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EŞREFOĞLU, MUKADDES

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EŞREFOĞLU
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Type: Article × Subject: Golgi apparatus ×

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Now showing 1 - 2 of 2
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    PublicationOpen Access
    The Golgi Apparatus with the Historical Point of View
    (2021-07-01T00:00:00Z) EŞREFOĞLU, MUKADDES; EŞREFOĞLU, MUKADDES
    Scientists were introduced to the Golgi apparatus (GA) in 1898, when it was discovered by Camillo Golgi in 1898 as a -cytoplasmic reticular network-. Researchers heard Camillo Golgi-s name not only because of the GA, but also because of many definitions such as Golgi silver impregnation techniques, Golgi type I and II cells, Golgi cells of the cerebellum, and Golgi tendon organ. In fact, although the GA beared the name of this scientist, many scientists did numerous studies on the morphological and functional properties of this unique organelle before him, simultaneously with him or after him. Despite the simple technical possibilities of the old times, the scientists, whom we gratefully commemorated, obtained magnificent findings about the GA and presented them to the world of science. In this short article, which was a review, the following historical developments, starting from the discovery of the GA, were summarized.
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    PublicationOpen Access
    The Golgi Apparatus: Morphology and Function with Recent Facts
    (2019-10-01T00:00:00Z) EŞREFOĞLU, MUKADDES; EŞREFOĞLU, MUKADDES
    At the center of the secretory pathway, the Golgi complex ensures correct processing and sorting of cargos towards their final destination sites which are the cytoplasm, plasma membrane, and endosome-lysosome system. Recent technological developments have discovered new morphological and functional charcteristics of the Golgi apparatus. In this review, I emphasize that the Golgi apparatus is not a stable organelle instead a highly dynamic organelle changing its morphological and functional characteristics in different physiological and pathological conditions. It is not composed of a simple discontinuous parallel stacks but is composed of various domains such as cis-Golgi network, trans-Golgi network, and intercisternal network including various coated vesicles, vacuoles and tubules. Furthermore, the Golgi apparatus is not only involved in the secretory pathway, but also involved in the storage of Ca2+ very likely to smooth endoplasmic reticulum. Additionally, the Golgi apparatus might serve as a microtubule organizing center which is especially important to participate in Golgi reassembly after cell division.