Person: ALKAN, ALPAY
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Publication Open Access MRI and MR Spectroscopy Features of Heat Stroke: A Case Report(2018-07-01) Yilmaz, TEMEL FATİH; Aralasmak, AYŞE; Toprak, HÜSEYİN; GULER, Serhat; Tüzün, Umit; Alkan, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; ALKAN, ALPAYHeat stroke is the outcome of over heat stress that results in multiorgan dysfunction with a tendency for central nervous system damage. Brain is very sensitive to hyperthermia, especially the cerebellum that has selective vulnerability to heat stroke. There is complex interaction between heat cytotoxicity, coagulation disorder, cytotoxine - mediated systemic inflammatory response causing multiorgan failure, metabolic derangement, and circulatory insufficiency. We reviewed the literature and discussed brain MRI and MR spectroscopy findings of heat stroke, detailed the pathophysiology underlying brain involvement and proposed excitotoxic injury as an alternative mechanism of brain damage in heat stroke.Publication Metadata only Effects of contrast material on the metabolite ratios in single-voxel MR Spectroscopy of intraaxial brain tumors(2012-08-01) Alkan, ALPAY; Burulday, Veysel; Oztanir, Namik; Dogan, Metin; ERBAY, MEHMET FATİH; Kocak, Ayhan; Aralasmak, AYŞE; ALKAN, ALPAY; ÖZTANIR, MUSTAFA NAMIK; ARALAŞMAK, AYŞEAim: The purpose of our study was to determine whether the administration of contrast material affects the results of MR Spectroscopy (MRS) in different intraaxial brain tumors.Publication Open Access The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea(2014-01-01) KILICARSLAN, Rukiye; Alkan, ALPAY; Sharifov, RASUL; Akkoyunlu, MUHAMMED EMİN; Aralasmak, AYŞE; KOCER, Abdulkadir; KART, Levent; ALKAN, ALPAY; SHARIFOV, RASUL; AKKOYUNLU, MUHAMMED EMİN; ARALAŞMAK, AYŞEPurpose: We investigated diffusion alterations in specific regions of the brain in morbid obese, obese, and nonobese OSA patients and searched whether there is a correlation between BMI and ADC values. Materials and methods: DWIs of 65 patients with OSA were evaluated. The patients were classified according to BMI as morbid obese (n = 16), obese (n = 27), and nonobese (control, n = 22) groups. ADC measurements were performed from 24 different regions of the brain in each patient. The relationship of BMI with ADC values was searched. Results: The ADC values in hypothalamus, insular cortex, parietal cortex, caudate nucleus, frontal white matter, and posterior limb of internal capsule were all increased in obese patients (n = 43) compared to control group. The ADC values of midbrain, hypothalamus, orbitofrontal cortex, and parietal cortex were significantly increased in morbid obese compared to obese patients. In obese patients, the degree of BMI was positively correlated with ADC values of orbitofrontal cortex, parietal cortex, and hypothalamus. Conclusion: We observed increasing brain vasogenic edema with increasing BMI, suggesting that the main reason of brain diffusion alteration in patients with OSA could be obesity related.Publication Metadata only Cerebral venous Sinus thrombosis after spinal anesthesia: Case report Spinal Anestezi Sonrasi{dotless} Gelişen Serebral Ven Sinüs Trombozu: Olgu Sunumu(2011-12-01T00:00:00Z) YÜCEL, NESLİHAN; Akgün, Feride Sinem; Tekin, Yusuf Kenan; ALTINAYAR, SİBEL; Alkan, ALPAY; ALKAN, ALPAYPublication Metadata only Neuroimaging depression and anxiety in essential tremor: A diffusion tensor imaging study.(2019-06-27) Sengul, Y; Otcu, H; Ustun, I; Sengul, HS; Cersonsky, T; Alkan, ALPAY; Louis, ED; ALKAN, ALPAYPublication Metadata only Hydrocephalus due to Galen vein aneurysm associated with arteriovenous malformation in an adult patient(2016-01-01) ATASOY, BAHAR; SHARIFOV, RASUL; OTÇU, HAFİZE; ALKAN, ALPAY; ATASOY, BAHAR; SHARIFOV, RASUL; OTÇU TEMUR, HAFİZE; ALKAN, ALPAYPublication Metadata only Sleep Disturbances in Essential Tremor: A pilot investigation of the related brain microstructural changes using diffusion tensor imaging(2019-12-01T00:00:00Z) Alkan, Alpay; ALKAN, ALPAYSengul Y., Otcu H., Ustun I., Sengul H., Alkan A., -Sleep Disturbances in Essential Tremor: A pilot investigation of the related brain microstructural changes using diffusion tensor imaging-, MOVEMENT DISORDERS, vol.34, pp.S829, 2019Publication Metadata only Detecting the Shape Differences of the Corpus Callosum in Behçet-s Disease by Statistical Shape Analysis(2011-05-01T00:00:00Z) ÇOLAK, CEMİL; Ercan, Ilker; Dogan, Metin; Ozdemir, Senem Turan; ŞENER, SERPİL; Alkan, ALPAY; ALKAN, ALPAYPublication Metadata only Evaluation of CSF flow metrics in patients with communicating hydrocephalus and idiopathic intracranial hypertension(2019-05-01) Yilmaz, TEMEL FATİH; Aralasmak, AYŞE; Toprak, HÜSEYİN; MEHDI, Elnur; KOCAMAN, Gulsen; Kurtcan, SERPİL; Kaya, MEHMET ONUR; Alkan, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; KURTCAN, SERPİL; KAYA, MEHMET ONUR; ALKAN, ALPAYPurpose To search for CSF dynamics of idiopathic intracranial hypertension (IIH) and communicating hydrocephalus and any correlation between MRI findings, CSF metrics and CSF opening pressure in IIH.Publication Metadata only Diffusion-Weighted Images Differentiate Benign From Malignant Thyroid Nodules(2010-01-01T00:00:00Z) ERDEM, GÜLNUR; Erdem, Tamer; Karakas, Hakki Muammer; Mutlu, Deniz Yakar; Firat, Ahmet Kemal; ŞAHİN, İBRAHİM; Alkan, ALPAY; ALKAN, ALPAYPurpose: To reveal the possible role of diffusion-weighted images (DWI) in the differential diagnosis of benign and malignant thyroid nodules by comparing the results of fine-needle aspiration cytology (FNAC).