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KAZANCIOĞLU, RÜMEYZA

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Now showing 1 - 10 of 28
  • PublicationOpen Access
    Comparative Evaluation of Orthostatic Hypotension in Patients with Diabetic Nephropathy.
    (2021-07-20T00:00:00Z) Aytaş, Gamze; Elçioğlu, Ömer C; Kazancıoğlu, Rümeyza; Gürsu, Meltem; Artan, A Serra; Yabacı, Ayşegül; Soysal, PINAR; Bilgi, Kadir; Özçelik, Semra; KAZANCIOĞLU, RÜMEYZA; ELÇİOĞLU, ÖMER CELAL; GÜRSU, MELTEM; YABACI TAK, AYŞEGÜL; SOYSAL, PINAR; ÖZÇELİK, SEMRA
    Introduction: Orthostatic hypotension (OH) affects 5-20% of the population. Our study investigates the presence of OH in diabetic nephropathy (DNP) patients and the factors affecting OH in comparison with nondiabetic chronic kidney disease (NDCKD) patients. Method: Patients presented to the nephrology clinic, and those who consented were included in the study. DNP was defined by kidney biopsy and/or clinical criteria. NDCKD patients of the same sex, age, and eGFR were matched to DNP patients. Demographic parameters and medications were obtained from the records. OH was determined by Mayo clinic criteria. The same researcher used an electronic device to measure blood pressure (BP). All samples were taken and analyzed the same day for biochemical and hematologic parameters and albuminuria. Results: 112 (51 F, 61 M, mean age: 62.56 ± 9.35 years) DNP and 94 (40 F, 54 M, mean age: 62.23 ± 10.08 years) NDCKD patients were included. There was no significant difference between DNP and NDCKD groups in terms of OH prevalence (70.5 vs. 61.7%, p = 0.181). Male patients had significantly higher OH prevalence than female patients (74.7 vs. 60.0%, p = 0.026). There was no significant difference in change in systolic BP between the groups (24.00 [10.00-32.00] mm Hg vs. 24.00 [13.75-30.25] mm Hg, p = 0.797), but the change in diastolic BP was significantly higher in the DNP group (8.00 [2.00-13.00] mm Hg vs. 6.00 [2.00-9.00] mm Hg, p = 0.025). In the DNP group, patients with OH had significantly higher uric acid levels than those without OH (7.18 ± 1.55 vs. 6.36 ± 1.65 mg/dL, p = 0.017). And, 73.7% of patients on calcium channel blockers developed OH (p = 0.015), and OH developed in 80.6% of 36 patients on alpha-blockers (p = 0.049). Conclusion: OH prevalence is very high in CKD, and etiology of CKD does not have a statistically significant effect on the frequency of OH, despite a difference that could be meaningful clinically. Therefore, patients with CKD are checked for OH, with or without concurrent diabetes mellitus. Evaluation of postural BP changes should be a part of nephrology practice.
  • PublicationOpen Access
    Determinants of mortality in a large group of hemodialysis patients hospitalized for COVID-19
    (2021-01-14T00:00:00Z) Turgutalp, Kenan; Ozturk, Savas; Arici, Mustafa; Eren, Necmi; Gorgulu, Numan; Islam, Mahmut; Uzun, Sami; Sakaci, Tamer; Aydin, Zeki; Sengul, Erkan; Demirelli, Bulent; Ayar, Yavuz; Altiparmak, Mehmet Riza; Sipahi, Savas; Mentes, Ilay Berke; Ozler, Tuba Elif; Oguz, Ebru Gok; Huddam, Bulent; Hur, Ender; Kazancioglu, Rümeyza; Gungor, Ozkan; Tokgoz, Bulent; Tonbul, Halil Zeki; Yildiz, Alaattin; Sezer, Siren; Odabas, Ali Riza; Ates, Kenan; KAZANCIOĞLU, RÜMEYZA
    Background Maintenance hemodialysis (MHD) patients are at increased risk for coronavirus disease 2019 (COVID-19). The aim of this study was to describe clinical, laboratory, and radiologic characteristics and determinants of mortality in a large group of MHD patients hospitalized for COVID-19. Methods This multicenter, retrospective, observational study collected data from 47 nephrology clinics in Turkey. Baseline clinical, laboratory and radiological characteristics, and COVID-19 treatments during hospitalization, need for intensive care and mechanical ventilation were recorded. The main study outcome was in-hospital mortality and the determinants were analyzed by Cox regression survival analysis. Results Of 567 MHD patients, 93 (16.3%) patients died, 134 (23.6%) patients admitted to intensive care unit (ICU) and 91 of the ones in ICU (67.9%) needed mechanical ventilation. Patients who died were older (median age, 66 [57–74] vs. 63 [52–71] years, p = 0.019), had more congestive heart failure (34.9% versus 20.7%, p = 0.004) and chronic obstructive pulmonary disease (23.6% versus 12.7%, p = 0.008) compared to the discharged patients. Most patients (89.6%) had radiological manifestations compatible with COVID-19 pulmonary involvement. Median platelet (166 × 103 per mm3 versus 192 × 103 per mm3, p = 0.011) and lymphocyte (800 per mm3 versus 1000 per mm3, p < 0.001) counts and albumin levels (median, 3.2 g/dl versus 3.5 g/dl, p = 0.001) on admission were lower in patients who died. Age (HR: 1.022 [95% CI, 1.003–1.041], p = 0.025), severe-critical disease clinical presentation at the time of diagnosis (HR: 6.223 [95% CI, 2.168–17.863], p < 0.001), presence of congestive heart failure (HR: 2.247 [95% CI, 1.228–4.111], p = 0.009), ferritin levels on admission (HR; 1.057 [95% CI, 1.006–1.111], p = 0.028), elevation of aspartate aminotransferase (AST) (HR; 3.909 [95% CI, 2.143–7.132], p < 0.001) and low platelet count (< 150 × 103 per mm3) during hospitalization (HR; 1.864 [95% CI, 1.025–3.390], p = 0.041) were risk factors for mortality. Conclusion Hospitalized MHD patients with COVID-19 had a high mortality rate. Older age, presence of heart failure, clinical severity of the disease at presentation, ferritin level on admission, decrease in platelet count and increase in AST level during hospitalization may be used to predict the mortality risk of these patients.
  • PublicationOpen Access
    Availability, coverage, and scope of health information systems for kidney care across world countries and regions.
    (2020-12-22T00:00:00Z) See, Emily J; Bello, Aminu K; Levin, Adeera; Lunney, Meaghan; Osman, Mohamed A; Ye, Feng; Ashuntantang, Gloria E; Bellorin-Font, Ezequiel; Benghanem Gharbi, Mohammed; Davison, Sara; Ghnaimat, Mohammad; Harden, Paul; Htay, Htay; Jha, Vivekanand; Kalantar-Zadeh, Kamyar; Kerr, Peter G; Klarenbach, Scott; Kovesdy, Csaba P; Luyckx, Valerie; Neuen, Brendon; O'Donoghue, Donal; Ossareh, Shahrzad; Perl, Jeffrey; Rashid, Harun Ur; Rondeau, Eric; Syed, Saad; Sola, Laura; Tchokhonelidze, Irma; Tesar, Vladimir; Tungsanga, Kriang; Kazancioglu, Rümeyza; Wang, Angela Yee-Moon; Yang, Chih-Wei; Zemchenkov, Alexander; Zhao, Ming-Hui; Jager, Kitty J; Caskey, Fergus; Perkovic, Vlado; Jindal, Kailash K; Okpechi, Ikechi G; Tonelli, Marcello; Feehally, John; Harris, David C; Johnson, David W; KAZANCIOĞLU, RÜMEYZA
    Background. Health information systems (HIS) are fundamental tools for the surveillance of health services, estimation of disease burden and prioritization of health resources. Several gaps in the availability of HIS for kidney disease were highlighted by the first iteration of the Global Kidney Health Atlas. Methods. As part of its second iteration, the International Society of Nephrology conducted a cross-sectional global survey between July and October 2018 to explore the coverage and scope of HIS for kidney disease, with a focus on kidney replacement therapy (KRT). Results. Out of a total of 182 invited countries, 154 countries responded to questions on HIS (85% response rate). KRT registries were available in almost all high-income countries, but few low-income countries, while registries for non-dialysis chronic kidney disease (CKD) or acute kidney injury (AKI) were rare. Registries in high-income countries tended to be national, in contrast to registries in low-income countries, which often operated at local or regional levels. Although cause of end-stage kidney disease, modality of KRT and source of kidney transplant donors were frequently reported, few countries collected data on patient-reported outcome measures and only half of low-income countries recorded process-based measures. Almost no countries had programs to detect AKI and practices to identify CKD-targeted individuals with diabetes, hypertension and cardiovascular disease, rather than members of high-risk ethnic groups. Conclusions. These findings confirm significant heterogeneity in the global availability of HIS for kidney disease and highlight important gaps in their coverage and scope, especially in low-income countries and across the domains of AKI, non-dialysis CKD, patient-reported outcomes, process-based measures and quality indicators for KRT service delivery.
  • PublicationOpen Access
    Epidemiological features of primary glomerular disease in Turkey: a multicenter study by the Turkish Society of Nephrology Glomerular Diseases Working Group.
    (2020-11-14T00:00:00Z) Turkmen, A; Sumnu, A; Cebeci, E; Yazici, H; Eren, N; Seyahi, N; Dilek, K; Dede, F; Derici, U; Unsal, A; Sahin, G; Sipahioglu, M; Gok, M; Tatar, E; Dursun, B; Sipahi, S; Yilmaz, M; Suleymanlar, G; Ulu, S; Gungor, O; Kutlay, S; Bahcebasi, ZB; Sahin, I; Kurultak, I; Turkmen, K; Yilmaz, Z; Kazancioglu, Rümeyza; Cavdar, C; Candan, F; Aydin, Z; Oygar, DD; Gul, CB; Arici, M; Paydas, S; Taymez, DG; Kucuk, M; Trablus, S; Turgutalp, K; Koc, L; Sezer, S; Duranay, M; Bardak, S; Altintepe, L; Arikan, IH; Azak, A; Odabas, AR; Sahin, GM; Ozturk, S; KAZANCIOĞLU, RÜMEYZA
  • PublicationMetadata only
    Peritoneal Dialysis Use and Practice Patterns: An International Survey Study.
    (2020-08-12T00:00:00Z) Cho, Y; Bello, AK; Levin, A; Lunney, M; Osman, MA; Ye, F; Ashuntantang, GE; Bellorin-Font, E; Gharbi, MB; Davison, SN; Ghnaimat, M; Harden, P; Htay, H; Jha, V; Kalantar-Zadeh, K; Kerr, PG; Klarenbach, S; Kovesdy, CP; Luyckx, V; Neuen, B; O'Donoghue, D; Ossareh, S; Perl, J; Rashid, HU; Rondeau, E; See, EJ; Saad, S; Sola, L; Tchokhonelidze, I; Tesar, V; Tungsanga, K; Kazancioglu, Rümeyza; Yee-Moon, Wang; Yang, CW; Zemchenkov, A; Zhao, MH; Jager, KJ; Caskey, FJ; Jindal, KK; Okpechi, IG; Tonelli, M; Harris, DC; Johnson, DW; KAZANCIOĞLU, RÜMEYZA
  • PublicationOpen Access
    COVİD-19 infection in a membranous nephropathy patient treated with rituximab.
    (2020-09-04T00:00:00Z) Elcioglu, Omer Celal; Artan, Ayse Serra; Mirioglu, Safak; Gursu, Meltem; Durdu, Bulent; Koc, Meliha Meric; Okyaltirik, Fatmanur; Gultekin, Mehmet Ali; Kazancioglu, Rümeyza; ELÇİOĞLU, ÖMER CELAL; MİRİOĞLU, ŞAFAK; GÜRSU, MELTEM; DURDU, BÜLENT; MERİÇ KOÇ, MELİHA; OKYALTIRIK, FATMANUR; GÜLTEKİN, MEHMET ALİ; KAZANCIOĞLU, RÜMEYZA
    While COVID-19 pandemic continues to afect our country and most countries in the world, we have to make some changes both in our social life and our approach to healthcare. We have to struggle with the pandemic on one hand and also try to follow up and treat our patients with chronic diseases in the most appropriate way. In this period, one of our group of patients who are challenging us for follow-up and treatment are those who should start or continue to use immunosuppressive therapy. In order to contribute to the accumulation of knowledge in this area, we wanted to report a patient who was followed up with the diagnosis of COVID-19 and had been administered rituximab very recently due to a nephrotic syndrome caused by membranous nephropathy.
  • PublicationMetadata only
    AN ALTERNATIVE AND UP-TO-DATE RECOMMENDATION FOR A PROPER SITE FOR PARATHYROID TRANSPLANTATION: THE OMENTUM
    (2023-05-26) Ersoy Y. E.; Göncü B. S.; Yücesan E.; Selepcioğlu Kaya H.; Kazancıoğlu R.; Akçakaya A.; ERSOY, YELIZ EMINE; GÖNCÜ, BEYZA SERVET; SELEPCİOĞLU KAYA, HARİKA; KAZANCIOĞLU, RÜMEYZA; AKÇAKAYA, ADEM
  • PublicationOpen Access
    Development of a framework for minimum and optimal safety and quality standards for hemodialysis and peritoneal dialysis
    (2020-03-01T00:00:00Z) Sola, Laura; Levin, Nathan W.; Johnson, David W.; Pecoits-Filho, Roberto; Aljubori, Harith M.; Chen, Yuqing; Claus, Stefaan; Collins, Allan; Cullis, Brett; Feehally, John; Harden, Paul N.; Hassan, Mohamed H.; Ibhais, Fuad; Kalantar-Zadeh, Kamyar; Levin, Adeera; Saleh, Abdulkarim; Schneditz, Daneil; Tchokhonelidze, Irma; Turan Kazancioglu, RÜMEYZA; Twahir, Ahmed; Walker, Robert; Were, Anthony J.O.; Yu, Xueqing; Finkelstein, Fredric O.; KAZANCIOĞLU, RÜMEYZA
    Substantial heterogeneity in practice patterns around the world has resulted in wide variations in the quality and type of dialysis care delivered. This is particularly so in countries without universal standards of care and governmental (or other organizational) oversight. Most high-income countries have developed such oversight based on documentation of adherence to standardized, evidence-based guidelines. Many low- and lower-middle-income countries have no or only limited organized oversight systems to ensure that care is safe and effective. The implementation and oversight of basic standards of care requires sufficient infrastructure and appropriate workforce and financial resources to support the basic levels of care and safety practices. It is important to understand how these standards then can be reasonably adapted and applied in low- and lower-middle-income countries. Keywords: hemodialysis; minimum safety standards; peritoneal dialysis; quality of care.
  • PublicationOpen Access
    Determinants of Mortality Among Elderly Subjects with Chronic Kidney Disease
    (2021-07-01T00:00:00Z) Soysal, Pınar; Heybeli, Cihan; Kazancıoğlu, Rümeyza; SOYSAL, PINAR; KAZANCIOĞLU, RÜMEYZA
  • PublicationOpen Access
    Prevalence of Electrolyte Impairments Among Outpatient Elderly Subjects
    (2022-06-01T00:00:00Z) Heybeli, Cihan; Tan, Semen Gokce; KAZANCIOĞLU, Rümeyza; Smith, Lee; SOYSAL, PINAR; KAZANCIOĞLU, RÜMEYZA; SOYSAL, PINAR
    Objective: To determine the prevalence of different electrolyte imbalances in a cohort of elderly subjects aged ≥65 years, and evaluate associations between each electrolyte imbalance and functional dependence. Methods: We reviewed medical records of consecutive outpatient elderly subjects. Frequency of hyponatremia (serum sodium of 145 mmol/L), hypokalemia (serum potassium of 5.3 mEq/L), hypocalcemia (serum calcium of 10.5 g/dL), hypophosphatemia (serum phosphorus of 4.5 mg/ dL), hypomagnesemia (serum magnesium of 2.3 mg/dL) were assessed. Associations between each electrolyte disorder and Barthel and Lawton-Brody activities of daily living (BADL and IADL) were analyzed. Results: Among the 464 subjects, hyponatremia (11.2%) hypomagnesemia (9.1%) and hypermagnesemia (8.8%) were the most common disorders. Patients with one electrolyte imbalance constituted 30.2% (140 patients) of the cohort, while 44 (9.5%) had two, and 7 (1.5%) patients had ≥2 electrolyte imbalances, concurrently. Calcium, phosphorus, and magnesium disorders were more common among subjects who were 80 years of age or more, compared to those aged 65-79 years, while the frequency of potassium disorders was lower in the former group. Hyponatremia and hypocalcemia were associated with functional dependence based on BADL and IADL scores. Patients with multiple electrolyte abnormalities had a higher risk of functional dependence. Conclusion: Hypomagnesemia was as common as hyponatremia, especially among patients with an age of 80 years or more. Hyponatremia and hypocalcemia appeared to be associated with functional dependence. The higher number of electrolyte abnormality the higher risk of functional dependence. Our results should be confirmed by studies with larger sample sizes.