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GÜRSES, HÜLYA NILGÜN

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HÜLYA NILGÜN
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Start date: 2020 × End date: 2023 × Author: Zeren, Melih ×

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    Do Pulmonary and Extrapulmonary Features Differ Among Cystic Fibrosis, Primary Ciliary Dyskinesia and Healthy Children?
    (2020-09-02T00:00:00Z) Kulli, Hilal; Gürses, Hülya Nilgün; Zeren, Melih; Ucgun, HİKMET; Çakır, Erkan; DENİZOĞLU KÜLLİ, HİLAL; GÜRSES, HÜLYA NILGÜN; UÇGUN, HİKMET; ÇAKIR, ERKAN
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    PublicationOpen Access
    Atrial Fibrillation Impact Questionnaire (AFImpact): Validity and reliability of the Turkish version
    (2021-07-01T00:00:00Z) Zeren, Melih; Demir, Rengin; Karci, Makbule; Yigit, Zerrin; Uzunhasan, Isil; GÜRSES, Hülya Nilgün; GÜRSES, HÜLYA NILGÜN
    Objective: Guidelines recommend measuring and addressing health-related quality of life in the management of atrial fibrillation (AF); however, a disease-specific questionnaire is lacking for the Turkish language. Our aim was to translate and adapt the Atrial Fibrillation Impact Questionnaire (AFImpact) into Turkish and to explore its psychometric properties. Methods: This cross-sectional study was conducted in two phases, including the translation and cultural adaptation of AFImpact into Turkish language and the analysis of psychometric properties of the translated questionnaire. 98 patients diagnosed with AF were evaluated using the Turkish version of AFImpact, Short Form-36 (SF-36) and Pittsburg Sleep Quality Index (PSQI). Reliability, validity, and factor structure of the Turkish version of AFImpact was explored. Results: Cronbach's alpha coefficients for vitality, emotional distress, and sleep domains of AFImpact was 0.956, 0.955, and 0.819, respectively, indicating good-to-excellent internal consistency. No significant difference was detected between the initial and retest scores, and intraclass correlation coefficients of each domain varied between 0.991 and 0.996, indicating excellent test-retest reliability. Each domain of AFImpact highly correlated with similar domains of SF-36 and PSQI, having correlation coefficients between -0.484 and -0.699. AFImpact was able to discriminate between the patients in different functional classes, confirming know-groups validity. Factor analysis revealed AFImpact had the same factorial structure as the original questionnaire. Conclusion: The Turkish version of AFImpact is a valid and reliable questionnaire for evaluating health-related quality of life in patients with AF.
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    Bronşektazili Çocuklarda ve Sağlıklı Kontrollerde Otur-Kalk Testinin Fonksiyonel Egzersiz Kapasitesini Değerlendirme Amacıyla Kullanımı
    (2020-03-05T00:00:00Z) Zeren, Melih; Çakır, Erkan; Uçgun, Hikmet; Denizoğlu Külli, Hilal; Gürses, Hülya Nilgün; GÜRSES, HÜLYA NILGÜN; DENİZOĞLU KÜLLİ, HİLAL; UÇGUN, HİKMET; ÇAKIR, ERKAN
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    Bronşektazili Çocuklarda Fonksiyonel Kapasitenin Belirleyicileri
    (2021-12-05T00:00:00Z) Kaya, Meltem; Uçgun, Hikmet; Denizoğlu Külli, Hilal; Zeren, Melih; Çakır, Erkan; Gürses, Hülya Nilgün; KAYA, MELTEM; UÇGUN, HİKMET; ÇAKIR, ERKAN; GÜRSES, HÜLYA NILGÜN
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    Does the effect of comprehensive respiratory physiotherapy home-program differ in children with cystic fibrosis and non-cystic fibrosis bronchiectasis?
    (2022-01-01T00:00:00Z) GÜRSES, Hülya Nilgün; Ucgun, Hikmet; Zeren, Melih; Denizoglu Kulli, Hilal; ÇAKIR, Erkan; GÜRSES, HÜLYA NILGÜN; ÇAKIR, ERKAN
    © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Bronchiectasis is a form of airway damage as a consequence of endobronchial infection and inflammation and may be present in different diseases. The underlying aetiologies include both cystic fibrosis (CF) and a group of non-cystic fibrosis diseases (NCFB) such as immunodeficiency, primary ciliary dyskinesia, or severe pulmonary infection. Although children with CF and non-cystic fibrosis bronchiectasis (NCFB) have many similar clinical features, their responses to exercise may be different. The aim of this study was to compare the efficacy of a comprehensive respiratory physiotherapy (CRP) home-program in children with CF and NCFB. Thirty children with CF and thirty children with NCFB were included in the study. Both groups performed the CRP home-program twice daily for 8 weeks. Pulmonary function, exercise capacity, and respiratory and peripheral muscle strength were assessed at baseline and after 8 weeks of training. Both groups experienced significant improvements in pulmonary function, exercise capacity, and respiratory and peripheral muscle strength (p < 0.001). Maximum expiratory pressure, exercise capacity, and peripheral muscle strength were further improved in NCFB group compared to CF (p < 0.05); however, there was a great variability in the improvements for each variable. Conclusion: CRP is beneficial both for children with CF and NCFB and adherence to the program was high in both groups.What is Known:• Different physiotherapy approaches in the management of non-cystic fibrosis bronchiectasis have been based on the experience gained from the research studies performed in cystic fibrosis.• Although having similar pathophysiology, these two diseases show variation in some pulmonary and extrapulmonary features.What is New:• The respiratory muscle strength and the efficacy of comprehensive respiratory physiotherapy have been compared for the first time in children with cystic fibrosis and non-cystic fibrosis bronchiectasis.• Comprehensive respiratory physiotherapy provides higher increases in children with non-cystic fibrosis bronchiectasis in exercise capacity and expiratory and peripheral muscle strength; however, there was a great variability in these improvements. Nevertheless, it can be concluded that both groups significantly benefited from the CRP program.
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    PublicationOpen Access
    Sit-to-stand test in children with bronchiectasis: Does it measure functional exercise capacity?
    (2020-09-01T00:00:00Z) Zeren, Melih; Gürses, Hülya Nilgün; Denizoğlu Külli, Hilal; Uçgun, Hikmet; Çakır, Erkan; GÜRSES, HÜLYA NILGÜN; DENİZOĞLU KÜLLİ, HİLAL; UÇGUN, HİKMET; ÇAKIR, ERKAN
    Background Similar to six-minute walk test (6MWT), sit-to-stand test (STST) is a self-paced test which elicits sub-maximal effort; therefore, it is suggested as an alternative measurement for functional exercise capacity in various pulmonary conditions including COPD and cystic fibrosis. We aimed to investigate the association between 30-second STST (30s-STST) and 6MWT in both children with bronchiectasis (BE) and their healthy counterparts, as well as exploring cardiorespiratory burden and discriminative properties of both tests. Methods Sixty children (6 to 18-year-old) diagnosed with non-cystic fibrosis BE and 20 age-matched healthy controls were included. Both groups performed 30s-STST and 6MWT. Test results, and heart rate, SpO2 and dyspnea responses to tests were recorded. Results Univariate analysis revealed that 30s-STST was able to explain 52% of variance in 6MWT (r = 0.718, p<0.001) in BE group, whereas 20% of variance in healthy controls (r = 0.453, p = 0.045). 6MWT elicited higher changes in heart rate and dyspnea level compared to 30s-STST, indicating it was more physically demanding. Both 30s-STST (21.65±5.28 vs 26.55±3.56 repetitions) and 6MWT (538±85 vs 596±54 m) were significantly lower in BE group compared to healthy controls (p<0.01). Receiver operating characteristic (ROC) curve analysis revealed an area under the ROC curve (UAC) of 0.765 for 30s-STST and 0.693 for 6MWT in identifying the individuals with or without BE (p<0.05). Comparison between AUCs of 30s-STST and 6MWT yielded no significant difference (p = 0.466), indicating both tests had similar discriminative properties. Conclusions 30s-STST is found to be a valid alternative measurement for functional exercise capacity in children with BE.
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    Validity and reliability of the Turkish version of breathlessness beliefs questionnaire
    (2022-01-01T00:00:00Z) Gürses, Hülya Nilgün; Saka, Seda; Zeren, Melih; Bayram, Mehmet; GÜRSES, HÜLYA NILGÜN
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    PublicationOpen Access
    Cut-off values of 6-min walk test and sit-to-stand test for determining symptom burden in atrial fibrillation
    (2022-01-01T00:00:00Z) Zeren, Melih; Karci, Makbule; DEMİR, Rengin; GÜRSES, Hülya Nilgün; OKTAY, Veysel; UZUNHASAN, Işıl; YİĞİT, Zerrin; GÜRSES, HÜLYA NILGÜN
    Background Since symptomatology is a major predictor of quality of life and an endpoint for the management of atrial fbrillation (AF), practical approaches for objectively interpreting symptom burden and functional impairment are needed. Aims We aimed to provide cut-of values for two frequently used feld tests to be able to objectively interpret symptom burden in atrial fbrillation. Methods One hundred twenty-fve patients with AF were evaluated with European Heart Rhythm Association (EHRA) score, 6-min walk test (6MWT), 30 s sit-to-stand test (30 s-STST), Short-Form 36 (SF-36), International Physical Activity Questionnaire-Short Form (IPAQ-SF), and spirometry. Patients with EHRA 1 were classifed as “asymptomatic”, and those with EHRA 2–4 as “symptomatic”. Cut-of values of 6MWT and 30 s-STST for discriminating between these patients were calculated. Results The optimal cut-of value was “450 m” for 6MWT (sensitivity: 0.71; specifcity of 0.79) and “11 repetitions” for 30 s-STST (sensitivity 0.77; specifcity of 0.70). Area under ROC curve was 0.75 for both tests (p<0.001). Subgroup analysis revealed patients below cut-of values also had worse outcomes in SF-36, IPAQ-SF, and spirometry. Conclusions In patients with AF, walking < 450 m in 6MWT or performing < 11 repetitions in 30 s-STST indicates increased symptom burden, as well as impaired exercise capacity, quality of life, physical activity participation, and pulmonary function. These cut-of values may help identifying patients who may require adjustments in their routine treatment or who may beneft from additional rehabilitative approaches.
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    Postural stability and fall risk in patients with obstructive sleep apnea: a cross-sectional study
    (2021-02-01T00:00:00Z) Yilmaz Gokmen, Gulhan; GÜRSES, Hülya Nilgün; Zeren, Melih; ÖZYILMAZ, Semiramis; Kansu, Abdullah; Akkoyunlu, Muhammed Emin; GÜRSES, HÜLYA NILGÜN; ÖZYILMAZ, SEMIRAMIS
    Purpose Nocturnal hypoxia and daytime sleepiness resulting from fragmented sleep may impair the ability of postural stability in subjects with OSA. This study investigates the effect of disease severity on postural stability and whether or not it poses a fall risk in individuals with obstructive sleep apnea (OSA).
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    PublicationOpen Access
    Effect of Gender and Physical Activity Level on Sit-to-Stand Test Performance Among Young Adults
    (2020-07-01T00:00:00Z) Gürses, Hülya Nilgün; Denizoğlu Külli, Hilal; Durgut, Elif; Zeren, Melih; GÜRSES, HÜLYA NILGÜN; DENİZOĞLU KÜLLİ, HİLAL; DURGUT, ELİF
    Objective: Our study aimed to determine the sit-to-stand (STS) test performance and physical activity levels of young adults and investigate the relationship of STS tests with gender and physical activity levels. Methods: Sixty volunteers randomly performed the 5xSTS, 10sSTS, 30sSTS and 60sSTS tests. Fatigue was rated using the Borg category ratio scale. Physical activity level and weekly energy expenditure of volunteers were calculated using the International Physical Activity Questionnaire. Results: The 5xSTS, 10sSTS, 30sSTS and 60sSTS test scores were statistically different between genders (p=0.004; p=0.002; p=0.000; p=0.000, respectively). Fatigue levels after STS tests did not show any difference between genders (p=0.636; p=0.295; p=0.888; p=0.150, respectively). Weekly energy expenditures were positively correlated with STS tests except 5xSTS test (r=-0.458, p=0.000; r=0.427, p=0.001; r=0.606, p=0.000; r=0.545, p=0.000, respectively). All STS tests had significant differences between participants with moderate or high physical activity level (p=0.016; p=0.007; p=0.000; p=0.000, respectively). Conclusion: Our study shows that STS tests scores correlate to gender and physical activity levels in young adults.