Person: KIZILARSLAN HANÇER, ÇAĞLA
16 results
Search Results
Now showing 1 - 10 of 16
Publication Metadata only Evaluation of cytotoxic and antioxidant potential of Dittrichia viscosa (L.) Greuter used in traditional medicine(2021-08-01T00:00:00Z) SEVGİ, ECE; DAĞ, AYDAN; Kizilarslan-Hancer, Cagla; ATASOY, SEZEN; ZENGİN KURT, BELMA; Aksakal, Oznur; SEVGİ, ECE; DAĞ, AYDAN; KIZILARSLAN HANÇER, ÇAĞLA; ATASOY, SEZEN; ZENGİN KURT, BELMAEthnopharmacological relevance: Dittrichia viscosa (L.) Greuter (& ldquo;Sari ot, Yapis & cedil;kan andiz otu & rdquo; in Turkish) is a medicinal plant that has been traditionally used in the Mediterranean area. This plant is used by the local population for the treatment of cancer. Investigation of their biological activities is therefore very important to be supported by scientific basis for traditional use.Publication Metadata only An ethnobotanical survey of medicinal plants in Biga (Canakkale-Turkey)(2022-07-01T00:00:00Z) SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLA; Akkaya, Muhammet; Altundag-Cakire, Ernaz; Bilytikkilic-Altinbasak, Beall; KIZILARSLAN HANÇER, ÇAĞLAPublication Open Access Traditional knowledge of wild edible plants of Biga (Çanakkale), Turkey(2020-01-01T00:00:00Z) Hançer, Çaǧla Kizilarslan; Sevgi, Ece; Çakir, Ernaz Altundaǧ; Akkaya, Muhammet; KIZILARSLAN HANÇER, ÇAĞLA; SEVGİ, ECE; BÜYÜKKILIÇ ALTINBAŞAK, BETÜLPublication Metadata only Comparison of Species Richness and Diversity at Natural Stands and Plantations of Stone Pine (Pinus pinea L.)(2017-10-01) ALTUNDAG ÇAKIR, ERNAZ; TECIMEN, HUSEYIN BARIS; SEVGI, ORHAN; Akkaya, Muhammed; SEVGİ, ECE; SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLAIn recent years, plantation areas are criticized for the reduction of species diversity and deterioration of habitat quality. The effects of stone pine (Pinus pinea L.) plantations on species diversity were investigated in this study to enlighten the situation. A total of 73 sample areas were investigated from north western Turkey (Biga-Canakkale) region, including 25 native and 48 plantation areas. Taxa of the sample areas were identified and species diversity and similarity analysis was performed. We found significantly lower number of plant species at plantation areas than natural areas at Pekmezli (4 yr old stand) and Kargi Ciftligi (25 yr old stand) blocks with p values 0.016 and 0.005 respectively. Shannon-Wiener index values of plantation areas were found to be 3.04 and 3.23 with p values 0.027 and 0.007 in Pekmezli and Kargi Ciftligi respectively. The Sorensen similarity analysis showed that, there was a higher similarity pattern in natural areas than in plantation areas. It was concluded that the plantation activities only in the areas of Pekmezli and Kargi Ciftligi negatively affected the number of species and diversity index values.Publication Metadata only As A Living Culture of Treditional Herbal Coffee in Turkey: Chickpea Coffee(2019-05-01) SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLA; ALTUNDAĞ ÇAKIR, ERNAZ; Akkaya, Muhammet; KIZILARSLAN HANÇER, ÇAĞLA; SEVGİ, ECEPublication Metadata only ÇAM (KIZILÇAM) UÇUCU YAĞI(2020-11-01T00:00:00Z) ZORLU, NİHAL; BÜYÜKKILIÇ ALTINBAŞAK, BETÜL; SEVGİ, ECE; SALİHLER, KEVSER; KIZILARSLAN HANÇER, ÇAĞLA; KARTAL, MURAT; TOPÇU, GÜLAÇTI; BÜYÜKKILIÇ ALTINBAŞAK, BETÜL; SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLA; KARTAL, MURAT; TOPÇU, GÜLAÇTIPublication Open Access Differential anti-proliferative and apoptotic effects of lichen species on human prostate carcinoma cells(2020-09-01T00:00:00Z) Goncu, Beyza; SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLA; Gokay, Guzin; ÖZTEN KANDAŞ, NUR; GÖNCÜ, BEYZA SERVET; SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLA; ÖZTEN KANDAŞ, NURLichens are stable symbiotic associations between fungus and algae and/or cyanobacteria that have different biological activities. Around 60% of anti-cancer drugs are derived from natural resources including plants, fungi, sea creatures, and lichens. This project aims to identify the apoptotic effects and proliferative properties of extracts ofBryoria capillaris (Ach.) Brodo&D.Hawksw,Cladonia fimbriata (L.) Fr.,Evernia divaricata (L.) Ach.,Hypogymnia tubulosa (Schaer.) Hav.,Lobaria pulmonaria (L.) Hoffm., andUsnea florida (L.) Weber ex Wigg. lichen species on prostate cancer cells. Lichen extracts were performed by ethanol, methanol, and acetone separately by using the Soxhlet apparatus and the effects of the extracts on cell viability, proliferation, and apoptosis were measured with the utilization of MTT, LDH assay, Annexin V assay, and Western Blot. Findings of our study revealed a positive correlation between the elevation of cell sensitivity and the increase in the treatment doses of the extract in that higher doses applied reverberate to higher cell sensitivity. A similar correlation was also identified between cell sensitivity elevation and the duration of the treatment. Evidence in our study have shown the existence of an anti-proliferative effect in the extracts ofBryoria capillaris,Evernia divaricata (L.) Ach.,Hypogymnia tubulosa (Schaer.) Hav.,Lobaria pulmonaria (L.) Hoffm., andUsnea florida (L.) Weber ex Wigg., while a similar effect was not observed in the extracts ofCladonia fimbriata.Evernia divaricatainduced anti-proliferative and apoptotic effects in PC-3 cells,whichinduced apoptotic cell death by both extrinsic and intrinsic pathways.Hypogymnia tubulosahas been shown to have anti-proliferative and apoptotic effects in all extractions methods and our findings identified that both the percentage of the apoptotic cells and apoptotic protein expressions recorded an increase at lower treatment concentrations. AlthoughLobaria pulmonariais known to have significant cytotoxic effects, we did not observe a decrease in cell proliferation. Indeed, proliferation marker proliferating cell nuclear antigen (PCNA) protein expression levels have shown an increase in all extracts, whileUsnea florida exhibitedapoptosis induction and slight proliferation reduction in extract treatments with lower concentrations. We tested 18 extracts of six lichen species during our study. Of these,Evernia divaricataandHypogymnia tubulosademonstrated significant apoptotic activity on prostate cancer cells including at low concentrations, which implies that it is worth pursuing the biologically active lead compounds of these extracts on prostate cancerin vitro. Further corroboratory studies are needed to validate the relative potential of these extracts as anti-metastatic and anti-tumorigenic agents.Publication Metadata only Biga’da (Çanakkale) Geleneksel Kullanımı Olan Bitkilerin Yöresel Adları ve Adlandırma Yaklaşımları(2018-03-01) SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLA; Akkaya, Muhammed; ALTUNDAĞ ÇAKIR, ERNAZ; SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLAPublication Metadata only Çam (Anadolu Karaçamı) Uçucu YağıPine Nigra (Anatolian Black Pine) Essential Oil(2020-10-01T00:00:00Z) ZORLU, NİHAL; KIZILARSLAN HANÇER, ÇAĞLA; SALİHLER, KEVSER; SEVGİ, ECE; BÜYÜKKILIÇ ALTINBAŞAK, BETÜL; TOPÇU, GÜLAÇTI; KARTAL, MURAT; BÜYÜKKILIÇ ALTINBAŞAK, BETÜL; SEVGİ, ECE; KIZILARSLAN HANÇER, ÇAĞLA; KARTAL, MURAT; TOPÇU, GÜLAÇTIPublication Metadata only ÇAM (FISTIK ÇAMI) UÇUCU YAĞI(2020-11-01T00:00:00Z) SEVGİ, ECE; BÜYÜKKILIÇ ALTINBAŞAK, BETÜL; ZORLU, NİHAL; SALİHLER, KEVSER; KIZILARSLAN HANÇER, ÇAĞLA; KARTAL, MURAT; TOPÇU, GÜLAÇTI; SEVGİ, ECE; BÜYÜKKILIÇ ALTINBAŞAK, BETÜL; KIZILARSLAN HANÇER, ÇAĞLA; KARTAL, MURAT; TOPÇU, GÜLAÇTI