Person: EŞREFOĞLU, MUKADDES
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Publication Metadata only Not only melatonin but also caffeic acid phenethyl ester protects kidneys against aging-related oxidative damage in Sprague Dawley rats.(2012-08-01) Eşrefoğlu, MUKADDES; IRAZ, M; ATES, B; GÜL, M; EŞREFOĞLU, MUKADDESPublication Metadata only The effects of caffeic acid phenethyl ester and melatonin on age-related vascular remodeling and cardiac damage.(2011-10-01) Eşrefoğlu, MUKADDES; GÜL, M; ATES, B; ERDOĞAN, A; EŞREFOĞLU, MUKADDESPublication Metadata only Protective effects of caffeic acid phenethyl ester and thymoquinone on toluene induced liver toxicity.(2019-05-01) Esrefoglu, MUKADDES; Bayındır, NİHAN; KURBETLI, N; Selek, S; Akbas, Tosunoglu; Meydan, SEDAT; OZTURK, OSMAN; Bulut, HURİ; Meral, I; MEYDAN, SEDAT; EŞREFOĞLU, MUKADDES; SELEK, ŞAHABETTİN; ÖZTÜRK, OSMAN; BAYINDIR, NİHAN; BULUT, HURI; MERAL, İSMAİLPublication Metadata only Comparison of the efficacy of multiple antioxidant and hyperbaric oxygen treatments in the prevention of ischemia and necrosis of local random McFarlane skin flap.(2021-02-26T00:00:00Z) Dogan, Remzi; Metin Guler, Eray; Kocyigit, ABDÜRRAHİM; Bayindir, Nihan; Mirasoglu, Bengisu Oroglu; Yenigun, Alper; DOĞAN, REMZI; KOÇYİĞİT, ABDÜRRAHİM; EŞREFOĞLU, MUKADDES; YENİGÜN, ALPER; ÖZTURAN, ORHANPublication Metadata only Melatonin and CAPE are able to prevent the liver from oxidative damage in rats: an ultrastructural and biochemical study.(2012-05-01) Esrefoglu, MUKADDES; IRAZ, M; ATES, B; GÜL, M; EŞREFOĞLU, MUKADDESPublication Metadata only Therapeutic effects of melatonin and quercetin on carbon tetrachloride-induced cardiac damage in rats(2016-03-01) ELBE, HÜLYA; EŞREFOĞLU, MUKADDES; CETIN, A; TAŞLIDERE, ELİF; ATES, BURHAN; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFPublication Metadata only Prenatal and postnatal development of the stomach in Wistar albino rats.(2014-05-01) CETIN, A; EŞREFOĞLU, MUKADDES; EŞREFOĞLU, MUKADDESPublication Metadata only Ascorbic acid and beta-carotene reduce stress-induced oxidative organ damage in rats.(2016-10-01) Esrefoglu, MUKADDES; AKINCI, A; TASLIDERE, ELİF; ELBE, H; CETIN, A; ATES, B; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFPublication Metadata only Treatment of Ulcerative Colitis Disease with Rosmarinus officinalis(2017-01-01T00:00:00Z) YILMAZ, ANIL; UÇKAYA, FATİH; Bayındır, Nihan; TOPRAK, ALİ; GÜLER, ERAY METİN; EŞREFOĞLU, MUKADDES; TOPÇU, GÜLAÇTI; UÇKAYA, FATİH; TOPRAK, ALİ; GÜLER, ERAY METİN; EŞREFOĞLU, MUKADDES; TOPÇU, GÜLAÇTIPublication Metadata only Assessment of the effectiveness of cyclosporine nasal spray in an animal model of allergic rhinitis(2018-01-01) Senturk, EROL; Yildirim, YAVUZ SELİM; Dogan, REMZİ; Ozturan, ORHAN; Guler, ERAY METİN; AYDIN, Mehmet Serif; Kocyigit, ABDÜRRAHİM; Esrefoglu, MUKADDES; Kocak, Ilker; ŞENTÜRK, EROL; YILDIRIM, YAVUZ SELİM; DOĞAN, REMZI; ÖZTURAN, ORHAN; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; EŞREFOĞLU, MUKADDESThe aim of this study is to show if cyclosporine has an antiallergic role in a rat model of ovalbumin-induced allergic rhinitis. The 54 rats were divided into six equal groups. The first group was a negative control group without induced allergic rhinitis; the second group a positive control with induced allergic rhinitis not receiving treatment. The remaining four groups, after induction of allergic rhinitis, received intranasal cyclosporine treatment in doses of 0.05, 0.1, or 0.2% or nasal steroid treatment. In the biochemical examination, on the surface of the tissue tumor necrosis factor (TNF) interferon (IFN), interleukin (IL)-5, IL-13, as well as IL-2, IL-4, IL-17A, and IgE were studied. Histologically, ciliary loss, increase of goblet cells, vascular congestion, and the degree of eosinophil infiltration were rated. In all treatment groups, on average, a significant reduction in all histological and biochemical values was found compared to the positive control group. Comparing each of the three cyclosporine-using groups with the group of nasal corticosteroid did not show any significant difference in the average scores. Cyclosporine nasal drops are effective to be used in an animal model of experimental allergic rhinitis without systemic effects.