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ASİL, TALIP

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2010 - 201932020 - 20221
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    Evaluation of cerebral hemodynamic status in patients with unilateral symptomatic carotid artery stenosis during motor tasks, through use of transcranial Doppler sonography
    (2022-04-01T00:00:00Z) Milanlıoğlu, Aysel; YAMAN KULA, ASLI; KOLUKISA, MEHMET; ASİL, Talip; YAMAN KULA, ASLI; KOLUKISA, MEHMET; ASİL, TALIP
    Background: Carotid artery stenosis increases cerebral ischemic event risk through changing different cerebral hemodynamic parameters. Objective: To investigate how cerebral hemodynamics in the M1 segment of middle cerebral artery change in patients with carotid artery stenosis, after motor tasks using transcranial Doppler sonography (TCD). Methods: Thirty-two healthy subjects and 30 patients with unilateral symptomatic carotid artery stenosis were recruited. The patient population was divided into three groups according to the degree of stenosis (group 1: ≥50 to 69%, group 2: 70 to 89% and group 3: ≥90 to 99%). TCD was used to measure the pulsatility index (PI) and cerebral vasomotor reactivity (CVR). Results: In the patient group, significant differences for symptomatic side PI values (p=0.01) and mean CVR increases (p=0.05) were observed, compared with the healthy controls. However, the difference was not statistically significant for asymptomatic side PI values and mean CVR increases. The results from the intergroup comparison showed significantly higher percentages of symptomatic and asymptomatic side CVR increases in group 1, compared with groups 2 and 3 (p=0.001 and p=0.002, respectively). Conclusions: Our study showed that cerebral autoregulation and hemodynamic mechanisms are impaired in patients with carotid artery stenosis. Furthermore, the impairment of PI and CVR tends to get worse with increasing degrees of stenosis. In addition, this study demonstrated that assessment of these two hemodynamic parameters in clinical practice might be helpful for monitoring the progress of carotid artery stenosis.
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    Association of Clinical, Imaging, and Thrombus Characteristics With Recanalization of Visible Intracranial Occlusion in Patients With Acute Ischemic Stroke
    (2018-09-01T00:00:00Z) Menon, Bijoy K.; Al-Ajlan, Fahad S.; Najm, Mohamed; Puig, Josep; Castellanos, Mar; Dowlatshahi, Dar; Calleja, Ana; Sohn, Sung-Il; Ahn, Seong H.; Poppe, Alex; Mikulik, Robert; Asdaghi, Negar; Field, Thalia S.; Jin, Albert; Asil, Talip; Boulanger, Jean-Martin; Smith, Eric E.; Coutts, Shelagh B.; Barber, Phil A.; Bal, Simerpreet; Subramanian, Suresh; Mishra, Sachin; Trivedi, Anurag; Dey, Sadanand; Eesa, Muneer; Sajobi, Tolulope; Goyal, Mayank; Hill, Michael D.; Demchuk, Andrew M.; ASİL, TALIP
    IMPORTANCE Recanalization of intracranial thrombus is associated with improved clinical outcome in patients with acute ischemic stroke. The association of intravenous alteplase treatment and thrombus characteristics with recanalization over time is important for stroke triage and future trial design.
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    Endovascular therapy of acute ischaemic stroke by interventional cardiologists: single-centre experience from Turkey
    (2014-11-01) GOKTEKIN, Omer; TASAL, Abdurrahman; UYAREL, Huseyin; VATANKULU, Mehmet Akif; SONMEZ, Osman; AY, Nuray; KUL, Seref; YAMAC, Hatice; ALTINTAS, Ozge; KARADELI, Hasan; Kolukisa, MEHMET; Aralasmak, AYŞE; Asil, TALİP; KAHRAMAN AY, NURAY; KOLUKISA, MEHMET; ARALAŞMAK, AYŞE; ASİL, TALIP
    Aims: We report our single-centre experience with the Solitaire AB self-expanding retrievable stent system in patients with acute ischaemic stroke.
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    Motor Neuron Disease Presenting with Dropped Head
    (2010-06-01T00:00:00Z) Balci, Kemal; Celik, Yahya; Asil, TALİP; Utku, Ufuk; ASİL, TALIP
    Motor neuron diseases are a group of progressive neurological disorders that destroy motor neurons that control voluntary muscle activity such as swallowing, walking, speaking and breathing. The common form of motor neuron disease is amyotrophic lateral sclerosis. Neurological examination presents specific signs associated with upper and lower motor neuron degeneration. In the absence of any biological marker, the diagnosis of motor neuron disease is based on clinical features, combined with the results of electromyography. Some patients of motor neuron disease with atypical presentation have been reported in the literature. We presented here a case of motor neuron disease with atypical presentation who had progressive weakness of the neck muscles.