Person: YAPALAK, YUNUS
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Publication Metadata only Videoendoscopic pilonidal sinus surgery: early results with a new technique(2017-12-01) Kunduz, ENVER; Idiz, Ufuk Oguz; Aysan, Erhan; Güzel, MEHMET; Yapalak, YUNUS; Başköy, LÜTFULLAH; KUNDUZ, ENVER; GÜZEL, MEHMET; YAPALAK, YUNUS; BAŞKÖY, LÜTFULLAHWe adapted a laparoscopic surgical technique to sacrococcygeal pilonidal sinus disease (SPSD) treatment.Publication Metadata only Hemodynamic Instability during Thyroidectomy in Graves- Disease(2021-04-01T00:00:00Z) Acar, Sami; Ercetin, Candas; Sahbaz, Nuri Alper; Tutal, Firat; YAPALAK, YUNUS; Cosan, Fulya; Erbil, Yesim; YAPALAK, YUNUSBackground The aim of this study was to investigate the changes in vital signs and hemodynamic status that occur in patients during the intraoperative course of thyroidectomy in Graves- Disease (GD). Methods A total of 71 patients were included in the study. Patients were directed to surgery when they had large goiters with compressive symptoms or suspicious nodules, were pregnant or lactating, were unresponsive or intolerant to antithyroid drugs (ATDs), or expressed a preference to have surgery. All patients scheduled for operations underwent surgery while in the euthyroid state. Results Hemodynamic instability was observed in 18 patients during thyroidectomy. Disease duration, sample weight, and thyroid-stimulating hormone receptor antibodies (TRAb) levels were found to be effective on hemodynamic instability. Logistic regression analysis revealed an 11-fold increase in the instability risk in patients with a period of disease shorter than 21 months (P = 0.037). A TRAb value >11.5 increased the risk by 235fold (p < 0.001). Conclusion High levels of TRAb values and new onset of disease with shorter periods of ATDs use may be risk factors for hemodynamic instability during thyroidectomy. Patients with larger thyroid glands are at greater risk for instability during surgery. Those risks should be taken into account during surgery, and the surgical and anesthetic management of the patient should be made more carefully in concordance with the anesthesia team.Publication Metadata only AKUT APANDİSİT TANISINDA PENTRAXİN-3 VE DİĞER AKUT FAZ REAKTANLARININ DEĞERLENDİRİLMESİ(2019-10-29T00:00:00Z) Destek, Sabahattin; Yapalak, Yunus; DESTEK, SABAHATTİN; YAPALAK, YUNUSAMAÇ: Akut apandisit acil cerrahide en sık karşılaşılan akut batın tablosudur ve apandektomi acil cerrahi girişimleri arasında en fazla yapılan ameliyattır. Ancak geç tanı ve perforasyon oranı yüksekliği hala sorun olmayı sürdürmektedir. Bu sebeple akut apandisit tanısını koymaya ve desteklemeye yönelik testler geliştirilmeye devam etmektedir. Bu çalışmamızda serum lökosit, C-reaktif protein (CRP), prokalsitonin, fibrinojen ve pentraxin-3 düzeylerinin akut apandisitteki tanısal ve prognostik etkinliği araştırıldı. MATERYAL-METOD: Yetişkin hastalardan (18-84 yaş arası) oluşan kontrol (n=110) ve akut apandisit hasta grubu (n=77) oluşturuldu. Kontrol grubunda %69’u kadın, hasta grubunda %46.8’i kadındı. Hastaların demografik özellikleri, ameliyat öncesi serum lökosit, CRP, prokalsitonin, fibrinojen ve pentraxin-3 seviyeleri ile bunların ameliyat öncesi yapılan batın tomografisi (BT) skorlarıyla, Alvarado skorlarıyla, apandisitin histopatolojik evreleriyle olan ilişkisine bakıldı. BULGULAR: Ortalama yaş, hasta grubunda 36.1 ± 13.6, kontrol grubunda 47.7 ± 16.6 yıldı. BT’de hastaların %13’ünde (n=10) perfore apandisit saptandı. İstatiksel olarak BT skorlarıyla CRP (p=0.001), prokalsitonin (p=0.019), fibrinojen (p=0.025) arasında anlamlı korelasyon varken lökosit ve pentraksin-3 ile korelasyon saptanmadı. Alvarado skorları ile lökosit (p=0.001) ve prolaksitonin (p=0.037) arasında arasında anlamlı korelasyon saptanmışken; CRP, fibrinojen ve pentraksin-3 ile korelasyon bulunmadı. Histopatolojik incelemelerde hastaların %6.5’inde (n=5) perfore apandisit saptandı. Apendisitin histopatolojik evreleriyle CRP (p=0.0001), prokalsitonin (p=0.0001) ve fibrinojen (p=0.008) arasında anlamlı şekilde korelasyon varken lökosit ve pentraksin- 3 ile korelasyon saptanmadı. SONUÇ: Bu klinik çalışmamızda özellikle prokalsitonin düzeyleri akut apandisit tanısı ve hastalığın evresi ile ilgili olarak iyi bir gösterge olduğu bulundu. Diğer taraftan pentraksin-3’ün tanıda ve prognozun belirlenmesinde bir öneminin olmadığı belirlendi.Anahtar Kelimeler: Apandisit, akut faz reaktanı, pentraxin-3Publication Metadata only Clinical Significance of Erythrocyte Sedimentation Rate, Leukocyte, Fibrinogen, C-Reactive Protein, and Pentraxin 3 Values in Thyroid Nodules(2022-01-01T00:00:00Z) Destek, Sabahattin; Benturk, Beyza; Yapalak, Yunus; ÖZER, Ömer Faruk; DESTEK, SABAHATTİN; YAPALAK, YUNUS; ÖZER, ÖMER FARUKObjectives: Thyroid nodules (TN) are common. Genetic and environmental factors as well as chronic inflammation play a role in occurrence of these nodules. The key point in diagnostic assessment is to rule out malignancy. Biomarkers that can show the possibility of malignancy continue to be investigated. We evaluated the relationship between sedimentation rate, leukocyte, fibrinogen, C-reactive protein (CRP), and pentraxin 3 (PTX3) inflammatory markers and characteristics and cytology of TN. Methods: This study included a nodular goiter group with 55 persons and control group with 58 persons. Participants' gender, age, family history, thyroid function tests, sedimentation, leukocyte, fibrinogen, CRP, and PTX3 serum levels were recorded. The number of nodules, the largest nodule diameter, nodular echogenicity, and nodule structures were examined on ultrasonography (US) and thyroid biopsy was performed. Results: The number of TN in patients was between 1 and 4. The number of patients with two TN was higher (47.3%, n=26). Nodule diameters differed between 3 and 62 (mean 21) mm. In thyroid biopsy, papillary thyroid cancer was detected in 25.5% (n=14) of the patients. The number of nodules on US increased as CRP values increased (p=0.013). In addition, the number of nodules on US decreased as fibrinogen values increased (p=0.003). No significant difference was found between the groups in terms of sedimentation, leukocyte, and PTX3 values. Conclusion: The number of TN was positively correlated with CRP and negatively correlated with fibrinogen levels. However, there was no difference between benign and malignant differentiation and biomarkers. CRP values that correlate with the increase in the number of nodules can be used in prognosis and clinical follow-up.Publication Metadata only The Effects of the Staple Line Reinforcement Procedures on Gastrointestinal Symptoms and Its Early Results in Sleeve Gastrectomy(2022-08-01T00:00:00Z) YAPALAK, YUNUS; YIĞMAN, SAMET; GÖNÜLTAŞ, CEREN; COŞKUN, Halil; YARDIMCI, ERKAN; YAPALAK, YUNUS; YIĞMAN, SAMET; GÖNÜLTAŞ, CEREN; COŞKUN, HALIL; YARDIMCI, ERKANBackground: The laparoscopic sleeve gastrectomy (LSG) procedure is the most common bariatric surgical technique worldwide, but controversy continues over staple line reinforcement (SLR) techniques. This prospective randomized study aimed to compare the effects of SLR methods on early postoperative complications and gastrointestinal symptoms in patients undergoing LSG for morbid obesity.Publication Metadata only DOES HELICOBACTER PYLORI POSITIVITY AFFECT THE OUTCOMES OF LAPAROSCOPIC SLEEVE GASTRECTOMY? Sleeve gastrectomy(2017-07-01T00:00:00Z) BEKTAŞOĞLU, Hüseyin Kazım; YAPALAK, YUNUS; Bozkurt, S.; BEKTAŞOĞLU, HÜSEYİN KAZIM; YAPALAK, YUNUS; BOZKURT, SÜLEYMANPublication Open Access Comparison Of Surgical Technique And Results For Emergency Or Elective Femoral Hernia Repair(2019-01-01) KUNDUZ, ENVER; SORMAZ, ISMAIL; YAPALAK, YUNUS; Bektaşoğlu, HÜSEYİN KAZIM; GÖK, ALİ FUAT KAAN; KUNDUZ, ENVER; YAPALAK, YUNUS; BEKTAŞOĞLU, HÜSEYİN KAZIMBACKGROUND: Inguinal hernia affects 3–8% of the population. Femoral hernias are only a small number of groin hernias; however, femoral hernias are very important because these operations are generally emergency procedures, and bowel resections are frequently necessary. This study aims to compare surgical outcomes of patients with femoral hernias using different techniques under emergency or elective conditions. METHODS: Between April 2013 and November 2017, 52 patients with femoral hernias were admitted to the emergency department of the General Surgery Clinics at two university hospitals in Istanbul. The medical files of all the patients who underwent surgery with a diagnosis of a femoral hernia were retrospectively evaluated. The demographic data, hernia side information, sac contents, surgical technique, length of hospital stay, recurrence according to the last outpatient clinic and complications were retrospectively analyzed. RESULTS: The sex distribution of the cases was as follows: 88.5% (n=46) of the patients were female, and 11.5% (n=6) were male. The mean age was 62.9±16.49 years (31–91 years). There were no significant differences between the two groups, according to the hernia side (p=0.282). Thirteen of the elective cases (52%) were operated using open techniques, and 12 cases (48%) were operated using laparoscopic techniques. CONCLUSION: For the comparison of surgical techniques and outcomes, prospective randomized studies should be designed to standardize broad-based surgical techniques.