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Analysis of Appendiceal Neoplasms on 3544 Appendectomy Specimens for Acute Appendicitis: Retrospective Cohort Study of a Single Institution

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dc.contributor.authorDestek, Sebahattin
dc.contributor.authorBektasoglu, HÜSEYİN KAZIM
dc.contributor.authorUnver, NURCAN
dc.contributor.authorAydogan, CEYHUN
dc.contributor.authorTimocin, GİZEM
dc.contributor.institutionauthorKUNDUZ, ENVER
dc.contributor.institutionauthorBEKTAŞOĞLU, HÜSEYİN KAZIM
dc.contributor.institutionauthorÜNVER, NURCAN
dc.contributor.institutionauthorAYDOĞAN, CEYHUN
dc.contributor.institutionauthorTİMOÇİN, GİZEM
dc.contributor.institutionauthorDESTEK, SABAHATTİN
dc.date.accessioned2019-10-05T21:56:48Z
dc.date.available2019-10-05T21:56:48Z
dc.date.issued2018-06-27
dc.description.abstractBACKGROUND Appendiceal neoplasms are rare and generally determined in appendectomy specimens for acute appendicitis. Depending on a tumor's histopathology and size, appendectomy or right hemicolectomy are the surgical treatment options. Adenocarcinomas, mucinous neoplasms, goblet cell carcinoids and neuroendocrine tumors are the types of the primary appendiceal neoplasm histopathology. In this study, we aimed to determine the incidence of appendiceal neoplasms in an acute appendicitis cohort. Also, histopathological distributions, demographic data, preoperative radiological diagnosis, and intraoperative findings were revealed for analysis, retrospectively. MATERIAL AND METHODS Between October 2011 and September 2017, 3554 appendectomies were performed for acute appendicitis in Bezmialem University Hospital, Istanbul Turkey. The medical records of these consecutive 3554 patients were evaluated retrospectively. After the histopathological analysis of the appendectomy specimens, a total of 28 patients were detected as having appendiceal neoplasm including appendiceal adenocarcinoma, low grade mucinous neoplasia, and appendiceal neuroendocrine tumors. RESULTS Appendiceal neoplasms were determined in 28 out of 3554 acute appendicitis patients with an incidence of 0.78%. According to the histopathological types, 3 of the cases (10.7%) were appendiceal adenocarcinoma, 8 of the cases (28.5%) were low grade mucinous neoplasia, and 17 of the cases (60.8%) were neuroendocrine tumors. The overall incidence of the appendiceal neuroendocrine tumors was 0.48%. CONCLUSIONS The information obtained from our study suggests that pathological examination of the specimen may not be necessary if there is no doubt according to preoperative radiological diagnosis and/or intraoperative findings of the surgeon.en
dc.identifier10.4274/tpa.46.03
dc.identifier.citationKunduz E., Bektasoglu H. K. , Unver N., Aydogan C., Timocin G., Destek S., -Analysis of Appendiceal Neoplasms on 3544 Appendectomy Specimens for Acute Appendicitis: Retrospective Cohort Study of a Single Institution-, MEDICAL SCIENCE MONITOR, cilt.24, ss.4421-4426, 2018
dc.identifier.pubmed29947345
dc.identifier.urihttps://hdl.handle.net/20.500.12645/8518
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleAnalysis of Appendiceal Neoplasms on 3544 Appendectomy Specimens for Acute Appendicitis: Retrospective Cohort Study of a Single Institution
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameTURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
local.avesis.idd45a15cc-4a9d-4e1d-82fc-d7e7c9f31ec7
local.avesis.response8394
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relation.isAuthorOfPublication884711f3-71a4-47dd-88e7-486287ed148d
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relation.isAuthorOfPublication.latestForDiscovery974d991e-4961-4ee5-b07d-733ed7ce5dbf
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