Publication:
Factors effective on peritoneal phosphorus transport and clearance in peritoneal dialysis patients

Simple item page
dc.contributor.authorCebeci, Egemen
dc.contributor.authorGursu, MELTEM
dc.contributor.authorUzun, Sami
dc.contributor.authorKaradağ, Serhat
dc.contributor.authorKazancioglu, RÜMEYZA
dc.contributor.authorÖztürk, Savas
dc.contributor.institutionauthorGÜRSU, MELTEM
dc.contributor.institutionauthorKAZANCIOĞLU, RÜMEYZA
dc.date.accessioned2019-10-05T13:03:56Z
dc.date.available2019-10-05T13:03:56Z
dc.date.issued2017-02-01
dc.description.abstractAims: Transport characteristics of phosphorus are different from other small solutes that are evaluated in routine peritoneal equilibration test ( PET) in peritoneal dialysis (PD) patients. We aimed to evaluate peritoneal phosphorus clearance and permeability, and their relationship with peritoneal membrane transport type and creatinine clearance as well as factors affecting peritoneal phosphorus clearance. Methods: 70 adult patients on a PD program were included in our study. Phosphorus transport status was classified according to dialysate/plasma (D/P) phosphorus at the 4th hour of PET as slow transporter ( 0.67). We evaluated the relationship of peritoneal phosphorus clearance and transport type with PD regime, phosphorus level, and presence of residual renal function in addition to investigating factors that are effective on peritoneal phosphorus clearance. Results: D/P phosphorus and peritoneal phosphorus clearance were positively correlated with D/ P creatinine and peritoneal creatinine clearance, respectively. Automated PD and continuous ambulatory PD patients were similar regarding phosphorus and creatinine clearances and transport status based on D/ P phosphorus. The major determinant of peritoneal phosphorus clearance was anuria status. Anuric patients had higher dialysate volume (11.6 +/- 3.0 L vs. 8.4 +/- 2.1 L, p < 0.001) and therefore higher peritoneal phosphorus clearance (61.7 +/- 15.1 L/week/1.73 m(2) vs. 48.4 +/- 14.0 L/week/1.73 m(2), p = 0.001). Hyperphosphatemia was present in 40% and 11% of anuric patients and those with residual renal function, respectively (p = 0.005). Conclusions: Peritoneal phosphorus transport characteristics are similar to that of creatinine. Although increased dialysis dose may increase peritoneal phosphorus clearance, it may be insufficient to prevent hyperphosphatemia in anuric patients.
dc.identifier10.1097/00006982-200510000-00007
dc.identifier.citationCebeci E., Gursu M., Uzun S., Karadağ S., Kazancioglu R., Öztürk S., -Factors effective on peritoneal phosphorus transport and clearance in peritoneal dialysis patients-, CLINICAL NEPHROLOGY, cilt.87, ss.76-83, 2017
dc.identifier.doi10.5414/cn108954
dc.identifier.scopus85012289399
dc.identifier.urihttps://hdl.handle.net/20.500.12645/1212
dc.identifier.wosWOS:000397033600003
dc.titleFactors effective on peritoneal phosphorus transport and clearance in peritoneal dialysis patients
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameRETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
local.avesis.id1c57a0ef-0747-40a0-85c5-c59f94694096
local.avesis.response1082
local.org.facultyTıp Fakültesi
local.publication.isinternational1
relation.isAuthorOfPublicationa6446eac-0ccd-4457-9227-3fc72dec68d1
relation.isAuthorOfPublicationeca7bd30-6b6e-444d-96ae-2961c39f2107
relation.isAuthorOfPublication.latestForDiscoverya6446eac-0ccd-4457-9227-3fc72dec68d1
Files
Collections
Yayınlar - Eserler