Publication:
Bilateral carotid paraganglioma: surgery and radiotherapy.

dc.contributor.authorKiziltan, HURİYE ŞENAY
dc.contributor.authorOZUCER, B
dc.contributor.authorERIS, ALİ HİKMET
dc.contributor.authorVEYSELLER, B
dc.contributor.institutionauthorKIZILTAN, HURİYE ŞENAY
dc.contributor.institutionauthorERİŞ, ALİ HİKMET
dc.date.accessioned2019-10-05T21:24:51Z
dc.date.available2019-10-05T21:24:51Z
dc.date.issued2014-07-03
dc.description.abstractBackground: Paragangliomas are relatively rare vascular tumors that develop from the neural crest cells of carotid bifurcation. They usually present as slow-growing, painless unilateral neck masses; bilateral presentation is rare and is mostly associated with familial forms. Bilateral total resection is not always possible for high-grade bilateral tumors, and radiotherapy is a good alternative, with cure rates similar to surgery. Case report: A 35-year-old female patient was admitted with a chief complaint of a bilateral, painless mass located on her neck. Subsequent magnetic resonance imaging (MRI) and angiographic imaging revealed bilateral hypervascular masses surrounding her carotid at 360°, and they were interpreted as stage 3 carotid paragangliomas according to the Shamblin classification protocol. Surgery was carried out on the left carotid paraganglioma and the mass was totally resected. It was thought that the patient could not tolerate bilateral surgery. Primary radiotherapy was planned on the right carotid paraganglioma: 59.8 gray (Gy) conformal, Linac-based multileaf collimator radiotherapy with a 180 cGy daily dosage, and five fractions per week were planned. Results: Follow-up at 3 months following the conclusion of radiotherapy revealed no significant regression. A follow-up MRI 6 months and 24 months later revealed 59% regression. Grade 2 esophagitis and minimal neck edema were the only complications noted during the course of radiotherapy and during the 24-month follow-up period. No complications or relapse were observed except for edema following neck surgery.en
dc.identifier10.1016/0160-5402(90)90034-i
dc.identifier.citationKiziltan H. Ş. , OZUCER B., ERIS A. H. , VEYSELLER B., -Bilateral carotid paraganglioma: surgery and radiotherapy.-, Clinical medicine insights. Case reports, cilt.7, ss.53-7, 2014
dc.identifier.pubmed25057243
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/7241
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleBilateral carotid paraganglioma: surgery and radiotherapy.
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameJOURNAL OF PHARMACOLOGICAL METHODS
local.avesis.idb472826d-48ec-4a96-b163-0388a7cfc919
local.avesis.response7117
relation.isAuthorOfPublication91868cfc-cd33-4b57-98b2-792bfc24eedb
relation.isAuthorOfPublicationb64c5e89-2a6e-4d0f-bdab-ff902eba9f0a
relation.isAuthorOfPublication.latestForDiscovery91868cfc-cd33-4b57-98b2-792bfc24eedb
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