Person: ASİL, TALIP
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Publication Open Access Endovascular Therapy of Acute Ischemic Stroke by Interventional Cardiologists: National Initial Experience(2013-10-29) TASAL, Abdurrahman; Bacaksiz, AHMET; VATANKULU, Mehmet Akif; SONMEZ, Osman; TURFAN, Murat; ERDOGAN, Ercan; KARADELI, Hasan Huseyin; Kolukisa, MEHMET; KUL, Seref; ALTINTAS, Ozge; Asil, TALİP; GOKTEKIN, Omer; BACAKSIZ, AHMET; KOLUKISA, MEHMET; ASİL, TALIPObjectives: We report our initial experience with thrombectomy devices in patients with acute ischemic stroke. Study design: Demographic, clinical, and angiographic findings of 19 consecutive patients (7 females and 12 males; mean age 61.4±12.5 years) with acute ischemic stroke were evaluated retrospectively. Results: The mean initial National Institutes of Health Stroke Scale (NIHSS) score was 19.5±5.6. Middle cerebral artery was the occluded artery in all of the patients (proximal occlusion in 11, distal in 8 and tandem occlusions in 7 patients). Successful revascularization was achieved in 16 patients (84%). The mean NIHSS score was 8.4±8.2 at 24 hours after the procedure, and 60% of patients showed a modified Rankin scale score of ≤2 at 90 days. New occlusion by migrated emboli was observed in 2 (11%) cases. None of the patients had experienced post-procedural symptomatic intracerebral hemorrhage; 3 patients died during the three-month follow-up. In all patients, thrombectomy was performed with retrievable Solitaire AB stent system. Conclusion: This single-center experience with mechanical thrombectomy devices demonstrated that high success rates can be achieved by experienced interventional cardiologists in equipped cath labs throughout the country.Publication Open Access One-year follow-up in patients with brainstem infarction due to large-artery atherothrombosis(2015-01-01) Kolukisa, MEHMET; GUELTEKIN, Tugce Ozdemir; BARAN, Gozde Eryigit; Aralasmak, AYŞE; KOCAMAN, Guelsen; GUERSOY, Azize Esra; Asil, TALİP; KOLUKISA, MEHMET; ARALAŞMAK, AYŞE; GÜRSOY, AZIZE ESRA; ASİL, TALIPBackground: Posterior circulation infarction accounts for approximately 25% of the ischemic strokes. A number of different conditions may be associated with the development of brainstem infarction. Prognosis and recurrence rate of brainstem infarction due to large-artery atherothrombosis is still controversial. Methods: A total of 826 patients with ischemic stroke were admitted to our clinic during a 15-month period. Patients with clinical and radiological evidence of brainstem infarction were comprehensively assessed with appropriate vascular imaging modalities and for cardiological causes. Subjects with an established diagnosis of large-artery atherothrombosis were followed up for 1 year in terms of prognosis and recurrence rates. Results: Of the 101 patients with an established brainstem infarction, the diagnostic work-up indicated the presence of large-artery atherothrombosis as the causative factor in 53. A recurrent stroke was detected in the posterior circulation within the first 3 months in 5.8% and within 1 year in 9.8% of these individuals. The 1-year mortality rate was 11.7%. All patients with recurrent stroke had intracranial vascular narrowing at baseline. Conclusion: Our findings demonstrate a particularly high rate of recurrence and mortality at 1 year among patients who have a brainstem infarction due to intracranial arterial stenosis. Keywords: posterior circulation, intracranial arteries, extracranial arteries, stroke, vertebral artery, basilar arteryPublication Open Access The association of vertebrobasilar calcification with etiological subtypes, stroke recurrence and outcome in acute brainstem ischemic stroke.(2017-11-01) GÖKÇAL, E; NİFTALİYEV, ELVİN; GUELTEKIN, TUGCE OZDEMIR; KOLUKISA, MEHMET; ASİL, TALİP; KOLUKISA, MEHMET; ASİL, TALIPPublication Open Access Multiple Spontaneous Intracranial-Extracranial Arterial Dissections in a Patient with Osteogenesis Imperfecta(2017-01-01T00:00:00Z) KOLUKISA, MEHMET; GÖKÇAL, ELİF; GÜRSOY, Azize Esra; DENİZ, ÇİĞDEM; ARALAŞMAK, Ayşe; ASİL, Talip; KOLUKISA, MEHMET; GÖKÇAL, ELİF; GÜRSOY, AZIZE ESRA; DENİZ, ÇİĞDEM; ARALAŞMAK, AYŞE; ASİL, TALIPA 40-year-old male with osteogenesis imperfecta (OI) was admitted to the hospital with an acute right monoparesis. Diffusion-weighted MRI showed infarction in the territory of the left anterior cerebral artery (ACA) and in the left posterior cerebral artery (PCA). In his vascular imaging, occlusion of the left vertebral artery (VA) starting from V2 segment was consistent with dissection and pseudoaneurysm in the right ACA. We presented this case because of the presence of spontaneous and simultaneous occurrence of both intracranial and extracranial arterial dissections in OI.Publication Open Access Craniocervical Dissections: Radiologic Findings, Pitfalls, Mimicking Diseases: A Pictorial Review(2018-01-01) MEHDI, Elnur; Aralasmak, AYŞE; Toprak, HÜSEYİN; Yildiz, Seyma; Kurtcan, SERPİL; Kolukisa, MEHMET; Asil, TALİP; Alkan, ALPAY; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; YILDIZ, ŞEYMA; KURTCAN, SERPİL; KOLUKISA, MEHMET; ASİL, TALIP; ALKAN, ALPAYBackground: Craniocervical Dissections (CCD) are a crucial emergency state causing 20% of strokes in patients under the age of 45. Although DSA (digital substraction angiography) is regarded as the gold standard, noninvasive methods of CT, CTA and MRI, MRA are widely used for diagnosis. Aim: Our aim is to illustrate noninvasive imaging findings in CCD. Conclusion: Emphasizing on diagnostic pitfalls, limitations and mimicking diseases.Publication Open Access A CADASIL Case Presenting with Progressive Bulbar Palsy Caused by Acute Simultaneous Multiple Subcortical Infarcts(2019-04-01T00:00:00Z) GÖKÇAL, ELİF; KOLUKISA, MEHMET; Mustafayev, Nihat; ASİL, Talip; GÖKÇAL, ELİF; KOLUKISA, MEHMET; ASİL, TALIPCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an adult-onset inherited small vessel disease of the brain caused by NOTCH3 mutations. Clinical characteristics of CADASIL include recurrent infarctions, migraine with aura, mood disturbances and cognitive impairment. We report a 35 year-old migraine-free patient with unusual presentation with acute simultaneous multiple subcortical infarctions causing progressive bulbar palsy as the initial manifestation. Hepresented with slurred speech progressing to anarthria and bilateral palsy of lower motor cranial nerves within 24 hour. Initial acute subcortical infarcts enlarged and new infarcts developed in bilateral hemispheres. There was diffuse leukoencephalopathy involving temporal horns and the patient had positive familiy history of migraine and young stroke. CADASIL was diagnosed genetically when NOTCH3 mutationwas shown. The patient improved after treatment with liquid hydration and antiplatelet agent. We experienced with the patient that CADASIL may present with unusual progressive manifestations and bilateral simultaneous infarctions. Irrespective of clinical presentation, patients with leukoencephalopathy and positive familiy history should be tested for NOTCH3 mutation.