Person: TUĞRUL, SELAHATTİN
20 results
Search Results
Now showing 1 - 10 of 20
Publication Metadata only Adjunctive Use of the Dermocartilaginous Ligament for Dorsal Irregularities in Primary Rhinoplasty.(2018-09-01) YENIGUN, A; AKSOY, FEYZA MÜBERRA; Ozturan, ORHAN; TUGRUL, SELHATTİN; ÖZTURAN, ORHAN; YENİGÜN, ALPER; TUĞRUL, SELAHATTİN; AKSOY, FADLULLAHPublication Metadata only Effect of Submucosal Mesna Application on Mucoperichondrial Elevation in Septoplasty(2017-01-01) Dogan, REMZİ; Yenigun, ALPER; Eren, SABRİ BAKİ; Ozturan, ORHAN; Goktas, Seda Sezen; Tugrul, Selahattin; Calim, Omer Faruk; EREN, SABRİ BAKİ; YENİGÜN, ALPER; TUĞRUL, SELAHATTİN; DOĞAN, REMZI; ÇALIM, ÖMER FARUK; ÖZTURAN, ORHANObjective: It was revealed that the thiol compound named mesna chemically softens the connective tissue with submucosal injection, and facilitates the endoscopic submucosal dissection. The authors aimed to investigate the effect of mesna injection on mucoperichondrial elevation during septoplasty operation. Methods: This study was planned as a patient-control study and performed. Fifty-six patients who had septoplasty operation were divided into 2 groups that are submucosal mesna (group 1) and submucosal saline (group 2) applied ones. In both groups, the measurement was initiated by a timer during the start of septal incision and elevation processes. After bilateral subperichondrial and subperiostal elevation were finished, timer was stopped and time was recorded. After that, mucosal integrity was reviewed and mucosal damage status was recorded. The difficulty of mucoperichondrial elevation for the surgeon was recorded for each patient. Results: Twenty-five (44.7%) of the patients who participated in our study were females while 31 (55.3%) were males. The average elevation periods were 201.4 +/- 74.3 seconds in group 1 and 260.2 +/- 84.1 seconds in group 2. In mesna applied patients, elevation period was statistically and significantly shorter (P = 0.009). Impairment in mucosal integrity was observed as 33.3% in group 1 and 58.8% in group 2. In mesna applied patients, significantly less impairment in mucosal integrity was observed (P = 0.031). The average mucoperichondrial elevation difficulty for the surgeon is observed as 4.83 +/- 2.47 in group 1 and 6.5 +/- 1.9 in group 2. Mesna applied patients were defined as significantly easier patients for the surgeon (P = 0.006). Conclusion: Submucosal mesna application is an approach that provides a convenient, fast, and effective mucoperichondrial elevation in septoplasty and protects the mucosal integrity.Publication Metadata only Does systemic steroid deficiency affect inner ear functions?(2015-07-01) Dogan, REMZİ; MERIC, Aysenur; Gedik, Ozge; TUGRUL, Selahattin; Eren, SABRİ BAKİ; Ozturan, ORHAN; DOĞAN, REMZI; MERİÇ HAFIZ, AYŞENUR; GEDİK, ÖZGE; TUĞRUL, SELAHATTİN; EREN, SABRİ BAKİ; ÖZTURAN, ORHANPurpose: Today corticosteroids are employed for the treatment of various inner ear disorders. In this study we have investigated probable changes in hearing functions resulting from a deficiency of systemic steroid secretions.Publication Metadata only Evaluation of nasal mucociliary transport rate according to nasal septum deviation type(2016-07-01) Dogan, REMZİ; TUGRUL, Selahattin; Erdogan, EZGİ BAŞAK; Eren, SABRİ BAKİ; Ozturan, ORHAN; DOĞAN, REMZI; TUĞRUL, SELAHATTİN; ERDOĞAN, EZGİ BAŞAK; EREN, SABRİ BAKİ; ÖZTURAN, ORHANBackgroundNasal septum deviation (NSD) may affect mucociliary activity (MCA) to varying degrees, depending upon the severity of the deviation. We used rhinoscintigraphy to determine the impact of the various NSD types on MCA.Publication Metadata only Efficacy of nasal corticosteroid in preventing regrowth after adenoidectomy(2016-12-01) TUGRUL, Selahattin; Yildirim, YAVUZ SELİM; SENTURK, EROL; Eren, SABRİ BAKİ; Dogan, REMZİ; Ozturan, ORHAN; YILDIRIM, YAVUZ SELİM; ŞENTÜRK, EROL; EREN, SABRİ BAKİ; DOĞAN, REMZI; TUĞRUL, SELAHATTİN; ÖZTURAN, ORHANObjective: One of the most frequent reasons of nasal obstruction and sleep apnea in pediatrics is adenoid hypertrophy. Remaining adenoid tissue can reoccur following hypertrophied adenoid removal and a second operation may be needed. Nasal corticosteroids are utilized in order to reduce adenoid hypertrophy and eliminate adenoidectomy operation. The purpose of our study is to assess the effect of nasal corticosteroid administration after adenoidectomy on adenoid regrowth and symptom scores.Publication Open Access Effect of Radiofrequency on DNA Damage and Oxidative Status in Patients with Turbinate Hypertrophy.(2019-11-01) Tugrul, S; Koçyiğit, A; Senturk, E; Doğan, Remzi; Eren, SB; Ozturan, ORHAN; Kesgin, S; ŞENTÜRK, EROL; TUĞRUL, SELAHATTİN; DOĞAN, REMZI; EREN, SABRİ BAKİ; ÖZTURAN, ORHAN; KOÇYİĞİT, ABDÜRRAHİMThe radiofrequency devices that are used generate radiofrequency in the frequency range of 1.5 and 2.5 MHz. This study aims to demonstrate whether systematic oxidative status and DNA are influenced in this frequency range. In study, 27 patients who received radiofrequency treatment on inferior turbinate as they were diagnosed with inferior turbinate hypertrophy. DNA damage was assessed by alkaline comet assay in peripheral lymphocyte cells. Plasma levels of total antioxidant status (TAS), total oxidative status (TOS) were determined by using an automated measurement method and oxidative stress index (OSI) was calculated (OSI was calculated as: OSI = (TOS/TAS) × 100). There were increased in the OSI and TOS values on days 1 and 15 as compared to the samples taken before the radiofrequency administration. Significant decreases were seen in TAS values on days 1 and 15. As for the DNA damage, no significant differences were found on day 15 compared to the preoperative values even though there was a statistically insignificant increase on day 1. Administration of radiofrequency radiation on inferior turbinates results in increased oxidative stress in the acute period and a decrease in the anti-oxidative system. Although this effect causes a slight increase in the DNA damage in the early post-operative period, the damage is restored to the pre-operative levels on day 15. Therefore, we believe that a more conservative approach should be selected for radiofrequency treatment instead of using it routinely.Publication Metadata only Can Oxidative Stress Parameters Be Used as Biomarkers for the Discrimination of Malignant Head and Neck Tumors(2016-05-01) Dogan, REMZİ; HAFIZ, Aysenur Meric; TUGRUL, Selahattin; Ozturan, ORHAN; KESKIN, Siddika; Kocyigit, ABDÜRRAHİM; DOĞAN, REMZI; TUĞRUL, SELAHATTİN; ÖZTURAN, ORHAN; KOÇYİĞİT, ABDÜRRAHİMObjective: In this study the authors have investigated oxidative stress parameters in sera and tissues, and evaluated their significance for the differentiation of malignant and benign tumors.Publication Metadata only Evaluation of the protective effect of Botulinum toxin type A injection on otitis media with effusion(2017-01-01) Calim, Omer Faruk; Yildirim, YAVUZ SELİM; Dogan, REMZİ; Tugrul, SELHATTİN; Gedik, Ozge; Ozturan, ORHAN; ÇALIM, ÖMER FARUK; YILDIRIM, YAVUZ SELİM; DOĞAN, REMZI; TUĞRUL, SELAHATTİN; GEDİK, ÖZGE; ÖZTURAN, ORHANObjective: This study makes an analysis of the effect of Botulinum toxin type A on otitis media with effusion in rats.Publication Metadata only Dose and time dependent ototoxicity of aspartame in rats(2017-01-01) TUGRUL, Selahattin; Ozturan, ORHAN; Dogan, REMZİ; Gedik, Ozge; SJOSTRAND, Alev Pektas; Yildirim, YAVUZ SELİM; ÖZTURAN, ORHAN; DOĞAN, REMZI; TUĞRUL, SELAHATTİN; GEDİK, ÖZGE; YILDIRIM, YAVUZ SELİMConclusion: Low-dose administration of Aspartame (Ap) did not produce a significant ototoxic effect at the end of the 6th month. However, duration of the ototoxic effect is shortened and severity of the effect is increased as dose and duration of Ap administration is increased.Publication Metadata only Effect of Postrhinoplasty Taping on Postoperative Edema and Nasal Draping A Randomized Clinical Trial(2016-05-01) TUGRUL, Selahattin; Yildirim, YAVUZ SELİM; VEYSELLER, Bayram; Eren, SABRİ BAKİ; AKSOY, Fadullah; Uysal, Omer; Ozturan, ORHAN; YILDIRIM, YAVUZ SELİM; TUĞRUL, SELAHATTİN; EREN, SABRİ BAKİ; AKSOY, FADLULLAH; UYSAL, ÖMER; ÖZTURAN, ORHANBACKGROUND Edema persists for months after rhinoplasty. Numerous modalities have been described to counteract postoperative edema.