketamine-propofol and ketamine-dexmedetomidine combinations in children for sedation during tooth extraction

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dc.contributor.authorCanpolat, Dilek Gunay
dc.contributor.authorYildirim, Mustafa Denizhan
dc.contributor.authorKutuk, Nukhet
dc.contributor.authorDOĞRUEL, FATMA
dc.contributor.authorOcak, Hakan
dc.contributor.authorAKSU, RECEP
dc.contributor.authorAlkan, ALPER
dc.contributor.institutionauthorKÜTÜK, NÜKHET
dc.contributor.institutionauthorALKAN, ALPER
dc.date.accessioned2019-12-29T20:59:37Z
dc.date.available2019-12-29T20:59:37Z
dc.date.issued2017-05-01
dc.description.abstractObjective: To evaluate the efficiency of ketamine-propofol and ketamine-dexmedetomidine drugs in children for sedation during tooth extraction. Methods: The randomised, prospective study was conducted at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Erciyes University, Kayseri, Turkey, from September to November 2013, and comprised children who were due to undergo tooth extraction. Non-invasive blood pressures (systolic and diastolic), peripheral oxygen saturation, heart and respiratory rates and Ramsay Sedation Scores were assessed at baseline, after applying the drugs and then every 5 minutes thereafter. Further, the ketamine-propofol group received 1mg kg-1 of ketamine and propofol, and the ketamine-dexmedetomidine group received 1mg kg-1 of ketamine + 0.5 µg kg1 of dexmedetomidine. Results: Of the 60 participants, there were 30 (50%) in each group. No statistically significant differences were found in terms of heart rate, non-invasive blood pressures at any time and the number of drug repetitions (p>0.05). Nausea-vomiting was statistically higher in the ketamine-dexmedetomidine group (p<0.05). Conclusion: Ketamine-propofol might be a better option due to lower vomiting and nausea episodes and higher surgeon satisfaction levels.en
dc.identifier.citationCanpolat D. G. , Yildirim M. D. , Kutuk N., DOĞRUEL F., Ocak H., AKSU R., Alkan A., -Comparison of ketamine-propofol and ketamine-dexmedetomidine combinations in children for sedation during tooth extraction-, JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, cilt.67, ss.693-697, 2017
dc.identifier.pubmed28507353
dc.identifier.scopus85017247901
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/11110
dc.identifier.urihttps://jpma.org.pk/article-details/8187?article_id=8187
dc.identifier.wosWOS:000399243600008
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjectDexmedetomidine
dc.subjectKetamine
dc.subjectPropofol
dc.subjectTooth extraction
dc.titleComparison of ketamine-propofol and ketamine-dexmedetomidine combinations in children for sedation during tooth extraction
dc.typeArticle
dspace.entity.typePublication
local.avesis.idad84aace-f7e8-4212-bf7b-2ce80de3d885
local.publication.isinternational1
relation.isAuthorOfPublication908c31f8-027f-44c3-9992-1f8b42ac3367
relation.isAuthorOfPublicationf621b6f2-1415-4076-b3a2-78835a8712bd
relation.isAuthorOfPublication.latestForDiscoveryf621b6f2-1415-4076-b3a2-78835a8712bd
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