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YILDIRIM, YAVUZ SELİM

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YAVUZ SELİM
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Now showing 1 - 10 of 18
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    Eustachian Tube Function in Patients Receiving Continuous Positive Airway Pressure Treatment for Sleep Apnea Syndrome
    (2010-12-01) AKSOY, Fadlullah; Yildirim, YAVUZ SELİM; Ozturan, ORHAN; VEYSELLER, Bayram; Cuhadaroglu, Caglar; AKSOY, FADLULLAH; YILDIRIM, YAVUZ SELİM; ÖZTURAN, ORHAN
    Objective: We evaluated eustachian tube (ET) function in patients using continuous positive airway pressure (CPAP).
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    Tension pneumocephalus: an extremely small defect leading to an extremely serious problem
    (2013-11-01) Aksoy, Fadlullah; Dogan, REMZİ; Ozturan, ORHAN; TUGRUL, Selahattin; Yildirim, YAVUZ SELİM; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; YILDIRIM, YAVUZ SELİM
    Background: Pneumocephalus is a pathology characterized by air influx into the intracranial region. It may occur after head trauma and rarely after endoscopic sinus surgery. As the amount of air increases, this can cause neurological disorders with a mass effect and this condition is called tension pneumocephalus.
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    The Effect of Topical Cefepime Solution on Outer Hair Cell Function of Rats
    (2011-01-01) Apuhan, Tayfun; Yildirim, YAVUZ SELİM; Aksoy, Fadlullah; BALIKCI, Hasan Huseyin; Kaya, Mehmet Onur; YILDIRIM, YAVUZ SELİM; AKSOY, FADLULLAH
    Objectives: The current study was designed to investigate the ototoxic effect of topical cefepime solution on the outer cell function of cochlea by measuring distortion product otoacoustic emission (DPOAE) amplitudes.
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    [Distortion product otoacoustic emissions results in children with middle ear effusion]. Seröz otitis mediali çocuklarda distorsiyon ürünü otoakustik emisyon sonuçlari.
    (2010-01-01T00:00:00Z) AKSOY, Fadlullah; Yildirim, YAVUZ SELİM; VEYSELLER, Bayram; DEMIRHAN, Hasan; Ozturan, ORHAN; AKSOY, FADLULLAH; YILDIRIM, YAVUZ SELİM; ÖZTURAN, ORHAN
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    [Patterns of cervical metastasis from squamous cell carcinoma of the head and neck]. Baş ve boyun yassi epitel hücreli kanserlerinde boyun yayilim modelleri.
    (2010-01-01T00:00:00Z) AKSOY, Fadlullah; VEYSELLER, Bayram; BINAY, Omer; APUHAN, Tayfun; Yildirim, YAVUZ SELİM; Ozturan, ORHAN; AKSOY, FADLULLAH; YILDIRIM, YAVUZ SELİM; ÖZTURAN, ORHAN
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    Reduced olfactory bulb volume and diminished olfactory function in total laryngectomy patients: A prospective longitudinal study
    (2012-05-01) VEYSELLER, Bayram; OZUCER, Berke; AKSOY, Fadlullah; Yildirim, YAVUZ SELİM; GURBUZ, Defne; BALIKCI, Hasan Huseyin; Ozturan, ORHAN; AKSOY, FADLULLAH; YILDIRIM, YAVUZ SELİM; ÖZTURAN, ORHAN
    Background: This study was designed to investigate the effects of total laryngectomy on olfactory bulb (OB) volume and olfactory function prospectively. A prospective, longitudinal, randomized study was performed.
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    Betahistine Exacerbates Amikacin Ototoxicity
    (2015-04-01) AKSOY, Fadlullah; Dogan, REMZİ; Ozturan, ORHAN; Yildirim, YAVUZ SELİM; VEYSELLER, Bayram; Yenigun, ALPER; OZTURK, Burak; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; YILDIRIM, YAVUZ SELİM; YENİGÜN, ALPER
    Objective: Betahistine augments cochlear blood flow and is currently used as an efficient therapeutic agent. Amikacin is used in a wide range of areas, but its ototoxic effect continues to be problematic. This study investigates the effect of betahistine on amikacin-induced ototoxicity.
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    Effect of nasal antihistamine on secretory IgA in nasal lavage of rats
    (2018-01-01) Dogan, REMZİ; AKSOY, Fadlullah; Goktas, Seda Sezen; Kocak, Ilker; Yildirim, YAVUZ SELİM; Incir, Said; Ozturan, ORHAN; DOĞAN, REMZI; AKSOY, FADLULLAH; YILDIRIM, YAVUZ SELİM; ÖZTURAN, ORHAN
    The humoral IgA is an immunoglobulin which plays a defensive role for organisms on mucosal surfaces. Today, intranasal antihistamines are effectively used in the treatment of allergic rhinitis. In our study, the effect of azelastine hydrochloride-a nasal antihistaminic-on humoral IgA of the nasal mucosa has been reviewed empirically. Twenty-four female Sprague-Dawley rats were included in our study. The rats were divided into three groups randomly. Group 1(azelastine hydrochloride): rats in this group had nasal azelastine hydrochloride (0.05%) applied for 30 days at 10 A mu l/nostril dosage. Group 2 (saline): saline (0.09%) was applied to the rats in this group for 30 days at 10 A mu l/nostril dosage. Group 3 (control): no application was made throughout the study. The chemicals applied in Groups 1 and 2 were applied to both nostrils by mounting a flexible micropipette to the end of an insulin injector. At the beginning of the study, nasal lavage was performed to both nostrils of the rats in every group on the 15th and 30th day to aspirate irrigation solution (distilled water). The aspirated liquids were kept at - 80A degrees temperature and reviewed together at the end of study. Within-group comparisons: in Group 1 (azelastine hydrochloride), the humoral IgA value on the 15th day was significantly higher than the basal value (p = 0.037). There is a significant difference between humoral IgA value on the 30th day and humoral IgA value on the 15th day (p = 0.045). In Group 2 (saline), no significant difference is available between basal, 15th day and 30th day humoral IgA values (p = 0.265). In Group 3 (control), no significant difference is available between basal, 15th day and 30th day humoral IgA values (p = 0.374). Between-group comparison: there is no significant difference in between-group humoral IgA basal values (p = 0.714). On days 15 and 30, Humoral IgA value of Group 1 was significantly higher than that of Groups 2 and 3 (p = 0.013, p = 0.024, respectively). According to the results we achieved in our study, nasal antihistaminic (azelastine hydrochloride) significantly increases the level of humoral IgA. Our study is the first one in the literature to reveal a relation between nasal antihistaminic and humoral IgA and there is a further need for clinical, randomized and prospective studies.
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    Subcutaneous Allergen-Specific Immunotherapy in Allergic Rhinitis
    (2011-06-01) AKSOY, Fadlullah; DEMIRHAN, Hasan; Ozturan, ORHAN; Yildirim, YAVUZ SELİM; AKSOY, FADLULLAH; ÖZTURAN, ORHAN; YILDIRIM, YAVUZ SELİM
    Objective: To evaluate the results of subcutaneous allergen-specific immunotherapy administered to patients with allergic rhinitis.Material and Methods: The medical records of 42 patients who received immunotherapy between January 2002 and December 2008 according to the criteria specified by the World Health Organization and completed the treatment, were retrospectively evaluated. Median symptom seventies, total symptom scores, skin sensitivities to allergic skin tests, need for medical treatment and levels of recovery according to the visual analogue scale were recorded before and after subcutaneous allergen-specific immunotherapy.Results: A total of 42 patients (15 men and 27 women), between 10-54 (median age 27.9 +/- 10.4 years) years of age were included in the study. Among the study group, 90.5% had perennial allergic rhinitis and 33.3% had a positive family history. Half of the patients were allergic to one substance and the other half was found to be allergic to more than one substance. Single allergen immunotherapy was used in the majority (85.7%) of the patients and few cases (14.3%) received parallel therapy. The decrease in the median symptom severity was found to be statistically significant (P<0.05). Before the administration of subcutaneous allergen-specific immunotherapy, total symptom scores were between 6-12 (median 9.50 +/- 1.48) and after treatment, total symptom scores decreased to levels between 0-6 (median 3,64 +/- 0.94). This decrease was statistically significant (P<0.05). The decrease in the median value of total symptom scores was 61.6%. In 62% of our patients, medical therapy was not required after the administration of allergen-specific immunotherapy. Skin reactions to the post treatment prick tests diminished and the difference was statistically significant (P<0.05). After subcutaneous allergen-specific immunotherapy, the median value in the visual analogue scale (VAS) decreased to 3.17, from the pretreatment value of 8.56 (P<0.05).Conclusion: Subcutaneous allergen-specific immunotherapy is a long and demanding treatment process both for the patients and the physicians. However it is proven as a safe and efficient treatment modality in allergic rhinitis if used properly and with a correct indication.VAS can be used in the evaluation of the response to therapy in patients with allergic rhinitis.
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    Effect of Postrhinoplasty Taping on Postoperative Edema and Nasal Draping A Randomized Clinical Trial
    (2016-05-01) TUGRUL, Selahattin; Yildirim, YAVUZ SELİM; VEYSELLER, Bayram; Eren, SABRİ BAKİ; AKSOY, Fadullah; Uysal, Omer; Ozturan, ORHAN; YILDIRIM, YAVUZ SELİM; TUĞRUL, SELAHATTİN; EREN, SABRİ BAKİ; AKSOY, FADLULLAH; UYSAL, ÖMER; ÖZTURAN, ORHAN
    BACKGROUND Edema persists for months after rhinoplasty. Numerous modalities have been described to counteract postoperative edema.