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The relationship of neutrophil to lymphocyte ratio with testicular cancer

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dc.contributor.authorİlktaç, Abdullah
dc.contributor.authorAkbulut, Habib
dc.contributor.authorAkçay, Muzaffer
dc.contributor.authorErsöz, Cevper
dc.contributor.authorDoğan, Bayram
dc.contributor.institutionauthorİLKTAÇ, ABDULLAH
dc.contributor.institutionauthorDOĞAN, BAYRAM
dc.contributor.institutionauthorERSÖZ, CEVPER
dc.contributor.institutionauthorAKÇAY, MUZAFFER
dc.contributor.institutionauthorAKBULUT, HABİB
dc.date.accessioned2019-12-23T20:59:16Z
dc.date.available2019-12-23T20:59:16Z
dc.date.issued2020-01-01
dc.description.abstractPurpose: To assess the relationship between testicular germ cell tumors (TGCT) and neutrophil to lymphocyte ratio (NLR) and to determine whether this ratio can be used as a serum tumor marker. Material and Methods: Sixty-one patients with testicular germ cell tumors were included into the study. Patients were grouped as localized and non-localized. Histologically patients were categorized as seminoma and nonseminomatous germ cell tumors. Complete blood cell count was measured the day before surgery and at the postoperative 1st month. Preoperative and postoperative mean NLR values were compared. Results: Thirty-six patients (59%) had seminomas and 25 patients (41%) had nonseminomatous testicular cancer. Forty-fi ve patients (73.8%) had localized and 16 patients (26.2%) had non-localized testicular cancer. There was a statistically signifi cant difference between preoperative and postoperative mean NLR of the localized patients (p=0.001) but no such difference was detected for non-localized patients (p=0.576). Nineteen patients with localized seminomas had normal preoperative serum tumor markers. There was a signifi cant difference between preoperative and postoperative mean NLR in this group of patients (p=0.010). Twenty-six patients with localized tumors had preoperative increased serum tumor markers which normalized after orchiectomy. Mean NLR of these patients signifi cantly decreased from 3.10±2.13 to 1.62±0.59 postoperatively (p=0.010). Conclusions: NLR appears to be a useful marker for TGCT. It is successful in predicting localized and non-localized disease in early postoperative period.en
dc.identifier.citationİlktaç A., Doğan B., Ersöz C., Akçay M., Akbulut H., -The relationship of neutrophil to lymphocyte ratio with testicular cancer-, International Braz J Urol, cilt.46, ss.101-107, 2020
dc.identifier.pubmed31851466
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/10729
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968911/
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjectBiomarkers
dc.subjectOrchiectomy
dc.subjectTesticular Neoplasms
dc.titleThe relationship of neutrophil to lymphocyte ratio with testicular cancer
dc.typeArticle
dspace.entity.typePublication
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local.publication.goal03 - Sağlık ve Kaliteli Yaşam
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