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ÇAMLI, AHMET ADİL

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AHMET ADİL
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    The effect of fibromyalgia on bone mineral density in patients with hypothyroidism
    (2019-05-01T00:00:00Z) TAŞPINAR, ÖZGÜR; KESKİN, YAŞAR; kiziltan, huriye; ÇAMLI, AHMET ADİL; URKMEZ, BERNA; mutluer, ahmet serdar; AYDIN, TEOMAN; eriş, ali h; KESKİN, YAŞAR; AYDIN, TEOMAN; ÇAMLI, AHMET ADİL
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    PublicationOpen Access
    An Iron Deficiency Anemia Case That Came with Raw Rice Consumption
    (2015-02-01) ÇAMLI, AHMET ADİL; KARATOPRAK, CUMALİ; ÇETİN, GÜVEN; ZORLU, MEHMET; ALAY, MURAT; ÇAMLI, AHMET ADİL; KARATOPRAK, CUMALİ; ÇETİN, GÜVEN; ZORLU, MEHMET
    Pica is the chronic consumption of edible or nonedible materials that is thought to be caused by mental problems, pregnancy, or anemia. We wanted to report this case, which we have not seen in the literature before, of a pica patient who consumed raw rice due to iron deficiency anemia. A 26-year-old female patient was brought to the internal medicine polyclinic by her mother with complaints of consuming a bowl of raw rice (200 gr) every evening. The patient was treated with parenteral ferik hydroxide + sucrose complex (2700 mg) for 5 days. After 15 days, when she came to control her will to eat raw rice had been lost completely. As a result, the attention of doctors and family members for pica due to treatable causes, such as anemia, will prevent many probable complications.
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    Evaluation of the relationship between serum apelin levels and vitamin D and mean platelet volume in diabetic patients
    (2014-09-01) Buyukaydin, BANU; Zorlu, MEHMET; Cakirca, MUSTAFA; KESGIN, Sidika; YAVUZ, Erdinc; ARDIC, Cuneyt; Camli, AHMET ADİL; CIKRIKCIOGLU, Mehmet Ali; KISKAÇ, MUHARREM; ZORLU, MEHMET; ÇAKIRCA, MUSTAFA; KARATOPRAK, CUMALİ; BÜYÜKAYDIN, BANU; ÇAMLI, AHMET ADİL
    Objectives. - It was reported that Vitamin D deficiency was associated with a greater risk of cardiometabolic diseases, obesity, impaired glucose tolerance and diabetes mellitus type 2, arterial hypertension, and dyslipidemia. Apelin is an adipocytokine suspected to have a role in skeletal muscle glucose utilization and glycemic regulation which may be a promising treatment modality for diabetes. It was recently reported that increased mean platelet volume (MPV) was emerging as an independent risk factor for thromboembolism, stroke, and myocardial infarction. In patients with diabetes, MPV was higher compared with the normal glycemic controls; in addition, it has been proposed that an increase in MPV may play a role in the micro- and macro-vascular complications related to diabetes. We postulated that deficiency in Vitamin D levels might be associated with higher MPV and lower serum apelin levels leading a further increase in insulin resistance in diabetic patients. So, we aimed to investigate Vitamin D levels, MPV and serum apelin levels in diabetic patients and their correlations between each other. Materials and method. - This is a cross-sectional study design. Seventy-eight patients with Diabetes Mellitus type 2, admitted to our outpatient clinic of internal medicine department at Bezmialem Vakif University, were included in our study. Forty-one patients were female; 37 patients were male. Serum apelin levels, fasting glucose levels, urea, creatinine, triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), fasting serum insulin level, HbAl(c), free T3, free T4, TSH, vitamin D (25-OH Vitamin D) and complete blood counts were analyzed in all subjects. Results. - Each sex was analyzed separately. We found that a positive correlation existed between serum apelin levels and BMI in female patients. (r: 0.380, P: 0.014) There was also a significant positive correlation between MPV and HbAl, and fasting glucose levels and a negative correlation between MPV and PLT. (r: 0.377, P: 0.021; r: 0.395, P: 0.014; r: 0.401, P: 0.011; respectively) We failed to show a significant relationship between serum vitamin D levels, serum apelin levels and MPV in patients with diabetes mellitus type 2. Conclusion. - We failed to show an association between vitamin D, apelin and MPV higher volumes of which may have a role in cardiovascular complications related to diabetes by increasing platelet activation. (C) 2014 Published by Elsevier Masson SAS.
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    ASSESSMENT OF PARAOXONASE AND ARYLESTERASE ANTIOXIDATIVE PARAMETERS IN RHEUMATIC DISEASES
    (2016-01-01) Keskin, YAŞAR; Aydin, TEOMAN; TAŞPINAR, ÖZGÜR; KEPEKÇİ, MÜGE; Ozer, O. F.; Selek, S.; Camli, AHMET ADİL; Mutluer, A. S.; KESKİN, YAŞAR; AYDIN, TEOMAN; ÖZER, ÖMER FARUK; SELEK, ŞAHABETTİN; ÇAMLI, AHMET ADİL
    The aim of this study is to evaluate the patient stress markers which has the early stage rheumatoid arthritis (RA). Blood samples were collected from the patients diagnosed with rheumatoid arthritis according to American Rheumatism Association ACR 2010 criteria, but not employed the medication of DMARD (Disease-modifying antirheumatic drugs) in order to examine the stress parameters of total oxidant status, total antioxidant status, paraoxonase, paraoxonase NaCl, arylesterase concentration. Twenty nine patients diagnosed with early stage RA and 61 healthy control group included in the study. Peripheral blood samples were examined for all the assays. The average age of the patients was 39.91 +/- 13.32 and their average BMI was 28.56 +/- 4.15. ESR and CRP values have been found significantly high levels in RA group when we compare with control group. OSI values, which means oxidant parameters, have been found significantly high compared to the control group. When the parameters of arylesterase were compared to the control group, the values of control group were significantly high.
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    RELATIONSHIP BETWEEN RHEUMATOID ARTHRITIS DISEASE ACTIVITY AND MYELOPEROXIDASE AND CATALASE ACTIVITIES AND THIOL LEVELS
    (2016-01-01) Camli, AHMET ADİL; TAŞPINAR, ÖZGÜR; Aydin, TEOMAN; KEPEKÇİ, MÜGE; Ozer, O. F.; Keskin, YAŞAR; Selek, S.; Mutluer, A. S.; ÇAMLI, AHMET ADİL; AYDIN, TEOMAN; ÖZER, ÖMER FARUK; SELEK, ŞAHABETTİN
    The aim of this study is to evaluate myeloperoxidase activity, catalase activity and thiol levels at early with rheumatoid arthritis patients. Blood taken from the patients was diagnosed with RA according to American Rheumatism Association ACR 2010 criteria, but not employed the medication of DMARD (Disease-modifying antirheumatic drugs) in order to examine the antioxidant parameters of myeloperoxidase activity, catalase activity and thiol levels. Twenty nine patients with early RA and 61 healthy controls were included in the study. Peripheral blood samples were used for all the assays. The average age of the patients was 39.91 +/- 13.32 and their average BMI was 28.56 +/- 4.15. Erytrocyte sedimentation rate (ESR) and C-reactive protein (CRP) values have been found significantly high levels in RA group when we compare with control group. Catalase activity and thiol levels which means antioxidant parameters, have been found significantly low levels according to control group. When the parameters of myeloperoxidase activity were compared to the control group, the values of control group were significantly high. Stronger response in patients with early RA suggests that antioxidant markers may be useful in evaluating the progression of RA as well as in elucidating the mechanisms of disease pathogenesis.
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    Psychological effects of calisthenic exercises on neuroinflammatory and rheumatic diseases
    (2015-10-01) TAŞPINAR, ÖZGÜR; Aydin, TEOMAN; CELEBI, A.; Keskin, YAŞAR; YAVUZ, SELÇUK; GÜNEŞER, MERYEM; Camli, AHMET ADİL; TOSUN, MEHMET; CANBAZ, N.; GÖK, MURAT; AYDIN, TEOMAN; KESKİN, YAŞAR; ÇAMLI, AHMET ADİL
    The aim of this study was to evaluate the effects of calisthenic exercises on psychological status in patients with ankylosing spondylitis (AS) and multiple sclerosis (MS).
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    SARCOPENIA EVALUATION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
    (2016-03-01) HOCAOGLU, ILKNUR TURK; AYDIN, TEOMAN; ÇAMLI, AHMET ADİL; TAŞPıNAR, ÖZGÜR; ÖZDER, ACLAN; KIZILTAN, HURİYE ŞENAY; DENIZLI, EBRU; ÖZER POŞUL, SEVDE; KESKİN, YAŞAR; KEPEKÇİ, MÜGE; ERİŞ, ALİ HİKMET; AYDIN, TEOMAN; ÇAMLI, AHMET ADİL; ÖZDER, ACLAN; KIZILTAN, HURİYE ŞENAY; ERİŞ, ALİ HİKMET; KESKİN, YAŞAR
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    Evaluation of the effectiveness of home based or hospital based calisthenic exercises in patients with ankylosing spondylitis.
    (2016-11-21) Aydın, TEOMAN; TAŞPıNAR, ÖZGÜR; SARIYILDIZ, MUSTAFA AKİF; GÜNEŞER, MERYEM; Keskin, YAŞAR; CANBAZ, N; GÖK, MURAT; Camli, AHMET ADİL; Kiziltan, HURİYE ŞENAY; Eris, ALİ HİKMET; AYDIN, TEOMAN; ÇAMLI, AHMET ADİL; KIZILTAN, HURİYE ŞENAY; ERİŞ, ALİ HİKMET
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    PublicationOpen Access
    Vaspin and lipocalin-2 levels in severe obsructive sleep apnea.
    (2014-06-01) KıSKAÇ, MUHARREM; ZORLU, MEHMET; AKKOYUNLU, MUHAMMED EMİN; KILIC, ERDEM; CAKIRCA, MUSTAFA; Karatoprak, CUMALİ; YAVUZ, E; ARDIC, C; CAMLI, AHMET ADİL; CIKRIKCIOGLU, M; KART, L; KISKAÇ, MUHARREM; ZORLU, MEHMET; AKKOYUNLU, MUHAMMED EMİN; KILIÇ, ERDEM; KARATOPRAK, CUMALİ; ÇAKIRCA, MUSTAFA; ÇAMLI, AHMET ADİL
    Background: Vaspin and lipocalin-2 are less-known recent members of adipocytokine family. There are ongoing studies investigating the role of vaspin ve lipocalin-2 in metabolic syndrome (MS). Obstructive sleep apnea syndrome (OSAS) is independently associated with an increased prevalence of MS. We aimed to measure the levels of vaspin and lipocalin-2 which are secreted from adipocytes in patients with severe OSAS and examine the relationship between these two adipocytokines and OSAS. Methods: The study consisted of two groups: severe OSAS patients with an apnea-hypopnea index (AHI) of >30/h (OSAS group, 34 subjects) and age-matched healthy volunteers with a AHI <5/h (control group, 25 subjects) Serum levels of vaspin and lipocalin-2 in these two groups were compared. Results: Serum levels of vaspin were significantly lower in OSAS group; patients with severe OSAS compared with control group; healthy volunteers (OSAS group: 0.69±0.5 vs. control group: 1.24±1.13; P=0.034). The difference between the two groups in terms of serum levels of lipocalin-2 has not reached statistical significance (OSAS group: 61.6±18.2 vs. control group: 68.5±20.1; P=0.17). Conclusions: We found that serum vaspin levels were significantly lower in patients with severe OSAS compared with healthy controls. Lipocalin-2 levels were similar. The decrease in serum vaspin levels in severe OSAS patients may be important in diagnosis and follow-up of these patients.
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    PublicationOpen Access
    Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients
    (2014-01-01) Cakirca, MUSTAFA; Soysal, Pinar; Zorlu, MEHMET; Kiskac, MUHARREM; Kanat, Mustafa; CIKRIKCIOGLU, Mehmet Ali; Karatoprak, CUMALİ; HURSITOGLU, Mehmet; Camli, AHMET ADİL; ERKOC, Reha; ABDUL-GHANI, Muhammad; ÇAKIRCA, MUSTAFA; KARATOPRAK, CUMALİ; ZORLU, MEHMET; KISKAÇ, MUHARREM; SOYSAL, PINAR; ÇAMLI, AHMET ADİL
    Aims: A close association has been demonstrated between increased cardiovascular risk and high asymmetric dimethylarginine (ADMA) levels in type 2 diabetes mellitus (DM) patients. We planned to measure serum ADMA levels in type 2 DM patients using vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. Materials and methods: A total of 68 type 2 DM patients who were on metformin were enrolled in the study. Based on the glycemic levels of patients, vildagliptin was added on to treatment in 33 patients. Patients were followed for 6 months. Serum ADMA, C-reactive protein, and fibrinogen levels were compared in groups of patients using metformin or metformin + vildagliptin, after 6 months. Results: Serum ADMA levels were found to be significantly lower in the group using vildagliptin compared to the group using metformin + vildagliptin (P<0.001). However, serum C-reactive protein and fibrinogen levels were statistically similar in the two study groups (P=0.34 and P=0.23, respectively). Conclusion: Metformin + vildagliptin treatment was observed to lower serum ADMA levels in type 2 DM patients. Our findings notwithstanding, large-scale prospective randomized controlled studies are warranted to conclude that vildagliptin provides cardiovascular protection along with diabetes regulation. Keywords: asymmetric dimethylarginine (ADMA); dipeptidyl peptidase-4 (DPP-4) inhibitor; type 2 diabetes mellitus; vildagliptin.