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GÜLER, BERIL

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BERIL
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GÜLER
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Start date: 2015 × End date: 2019 ×

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Now showing 1 - 10 of 17
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    Effect of a combination in situ gel-forming nasal delivery system on nasal mucosa damage repair in rabbits
    (2017-10-17) AKSOY, FADLULLAH; DOĞAN, REMZİ; OZTURAN, ORHAN; ALTUNTAŞ, EBRU; YENER, FATMA GÜLGÜN; TOPÇU, GÜLAÇTI; GÜLER, BERİL; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; TOPÇU, GÜLAÇTI; GÜLER, BERIL
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    A rare entity: Bone marrow metastasis in a patient with Wilms tumor
    (2016-10-01T00:00:00Z) Kaygusuz, Sare Betül; Çakır, Fatma Betül; Göç, Rümeysa; Güler, Beril; Gücin, Zühal; ÇAKIR, FATMA BETÜL; GÜLER, BERIL; GÜCİN, ZÜHAL
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    PublicationOpen Access
    Vulvar granular cell tumor
    (2016-07-01) Sonmez, FATMA CAVİDE; KOROGLU, Nadiye; Guler, BERİL; Arici, DİLEK SEMA; SÖNMEZ, FATMA CAVİDE; GÜLER, BERIL; ARICI, DILEK SEMA
    Granular cell tumors (GCTs) are rare and approximately half of the all lesions arise from head and neck, especially from the tongue. However, they are rarely seen in the vulva. They can occur in patients of any age, but peak age incidence is in the fourth to sixth decades. They generally occur as small, slow growing, and skin-colored nodule. GCTs are usually benign, but malignant cases were reported. Recurrence can be seen in benign tumors with clear margins, but rates increase with positive margins. The treatment is complete surgical excision. We report a case of benign GCT of the vulva. A 41-year-old patient presented with vulvar mass, and biopsy was consisted with GCT.
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    2017 YILI TİROİD KOR BİYOPSİ ve REZEKSİYON MATERYALLERİNDE PATOLOJİK KORELASYON. 1336 OLGULUK DENEYİMİMİZ.
    (2019-03-16T00:00:00Z) Güler, Beril; GÜLER, BERIL
    Giriş: Nodüler tiroid lezyonlarının takibinde altın standart, tiroid ince iğne aspirasyon sitolojisidir. Bununla birlikte güncel literatürlerin bir kısmında, özellikle mükerrer yetersiz tanısı alan olgular ile kalsifiye nodüllerde alternatif yöntem olarak kor biopsi örneklemesi önerilmektedir. Nadir olarak bazı merkezlerde ise ince iğne aspirasyon sitolojisi yerine tercih edilmektedir.Materyal-Metod: Bu çalışmada, 2017 yılı içinde bölümümüze gönderilen tiroid kor biopsilerinin retrospektif olarak, patolojik tanısal dağılımının belirlenmesi amaçlanmaktadır. Tiroid için rutinde uygulanan bir örnekleme yöntemi olmadığından patolojik tanı gruplaması için net kabul görmüş bir sınıflama henüz bulunmamaktadır. Tanısal gruplar oluşturulurken, Bethesda sistemine benzer bir sınıflama uyarlanmaya çalışılmıştır.Bulgular: Bir yıl içinde bölümümüzde değerlendirilen tiroid kor biopsi toplam sayısı 1336’dır. Olguların 1077’si benign, 29’u malign, 50’si malignite şüphesi, 44’ü önemi belirsiz atipi/önemi belirsiz foliküler lezyon (AUS/FLUS), 30’u foliküler neoplazi şüphesi tanı katergorilerine dahil edilmiştir. 104 olgu tanısal gruplama için yetersiz kabul edilmiştir. Bir olguda paratiroid dokusu izlenmiştir. Rezeke edilen 25 malign tanılı olgunun tümü rezeksiyon tanılarıyla koreledir. Malignite şüphesi tanısı almış 35 olgunun ise 33’ünde papiller karsinom, 1’inde medüller karsinom saptanmış, 1 olgu ise benign olarak sonuçlanmıştır. AUS/FLUS tanılı olguların 17’si rezeke edilmiş, 9’u benign, 8’i malign tanısı almıştır.Tartışma: Bölümümüzde değerlendirilen tiroid vakalarında kor biopsi yöntemi aspirasyon sitoloji örneklerinin yaklaşık 3 katı kadardır. Sınırlı sayıda merkezde uygulanan bu yöntemin, rezeksiyonları ile korele edilerek sunulan, patolojik tanı gruplarını sizlerle paylaşmak istedik.Anahtar Kelimeler: tiroid, kor biyopsi, tiroidektomi
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    A Rare Entity: Bone Marrow Metastasis in a Patient with Wilms Tumour
    (2016-10-19) Kaygusuz S. B.; Çoban G.; Güler B.; Çakır F. B.; Gücin Z.; ÇOBAN, GANİME; GÜLER, BERIL; ÇAKIR, FATMA BETÜL
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    PublicationOpen Access
    The diagnostic ability of core needle biopsy in nodular thyroid disease.
    (2017-03-01) Aysan, E; KIRAN, TUĞÇE; IDIZ, UO; AKBULUT, H; GULER, B; KUNDUZ, ENVER; ARICI, S; KADAKAL, G; Ozgor, M; Coci, K; AYŞAN, MUSTAFA ERHAN; KIRAN, TUĞÇE; GÜLER, BERIL; KUNDUZ, ENVER
    INTRODUCTION Non-diagnostic results of fine needle aspiration biopsy (FNAB) remain an important limitation of this technqiue. The aim of our study was to evaluate the results of core needle biopsy (CNB) of thyroid nodules and its effectiveness in non-diagnostic FNAB cases. METHODS CNBs were performed in 1,000 patients (154 male, 846 female; mean age: 50.2 years, range: 18–86 years) with a spring loaded 20G needle. Of these, 143 had initially had FNABs that were insufficient for evaluation. The CNB reports were reviewed. Patients with suspicious or malignant CNB results underwent total thyroidectomy. RESULTS When considering all 1,000 CNBs, the non-diagnostic rate was 1.5% (15/1,000). However, when the first 100 cases were eliminated as a learning curve, this reduced to 0.9% (8/900). Of the 143 cases with initial FNABs that were non-diagnostic, 0.7% (1/143) were also non-diagnostic on CNB. Twelve patients underwent surgery because of malignant CNB reports and all of these cases were confirmed as malignant by the postoperative pathology specimen results (100% accuracy). There were no major complications although three self-limiting minor complications were observed. CONCLUSIONS CNB is a safe and accurate method. It is more diagnostic than FNAB for nodular thyroid disease.
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    Effect of a combination of mometasone furoate, levofloxacin, and retinyl palmitate with an in situ gel-forming nasal delivery system on nasal mucosa damage repair in an experimental rabbit model
    (2017-12-01) AKSOY, Fadlullah; DOĞAN, REMZİ; ÖZTURAN, ORHAN; ALTUNTAŞ, Ebru; YENER, FATMA GÜLGÜN; TOPÇU, GÜLAÇTI; GÜLER, BERİL; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; TOPÇU, GÜLAÇTI; GÜLER, BERIL
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    Correlation Between Simultaneous Ultrasound-Guided Fine Needle Aspiration and Core Needle Biopsy Results in Thyroid Nodules of 44 Cases
    (2017-01-01T00:00:00Z) KIRAN, TUĞÇE; GÜLER, BERİL; AYŞAN, MUSTAFA ERHAN; ARICI, DİLEK SEMA; KIRAN, TUĞÇE; GÜLER, BERIL
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    Using a corkscrew-tipped telescopic nail in the treatment of osteogenesis imperfecta: a biomechanical study and preliminary results of 17 consecutive cases
    (2019-03-01T00:00:00Z) Sarikaya, Ilker; Seker, Ali; Erdal, Ozan Ali; GÜNAY, HÜSEYİN; Inan, Muharrem; GÜLER, BERİL; GÜLER, BERIL
    High complication rates were reported with the telescopic nail technique systems. To overcome such technical difficulties, we designed a corkscrew-tipped telescopic nail (CTTN). We biomechanically compared its pullout strength with that of two other tip designs. We used CTTN in 17 patients with osteogenesis imperfecta and reported their preliminary results. Average patient age was 82.6 months, and mean follow-up was 32.0 +/- 6 months. Telescoping and osteotomy site healing were assessed using radiological studies. Successful telescoping with event-free osteotomy site healing was achieved in 94.1% of patients; limited telescoping and delayed union were detected in one case each. Our results show that CTTN provides sufficient pullout strength and reduced complication rates compared with other designs. Copyright (C) 2018 Wolters Kluwer Health, Inc. All rights reserved.
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    Should Core Needle Biopsy be Used in the Evaluation of Thyroid Nodules?
    (2016-12-01) Guler, BERİL; Kiran, TUĞÇE; Arici, DİLEK SEMA; Aysan, Erhan; Sonmez, FATMA CAVİDE; GÜLER, BERIL; KIRAN, TUĞÇE; ARICI, DILEK SEMA; AYŞAN, MUSTAFA ERHAN; SÖNMEZ, FATMA CAVİDE
    Fine needle aspiration (FNA) is the first choice in thyroid nodules suspected of harboring malignancy on sonography in routine practice. However, sampling with core needle biopsy (CNB) is also being used, especially in cases with repeated nondiagnostic/indeterminate diagnoses. The aim of this study was the retrospective evaluation of CNB samples. A total of 604 thyroid CNB samples registered in the Department of Pathology at Bezmialem Foundation University Medical Faculty within the 1-year period between June 2014 and June 2015 were re-evaluated by correlation with previous FNA and later resection results. CNB was divided into diagnostic groups of insufficient, malignant, suspicious for malignancy, no evidence of malignancy/benign, atypia of uncertain significance (AUS)/follicular lesions of uncertain significance (FLUS), and follicular neoplasm (FN)/suspicious for follicular neoplasm (SFN). Among the 604 cases, 15 cases (2.48 %) were classified as malignant and 9 cases (1.49 %) as suspicious for malignancy. No evidence of malignancy was seen in 512 cases (84.76 %). There were 26 (4.3 %) cases in the AUS/FLUS-FN/SFN group, and the sample was inadequate in 42 cases (6.95 %). Resection was performed for 17 of the cases classified as malignant or suspicious for malignancy, and all were found to be malignant. There were also 10 resected cases with a diagnosis of no evidence of malignancy, and all were found to be benign. We think that sampling with CNB may be useful especially in repeating inadequate biopsies or cases diagnosed with AUS/FLUS that have hesitations regarding clinical management. Larger series including comparisons with FNA and resection results are required.