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Anticholinergic and antioxidant activities of avocado (Folium perseae) leaves - phytochemical content by LC-MS/MS analysis

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dc.contributor.authorKose, Leyla Polat
dc.contributor.authorBingol, Zeynebe
dc.contributor.authorKaya, Ruya
dc.contributor.authorGÖREN, AHMET CEYHAN
dc.contributor.authorAkincioglu, Hulya
dc.contributor.authorDURMAZ, LOKMAN
dc.contributor.authorKÖKSAL, EKREM
dc.contributor.authorAlwasel, Saleh H.
dc.contributor.authorGÜLÇİN, İlhami
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2020-08-19T20:59:10Z
dc.date.available2020-08-19T20:59:10Z
dc.date.issued2020-01-01T00:00:00Z
dc.description.abstractIn the first stage of the manuscript, we aimed to examine antioxidant capacity and anticholinergic properties of avocado (Folium perseae) leaves. Avocado leaf was extracted by water (WEFP) and ethyl alcohol (EEFP) and antioxidant activity was determined using by several antioxidant assays including DPPHGreek ano teleia and ABTS(center dot+)radical scavenging assays, Cu2+-Cu(+)reducing, Fe3+-Fe(2+)reducing, and FRAP reducing activities. Avocado leaf extracts demonstrated antioxidant activity and anticholinergic activities, while alpha-tocopherol, BHT, trolox, and BHA were used as positive antioxidant controls. In the second part of this study, the inhibition effects of WEFP and EEFP were valuated against acetylcholinesterase and butyrylcholinesterase enzymes, which catalyze the breakdown of choline esters (i.e. neurotransmitters). This study obviously showed that avocado leaf extracts had effective antioxidant, antiradical, and anticholinergic influences.
dc.identifier.citationKose L. P. , Bingol Z., Kaya R., GÖREN A. C. , Akincioglu H., DURMAZ L., KÖKSAL E., Alwasel S. H. , GÜLÇİN İ., -Anticholinergic and antioxidant activities of avocado (Folium perseae) leaves - phytochemical content by LC-MS/MS analysis-, INTERNATIONAL JOURNAL OF FOOD PROPERTIES, cilt.23, ss.878-893, 2020
dc.identifier.doi10.1080/10942912.2020.1761829
dc.identifier.scopus85087380763
dc.identifier.urihttp://hdl.handle.net/20.500.12645/18408
dc.identifier.wosWOS:000544479400001
dc.language.isoen
dc.titleAnticholinergic and antioxidant activities of avocado (Folium perseae) leaves - phytochemical content by LC-MS/MS analysis
dc.typeArticle
dspace.entity.typePublication
local.avesis.id619b4125-c466-4b1a-a4a8-5eaf3a441ea5
local.publication.isinternational1
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
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