Person: ELMADAĞ, NUH MEHMET
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Publication Open Access Comparison of Small-diameter-hole and Traditional Microfracture in Cartilage Repair and the Effect of Adding a Hyaluronic Acid-based Acellular Matrix Scaffold: An Animal Study(2021-03-01T00:00:00Z) UÇAN, VAHDET; YILDIZ, FATİH; ELMADAĞ, Nuh Mehmet; UZER, GÖKÇER; GÜZEL, YUNUS; TOK, OLGU ENİS; Mukaddes, E.; UÇAN, VAHDET; YILDIZ, FATİH; ELMADAĞ, NUH MEHMET; UZER, GÖKÇER; TOK, OLGU ENİS; EŞREFOĞLU, MUKADDESObjective: Since, there is no standardized technique for the treatment of focal cartilage defects that can recreate original cartilage tissue; researchers continue to explore and evaluate various treatment modalities. This study compared post-operatke healing of cartilage defects after treatment with small-diameter-hole microfracture (SDHM) technique with that of traditional microfracture technique. The effects of the hole density and augmentation with hyaluronic acid-based acellular matrix (HA-based AM) on cartilage healing were also investigated. Methods: Articular cartilage defects measuring 5 mm in diameter and 3 mm in depth were created in each femoral trochlear groove of 21 New Zealand rabbits. Rabbits were assigned to seven groups comprising six knees each. The rabbits were sacrificed 12 weeks later, and the regenerated cartilage was harvested for histological evaluation using the Wakitani scoring system. Results: All defects were filled with regenerated tissue macroscopically. Group I (14; range 10-14 points) had significantly higher Wakitani score than in groups VI (6; range 1-11 points) and VII (5; range 3-10 points) (p=0.043 and p=0.016, respectively). No significant differences were observed among the other groups. Augmentation with HA-based AM did not contribute to cartilage healing. Conclusion: Improved cartilage healing was observed with increasing SDHM density than with traditional microfracture technique. SDHM combined with HA-based AM implantation did not improve the quality of the regenerated cartilage.Publication Metadata only The Effects of Core Stabilization Exercises on Pulmonary Function, Functional Capacity and Peripheral Muscle Strength in Children with Adolescent Idiopathic Scoliosis.(2020-09-07T00:00:00Z) Yıldırım, Sefa; Özyılmaz, Semiramis; Elmadağ, Nuh Mehmet; YILDIRIM, SEFA; ÖZYILMAZ, SEMIRAMIS; ELMADAĞ, NUH MEHMETPublication Metadata only Effects of Core Stabilization Exercises on Pulmonary Function, Respiratory Muscle Strength, Peripheral Muscle Strength, Functional Capacity, and Perceived Appearance in Children With Adolescent Idiopathic Scoliosis: A Randomized Controlled Trial(2022-08-01T00:00:00Z) Yıldırım, Sefa; Özyılmaz, Semiramis; Elmadağ, Nuh Mehmet; Yabacı Tak, Ayşegül; YILDIRIM, SEFA; ÖZYILMAZ, SEMIRAMIS; ELMADAĞ, NUH MEHMET; YABACI TAK, AYŞEGÜLObjectiveThe aim of the study was to investigate the effects of core stabilization exercises on pulmonary function, respiratory muscle strength, peripheral muscle strength, walking capacity, andperceived appearancein children with adolescent idiopathic scoliosis.DesignThis is an evaluator-blinded, randomized controlled trial. A total of 30 patients were randomly allocated to either a training group (n= 15, age = 13.8 ± 2.8 yrs, Cobb angle = 19.3 ± 6 degrees, Risser sign:n(1)= 1;n(2–4)= 14) or a control group (n= 15, age = 15.8 ± 3.4 yrs, Cobb angle = 20.8 ± 7.9 degrees, Risser sign:n(1)= 1;n(2–4)= 14). The training group received core stabilization exercises in addition to the traditional scoliosis exercises for 8 wks. The control group only received the traditional scoliosis exercises for 8 wks. Spirometry, maximal inspiratory and expiratory pressures, 6-min walking test, peripheral muscle strength, and the Walter Reed Visual Assessment Scale were assessed at the beginning and end of the study.ResultsThe training group showed statistically significant improvements in maximal inspiratory pressure, maximum expiratory pressure, and Walter Reed Visual Assessment Scale score (respectively, mean changes = 17.4 ± 5.2 cmH2O; 10.6 ± 4.3 cmH2O; 2.4 ± 1.6), which were significantly larger compared with the control group (P< 0.05).ConclusionsCore stabilization exercises given in addition to the traditional scoliosis exercise can improve respiratory muscle strength andperceived appearancein patients with adolescent idiopathic scoliosis.Publication Metadata only Adölesan İdiyopatik Skolyozlu Çocuklarda Core Stabilizasyon Egzersizlerinin Gövde Rotasyon Açısı Üzerine Etkisi(2021-05-08T00:00:00Z) YILDIRIM, SEFA; MANZAK, AYŞE SENA; ÖZYILMAZ, SEMİRAMİS; ELMADAĞ, NUH MEHMET; YILDIRIM, SEFA; MANZAK, AYŞE SENA; ÖZYILMAZ, SEMIRAMIS; ELMADAĞ, NUH MEHMETPublication Metadata only Vertical Versus Pfannenstiel Incision-Modified Stoppa Approach in the Treatment of Acetabular Fractures(2024-03-01) Kara D.; ELMADAĞ N. M.; Ali J.; Misir A.; Cetin H.; DEMİRKIRAN C. B.; Mraja H.; Pulatkan A.; ELMADAĞ, NUH MEHMET; ALİ, JOTYAR; ÇETİN, HUZEYFE; DEMİRKIRAN, CEMİL BURAKOBJECTIVES:The aims of this study were to compare the patient and fracture characteristics, radiological, functional, and quality of life outcomes; the need for a lateral window approach and requirement of total hip arthroplasty; and complications in patients with simple and complex acetabular fractures who underwent a modified Stoppa approach through vertical and Pfannenstiel incisions.METHODS:Design:This was a retrospective comparison study.Setting:Level 1 trauma center.Patient Selection Criteria:Patients with acetabular fractures (A-O-/-O-T-A type 62A-B-C) treated with vertical (group V) or Pfannenstiel (group P) incision-modified Stoppa approach between 2010 and 2020 were included.Outcome Measures and Comparisons:Patient characteristics, radiological evaluations (reduction quality and posttraumatic osteoarthritis), patient functional outcomes [12-item Short-Form Survey (SF-12) physical component score, SF-12 mental component score, Harris Hip Score, and Merle d\"Aubigné-Postel], approach modifications and stratification by fracture type and complications were compared between those treated with vertical or Pfannenstiel incisions.RESULTS:One hundred four patients (mean age of 38.5 ± 14.3 years) were included. There was no significant difference between the Pfannenstiel or vertical groups regarding patient and fracture characteristics (P = 0.137), postoperative reduction quality (P = 0.130), or the mean functional and quality of life outcome scores at the last follow-up (P = 0.483 for the Harris Hip Score, P = 0.717 for the Merle d\"Aubigné-Postel score, P = 0.682 for the SF-12 physical component score, and P = 0.781 for the SF-12 mental component score). In group P, significantly more patients needed additional lateral incisions (40.8% vs. 10.9%; P 0.001) and total hip replacement procedures (12.2% vs. 1.8%; P = 0.049). The total, early, and late complication rates were significantly higher in group P (P 0.001, P = 0.034, and P = 0.049, respectively).CONCLUSIONS:Pfannenstiel incision was associated with higher complication rates than vertical incision in acetabular fractures treated through a modified Stoppa approach. Fracture complexity is associated with the need for a lateral window approach and total hip arthroplasty, as well as a worse functional and radiological outcome regardless of incision type. However, it was not associated with the development of intraoperative or postoperative complications.LEVEL OF EVIDENCE:Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.