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Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence

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dc.contributor.authorÖZSÜTÇÜ, Mustafa
dc.contributor.authorAYINTAP, Emre
dc.contributor.authorAkkan, JÜLİDE CANAN
dc.contributor.authorKOYTAK, Arif
dc.contributor.authorARAS, Cengiz
dc.contributor.institutionauthorUMURHAN AKKAN, JÜLİDE CANAN
dc.contributor.institutionauthorKOYTAK, İBRAHİM ARİF
dc.date.accessioned2019-10-05T23:20:36Z
dc.date.available2019-10-05T23:20:36Z
dc.date.issued2014-04-01
dc.description.abstractAims: To evaluate the efficacy of repeated bevacizumab injection in rotational conjunctival flap surgery versus rotational conjunctival flap with adjunctive mitomycin C (MMC) or rotational conjunctival flap alone. Materials and methods: Ninety eyes of 90 patients who underwent primary pterygium surgery with rotational flap were evaluated. Patients were randomly assigned to undergo conjunctival rotational flap alone (Group A) or conjunctival rotational flap with either 0.02% MMC application (Group B) or adjunctive subconjunctival 2.5 mg/0.1 ml bevacizumab injection (Group C). Each group consisted of 30 eyes. Recurrence rates at 9 months were evaluated. Results: There were no statistically significant differences in mean size of the pterygium across the limbus in terms of length (P > 0.5). The recurrence rates at 9 months were 26.6% (n = 8) in Group A, 13.3% (n = 4) in Group B, and 10% (n = 3) in Group C. The recurrence rates in Group B and C were significantly lower than in Group A (P = 0.1806). The recurrence rates were similar in Group B and C (P > 0.05). Conclusions: Subconjunctival bevacizumab injection may decrease the recurrence rate of primary pterygium surgery with rotational conjunctival flap. Further studies with a larger population and longer follow-up period are needed to supplement this study.en
dc.identifier10.1016/j.mri.2004.11.003
dc.identifier.citationÖZSÜTÇÜ M., AYINTAP E., Akkan J. C. , KOYTAK A., ARAS C., -Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence-, INDIAN JOURNAL OF OPHTHALMOLOGY, cilt.62, ss.407-411, 2014
dc.identifier.pubmed24178405
dc.identifier.urihttps://hdl.handle.net/20.500.12645/10054
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleRepeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameMAGNETIC RESONANCE IMAGING
local.avesis.idfadab0b7-23f3-40e0-acb0-9ea8dc350035
local.avesis.response9928
relation.isAuthorOfPublication0ac69bf6-a1a3-4a8b-be3a-ee84839bbc03
relation.isAuthorOfPublicationad20e4da-e310-4188-9b32-8fb51734eb5f
relation.isAuthorOfPublication.latestForDiscovery0ac69bf6-a1a3-4a8b-be3a-ee84839bbc03
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