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KAZANCIOĞLU, RÜMEYZA

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Now showing 1 - 10 of 73
  • PublicationOpen Access
    Comparative Evaluation of Orthostatic Hypotension in Patients with Diabetic Nephropathy.
    (2021-07-20T00:00:00Z) Aytaş, Gamze; Elçioğlu, Ömer C; Kazancıoğlu, Rümeyza; Gürsu, Meltem; Artan, A Serra; Yabacı, Ayşegül; Soysal, PINAR; Bilgi, Kadir; Özçelik, Semra; KAZANCIOĞLU, RÜMEYZA; ELÇİOĞLU, ÖMER CELAL; GÜRSU, MELTEM; YABACI TAK, AYŞEGÜL; SOYSAL, PINAR; ÖZÇELİK, SEMRA
    Introduction: Orthostatic hypotension (OH) affects 5-20% of the population. Our study investigates the presence of OH in diabetic nephropathy (DNP) patients and the factors affecting OH in comparison with nondiabetic chronic kidney disease (NDCKD) patients. Method: Patients presented to the nephrology clinic, and those who consented were included in the study. DNP was defined by kidney biopsy and/or clinical criteria. NDCKD patients of the same sex, age, and eGFR were matched to DNP patients. Demographic parameters and medications were obtained from the records. OH was determined by Mayo clinic criteria. The same researcher used an electronic device to measure blood pressure (BP). All samples were taken and analyzed the same day for biochemical and hematologic parameters and albuminuria. Results: 112 (51 F, 61 M, mean age: 62.56 ± 9.35 years) DNP and 94 (40 F, 54 M, mean age: 62.23 ± 10.08 years) NDCKD patients were included. There was no significant difference between DNP and NDCKD groups in terms of OH prevalence (70.5 vs. 61.7%, p = 0.181). Male patients had significantly higher OH prevalence than female patients (74.7 vs. 60.0%, p = 0.026). There was no significant difference in change in systolic BP between the groups (24.00 [10.00-32.00] mm Hg vs. 24.00 [13.75-30.25] mm Hg, p = 0.797), but the change in diastolic BP was significantly higher in the DNP group (8.00 [2.00-13.00] mm Hg vs. 6.00 [2.00-9.00] mm Hg, p = 0.025). In the DNP group, patients with OH had significantly higher uric acid levels than those without OH (7.18 ± 1.55 vs. 6.36 ± 1.65 mg/dL, p = 0.017). And, 73.7% of patients on calcium channel blockers developed OH (p = 0.015), and OH developed in 80.6% of 36 patients on alpha-blockers (p = 0.049). Conclusion: OH prevalence is very high in CKD, and etiology of CKD does not have a statistically significant effect on the frequency of OH, despite a difference that could be meaningful clinically. Therefore, patients with CKD are checked for OH, with or without concurrent diabetes mellitus. Evaluation of postural BP changes should be a part of nephrology practice.
  • PublicationMetadata only
    Tuberculosis in peritoneal dialysis patients in an endemic region.
    (2011-01-01T00:00:00Z) Gursu, MELTEM; TAYFUR, F; BESLER, M; KAPTANOGULLARI, O; KUCUK, M; AYDIN, Z; BASTURK, T; UZUN, S; KARADAG, S; TATLI, E; SUMNU, A; OZTURK, S; KAZANCIOGLU, RÜMEYZA; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZA
  • PublicationMetadata only
    Paroxysmal nocturnal hemoglobinuria and acute kidney injury: A case report
    (2013-02-01) SUMNU, ABDULLAH; DÖNMEZ, HALIL; GÜRSU, MELTEM; CEBECI, EGEMEN; OZTURK, SAVAS; KILIÇARSLAN, IŞIN; KAZANCIOĞLU, RÜMEYZA; KAZANCIOĞLU, RÜMEYZA
  • PublicationMetadata only
    Alteration of inflammation marker levels with alfa keto analogs in diabetic rats.
    (2022-09-01T00:00:00Z) Bildaci, Y D; Bulut, H; Elcioglu, O C; Gursu, M; Kazancioglu, Rümeyza; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZA
  • PublicationOpen Access
    Peritonitis due to Candida Guilliermondii in a Patient on Continuous Ambulatory Peritoneal Dialysis
    (2015-09-01) TATLI, Emel; Gursu, MELTEM; Aydın, Zeki; UZUN, Sami; KARADAG, Serhat; CEBECI, Egemen; PEHLIVANOGLU, Filiz; SAVAS, Ozturk; Kazancioglu, RÜMEYZA; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZA
    Peritonitis still maintains its importance today as the most significant complication affecting mortality and morbidity in peritoneal dialysis (PD) patients. Although peritonitis is bacterial in 80% of cases, increasing rate of fungal peritonitis has been reported by many studies in recent years. While Candida species (mainly C. parapsilosis, C. albicans and C. tropicalis) are responsible for 70% of cases, other species (Trichosporon, Penicillium, Aspergillus and Acremonium) are very rarely seen. C. guilliermondii has been reported as the cause of peritonitis in PD patients in a few cases. Herein, we present a PD patient with peritonitis due to C. guilliermondii. We aimed to emphasize that non-albicans Candida species should be remembered in PD patients with peritonitis.
  • PublicationMetadata only
    Evaluation of carotis intima media thicknesses in varying degrees of renal failure Böbrek Yetersizliǧinin Farkli Evrelerinde Karotis Intima Media Kalinliklarinin Deǧerlendirilmesi
    (2012-10-05) Gürsu, MELTEM; Aydın, Zeki; UZUN, Sami; KARADAG, Serhat; OGULLAR, Sabri; KIRIS, Adem; SUMNU, Abdullah; tatlı, Emel; GÜRSU, Riza Umar; OZTURK, Savaş; Kazancioǧlu, RÜMEYZA; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZA
  • PublicationMetadata only
    The relationship between ghrelin levels and the presence of helicobacter pylori in the gastric mucosa in uremic patients
    (2013-10-04) Gürsu, MELTEM; UZUN, Sami; KAYA, Ali Hakan; POTUROGLU, Sule; OZTURK, Savas; Kaya, Burcu; KARADAG, Serhat; Aydın, Zeki; OZKAN, Oktay; BAYSAL, Birol; FEYIZOGLU, Hikmet; Kazancioglu, RÜMEYZA; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZA
  • PublicationMetadata only
    Should dalysis be started late? Diyalize geç mi Başlanmali{dotless}?
    (2011-12-01) Gürsu, MELTEM; KAZANCIOĞLU, RÜMEYZA; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZA
  • PublicationOpen Access
    Endothelial Dysfunction and Atherosclerosis in Patients With Autosomal Dominant Polycystic Kidney Disease
    (2021-02-01T00:00:00Z) Büyükbaba, Mitat; Çınar, Ahmet; Tunç, Muhammed; Gürsu, Meltem; Kazancıoğlu, Rümeyza; TUNÇ, MUHAMMED; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZA
    Introduction In this study, we aimed to determine the endothelial dysfunction (ED) and atherosclerosis in patients with autosomal dominant polycystic kidney disease (ADPKD). Materials and methods This study was conducted with 83 subjects (26 male, mean age: 46±11 years) consisted of three groups including ADPKD, hypertension (HT) and healthy control groups. The groups were evaluated in terms of serum endocan and asymmetric dimethylarginine (ADMA) levels, flow-mediated dilatation (FMD), nitroglycerin-mediated dilation (NMD) and carotid intima-media thickness (CIMT). Results Serum endocan and ADMA levels and CIMT were significantly higher while NMD was significantly lower in ADPKD group than control group. FMD and NMD were lower but serum ADMA level was higher in the ADPKD group than HT group; while serum endocan level and CIMT were not significantly different in ADPKD and HT groups. In ADPKD patients, CIMT value and serum endocan and ADMA levels were higher while NMD was lower in patients with eGFR≤60 mL/min/1.73 m2 than patients with eGFR>60 mL/min/1.73 m2. Serum ADMA level was higher and NMD was lower in hypertensive ADPKD patients than non-hypertensive ones. Serum endocan level was higher in ADPKD patients with nephrolithiasis and a negative correlation was detected between serum endocan level and 24-hour urine volume. Conclusions Endothelial dysfunction and atherosclerosis are common conditions in ADPKD patients and it was further reinforced in our study. In order to clarify the relationship between serum endocan level and 24-hour urine volume, which is a remarkable finding in our study, larger studies that including the measurement of urine endocan may be useful.
  • PublicationOpen Access
    COVİD-19 infection in a membranous nephropathy patient treated with rituximab.
    (2020-09-04T00:00:00Z) Elcioglu, Omer Celal; Artan, Ayse Serra; Mirioglu, Safak; Gursu, Meltem; Durdu, Bulent; Koc, Meliha Meric; Okyaltirik, Fatmanur; Gultekin, Mehmet Ali; Kazancioglu, Rümeyza; ELÇİOĞLU, ÖMER CELAL; MİRİOĞLU, ŞAFAK; GÜRSU, MELTEM; DURDU, BÜLENT; MERİÇ KOÇ, MELİHA; OKYALTIRIK, FATMANUR; GÜLTEKİN, MEHMET ALİ; KAZANCIOĞLU, RÜMEYZA
    While COVID-19 pandemic continues to afect our country and most countries in the world, we have to make some changes both in our social life and our approach to healthcare. We have to struggle with the pandemic on one hand and also try to follow up and treat our patients with chronic diseases in the most appropriate way. In this period, one of our group of patients who are challenging us for follow-up and treatment are those who should start or continue to use immunosuppressive therapy. In order to contribute to the accumulation of knowledge in this area, we wanted to report a patient who was followed up with the diagnosis of COVID-19 and had been administered rituximab very recently due to a nephrotic syndrome caused by membranous nephropathy.