Person: BULUT, HURI
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Publication Metadata only Effects of Keto-Analogs in the Pathologic Findings of Diabetic Nephropathic Rats(2020-01-01T00:00:00Z) Bildaci, Yelda Deligoz; ÇOBAN, Ganime; Bulut, Huri; GÜRSU, Meltem; ELÇİOĞLU, Ömer Celal; KAZANCIOĞLU, Rümeyza; BULUT, HURI; GÜRSU, MELTEM; ELÇİOĞLU, ÖMER CELAL; KAZANCIOĞLU, RÜMEYZAObjective: Some studies have shown that keto amino acids (KA) reduce proteinuria and improve renal function as well as nutritional status in patients with diabetic nephropathy. We aimed to compare the pathologic findings of kidneys of rats that were given protein-restricted diets enriched with KA with those of rats given protein-restricted diet alone.Publication Metadata only Effects of melatonin on both testicular regeneration and recovery of spermatogenesis in busulfan-treated rats(2022-01-01) Taşlıdere E.; Eşrefoğlu M.; Tok O.; Taşlıdere B.; Bulut H.; EŞREFOĞLU, MUKADDES; TAŞLIDERE, BAHADIR; BULUT, HURITesticular damage is one of the most hazardous effects of chemotherapy as it is frequently associated with oligozoospermia and azoospermia. This study aimed at evaluating the protective effect of melatonin in a rat model of busulfan-induced testicular injury. Rats were divided into four groups: control, melatonin, busulfan, busulfan plus melatonin. After 15 days, the semen was collected from the epididymis and testes were assessed. Sperm removed from cauda epididymis and analyzed for sperm count and viability. Testis tissues were also removed, fixed in formalin and were embedded in paraffin. Sections of testis tissue were stained with hematoxylin-eosin for histological examination and prepared for TUNEL (Terminal deoxynucleotide transferase dUTP Nick End Labeling) assay to detect apoptosis and PCNA (proliferating cell nuclear antigenassay) to detect proliferation cells. Serum and testes supernatants were separated to detect testosteron level and oxidative stress parameters. In histological examination, degenerative changes in seminiferous tubules were observed in the experimental groups. In biochemical examination, the total oxidant status (TOS) levels in Busulfan group were significantly higher than in the control group while the total antioxidant status (TAS) levels of all the groups were similar. In conclusion, the beneficial properties of melatonin treatment by its potent anti-oxidants may reduce adverse effects of chemotherapy in the reproductive system in a rodent system.Publication Metadata only The Acorn Honey Used for a Published Study was Mistakenly Listed as Quercus pyrenaica and Should Be Corrected to Quercus species(2022-07-01T00:00:00Z) KOÇYİĞİT, ABDÜRRAHİM; Aydogdu, Gokhan; BALKAN, EZGİ; YENİGÜN, Vildan Betül; GÜLER, ERAY METİN; BULUT, Huri; KÖKTAŞOĞLU, FATMANUR; GÖREN, AHMET CEYHAN; Atayoglu, Ali Timucin; KOÇYİĞİT, ABDÜRRAHİM; BALKAN, EZGİ; YENİGÜN, VILDAN BETÜL; GÜLER, ERAY METİN; BULUT, HURI; KÖKTAŞOĞLU, FATMANUR; GÖREN, AHMET CEYHAN